synof kid tablet - Chlorpheniramine Maleate (1mg) + Paracetamol (250mg) medicine

Dalcold C Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Seron Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of cold and allergy symptoms.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Dark urine or pale stools
  • Severe abdominal pain
  • Difficulty breathing or swelling of face, lips, or throat
  • Unusual bruising or bleeding
  • Seizures or confusion
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is synof kid tablet used for?

This medicine is a combination of Chlorpheniramine Maleate (an antihistamine) and Paracetamol (a pain reliever and fever reducer) used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever. It is available as a syrup for oral use.

  • Generic Name: Chlorpheniramine Maleate (1mg) + Paracetamol (250mg)
  • Manufacturer: Seron Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 synof kid tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में पानी आना, गले में खुजली और हल्के बुखार को कम करने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामिन मेलिएट और पैरासिटामोल होते हैं। यह 6 साल से बड़े बच्चों और वयस्कों के लिए है, लेकिन डॉक्टर की सलाह के बिना न दें।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुंह सूखना, धुंधली दृष्टि और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इसमें गंभीर एलर्जी, लीवर की क्षति और रक्त विकार हो सकते हैं। यदि आपको पीलिया, गहरे रंग का पेशाब, गंभीर पेट दर्द या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अधिक मात्रा में न लें क्योंकि इससे लीवर को नुकसान हो सकता है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं। शराब न पिएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। 5 दिन से अधिक बिना डॉक्टर की सलाह के न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 synof kid tablet Uses & Benefits

[{"condition":"Common cold","description":"Relieves runny nose, sneezing, watery eyes, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, nasal itching, and runny nose due to seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps relieve itching and hives of allergic origin.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for short-term sleep aid due to drowsiness caused by Chlorpheniramine.","evidence":"Limited"},{"condition":"Motion sickness","description":"May be used off-label to prevent nausea and vomiting associated with motion sickness.","evidence":"Limited"}]

Primary treatment for: Common cold and allergic rhinitis

Also treats: Urticaria, Allergic conjunctivitis

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (1mg) + Paracetamol (250mg)
Brand Namesynof kid tablet
ManufacturerSeron Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not refrigerate. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always measure the dose using a proper measuring cup or spoon, not a household spoon.
2
Take this medicine with food or milk if it upsets your stomach.
3
Avoid driving or operating heavy machinery until you know how this medicine affects you.
4
Do not take this medicine with other products containing Paracetamol to avoid overdose.
5
Consult your doctor if symptoms do not improve within 5 days or if they worsen.
6
Keep this medicine out of reach of children and store it properly.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Runny nose
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing
This medicine helps relieve sneezing due to allergies.
Likely Use
✅
Mild fever
Paracetamol in this medicine reduces fever.
Likely Use
❌
Severe headache
This medicine is not a primary treatment for severe headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine is well absorbed from the gastrointestinal tract after oral administration. Paracetamol is rapidly and completely absorbed from the gastrointestinal tract. Food may delay the absorption of Paracetamol slightly but does not significantly reduce the extent of absorption.
DistributionChlorpheniramine is widely distributed throughout the body and crosses the blood-brain barrier. Paracetamol is distributed widely into most body tissues, with a volume of distribution of about 0.9 L/kg.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismChlorpheniramine is metabolized in the liver primarily by CYP2D6 and CYP3A4 enzymes. Paracetamol is metabolized in the liver, mainly by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of Chlorpheniramine is approximately 12-15 hours in adults. The elimination half-life of Paracetamol is about 2-3 hours in adults with normal liver function.
ExcretionChlorpheniramine and its metabolites are excreted primarily in the urine. Paracetamol metabolites are excreted in the urine, with about 90% of the dose excreted within 24 hours.
BioavailabilityChlorpheniramine has a bioavailability of about 25-50% due to first-pass metabolism. Paracetamol has a high oral bioavailability of about 80-100%.
Onset of ActionChlorpheniramine begins to relieve allergic symptoms within 30-60 minutes after oral administration. Paracetamol starts reducing fever and pain within 30-60 minutes.
Peak Plasma TimeChlorpheniramine reaches peak plasma concentration in about 2-3 hours. Paracetamol reaches peak plasma concentration in about 0.5-2 hours.
Duration of ActionChlorpheniramine provides symptom relief for about 4-6 hours. Paracetamol provides pain and fever relief for about 4-6 hours.

How It Works

This medicine combines an antihistamine and an analgesic-antipyretic. Chlorpheniramine Maleate competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract, reducing allergic symptoms. Paracetamol acts primarily in the central nervous system to reduce fever and pain, possibly by inhibiting prostaglandin synthesis in the hypothalamus and blocking pain impulse generation.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on cells, preventing histamine from triggering allergic responses such as sneezing, itching, and runny nose.
2
Central nervous system depression: Chlorpheniramine crosses the blood-brain barrier and causes drowsiness by blocking histamine in the brain.
3
Anticholinergic action: Chlorpheniramine also blocks acetylcholine receptors, leading to dry mouth, blurred vision, and urinary retention.
4
Central analgesia and antipyresis: Paracetamol acts on the hypothalamus to lower fever and on the central nervous system to reduce pain perception.

💡 How to Take synof kid tablet

Strength: Each 5 mL contains Chlorpheniramine Maleate 1 mg and Paracetamol 250 mg.

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the exact dose.
3Take orally, with or without food.
4Follow the prescribed dose and frequency.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 10 mL (2 teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of Chlorpheniramine, such as drowsiness, confusion, and urinary retention. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Avoid in severe liver disease. Consult a doctor.
Maximum Daily DoseFor adults: Maximum 60 mL (12 teaspoons) in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of synof kid tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If drowsiness is excessive, consult your doctor.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. This usually resolves with continued use.
Blurred vision (Uncommon (1-5%))
Usually temporary. If persistent, consult your doctor.
Nausea (Uncommon (1-5%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience rash, swelling of face, lips, or throat, or difficulty breathing.
Liver damage (Paracetamol toxicity) (Rare (<0.1%) with normal doses)
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Blood disorders (e.g., thrombocytopenia, agranulocytosis) (Very rare (<0.01%))
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.

⚠️ Rare Side Effects

Photosensitivity
Avoid excessive sun exposure and use sunscreen.
Urinary retention
Consult your doctor if you have difficulty urinating.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Warfarin Major
Alcohol Major
Benzodiazepines Moderate
Tricyclic antidepressants Moderate
Donepezil Moderate
Antacids Minor
Activated charcoal Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Alcohol
  • Warfarin

⚡ Moderate Interactions

  • CNS depressants (e.g., benzodiazepines, opioids, sedatives)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Cholinesterase inhibitors (e.g., donepezil)

🍷 Alcohol Interaction

Alcohol should be strictly avoided while taking this medicine. It enhances the sedative effects of Chlorpheniramine and increases the risk of Paracetamol-induced liver damage.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Chlorpheniramine, Paracetamol, or any component of the formulation","Neonates and premature infants","Severe liver disease or severe active liver disease","Narrow-angle glaucoma","Urinary retention","Concurrent use with MAOIs"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Do not exceed recommended dose due to risk of liver damage.","Avoid alcohol.","Use with caution in patients with asthma, COPD, or sleep apnea.","Use with caution in elderly patients due to increased risk of confusion and falls.","Consult doctor before use in pregnancy or breastfeeding.","Do not use for more than 5 days without medical advice."]

🤱 Lactation Safety

Chlorpheniramine and Paracetamol are excreted in breast milk in small amounts. Consult your doctor before use while breastfeeding. Chlorpheniramine may cause drowsiness in the infant.

💊 Overdose Management

Overdose can cause severe liver damage from Paracetamol and anticholinergic toxicity from Chlorpheniramine. Symptoms include nausea, vomiting, abdominal pain, confusion, seizures, and coma. Seek emergency medical help immediately. Treatment may include activated charcoal, N-acetylcysteine for Paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose because the Paracetamol component can harm the liver in high amounts. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not drink alcohol while taking this medicine, as it increases the risk of liver damage and enhances drowsiness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for more than 5 days without consulting a doctor. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as drowsiness, confusion, dry mouth, and urinary retention. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to help your body recover from cold or allergies.
🥗
Stay hydrated by drinking plenty of fluids.
😴
Avoid exposure to allergens such as dust, pollen, and pet dander.
💧
Use a humidifier to ease nasal congestion.
🧘
Wash your hands frequently to prevent spreading infections.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Include warm soups and broths to soothe your throat.
Eat fruits rich in vitamin C to support your immune system.
Avoid cold drinks and ice cream if you have a sore throat.
Stay hydrated with water and herbal teas.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your work requires alertness.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 5 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Chlorpheniramine may lead to tolerance and dependence. Prolonged high doses of Paracetamol can cause liver damage. Regular monitoring of liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal rinse

Helps clear nasal congestion and allergens.

Evidence: Well-established
Steam inhalation

Can temporarily relieve nasal congestion.

Evidence: Limited
Antihistamine nasal sprays

Targeted relief for allergic rhinitis with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of the prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 30-year-old woman with seasonal allergies
She was prescribed this medicine for her runny nose and sneezing. She took it as directed and found relief within an hour. She experienced mild drowsiness, so she avoided driving. She was advised not to exceed the dose and to avoid alcohol.
💡 Lesson: This medicine effectively relieves allergy symptoms but can cause drowsiness; avoid driving and alcohol.
👤 A 45-year-old man with common cold and fever
He took this medicine for his cold symptoms and mild fever. His fever subsided and his runny nose improved. He was careful not to take additional Paracetamol products. He consulted his doctor after 4 days as symptoms persisted.
💡 Lesson: This medicine provides symptomatic relief but should not be used for more than 5 days without medical advice.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking a dose.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: Is it safe for children?

A: It is not recommended for children under 6 years without medical advice. Consult a pediatrician for appropriate dosing.

Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember, but if it is almost time for your next dose, skip it and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for synof kid tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take extra doses for faster relief.
    Fact: Taking more than the recommended dose can cause serious liver damage due to Paracetamol.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine Maleate + Paracetamol syrup (generic)

Brand Alternatives

  • Dalcold C Syrup

📊 Comparison with Similar Medicines

[{"medicine":"Dalcold C Syrup","composition":"Chlorpheniramine 1mg + Paracetamol 250mg per 5mL","onset":"30-60 minutes","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine + Paracetamol syrup","composition":"Cetirizine 5mg + Paracetamol 250mg per 5mL","onset":"30-60 minutes","sedation":"Low","duration":"12-24 hours"}]

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