coldutch tablet - Paracetamol (NA) + Phenylpropanolamine (NA) medicine

coldutch tablet

4.5 (19 reviews)
๐Ÿญ Dutch Remedies ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is coldutch tablet used for?

Anglocet Plus Tablet (Paracetamol + Phenylpropanolamine) is used to treat RESPIRATORY. It contains Paracetamol (NA) + Phenylpropanolamine (NA), which Paracetamol: Inhibits COX enzymes centrally, reducing prostaglandin synthesis. P. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Paracetamol + Phenylpropanolamine
  • Manufacturer: Dutch Remedies
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š coldutch tablet Uses & Benefits

Fever, headache, cold symptoms, nasal congestion.

Off-label uses: None established.

๐Ÿ“‹ Drug Information

Generic Name(s)Paracetamol + Phenylpropanolamine
Brand NameAnglocet Plus Tablet
ManufacturerDutch Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAnalgesic, Antipyretic, Decongestant
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionParacetamol: Rapidly and completely absorbed from GI tract. Phenylpropanolamine: Well absorbed orally.
DistributionParacetamol: Widely distributed; crosses placenta. Phenylpropanolamine: Distributed throughout body; crosses blood-brain barrier.
Protein BindingParacetamol: 10-25%. Phenylpropanolamine: Not extensively bound.
MetabolismParacetamol: Hepatic via conjugation (glucuronidation, sulfation) and CYP450 (minor). Phenylpropanolamine: Hepatic via deamination and hydroxylation.
Half-LifeParacetamol: 1.5-3 hours. Phenylpropanolamine: 3-5 hours.
ExcretionParacetamol: Renal (mostly metabolites). Phenylpropanolamine: Renal (unchanged and metabolites).
BioavailabilityParacetamol: 60-90%. Phenylpropanolamine: ~100%.
Onset of ActionParacetamol: 30-60 min. Phenylpropanolamine: 15-30 min.
Peak Plasma TimeParacetamol: 30-60 min. Phenylpropanolamine: 1-2 hours.
Duration of ActionParacetamol: 4-6 hours. Phenylpropanolamine: 3-4 hours.

How It Works

Paracetamol: Inhibits COX enzymes centrally, reducing prostaglandin synthesis. Phenylpropanolamine: Alpha-1 adrenergic agonist causing vasoconstriction.

Mechanism Steps

1Paracetamol inhibits COX-1 and COX-2 in the CNS, reducing prostaglandin synthesis.
2Decreased prostaglandins lead to reduced pain perception and fever.
3Phenylpropanolamine activates alpha-1 adrenergic receptors on nasal blood vessels.

๐Ÿ’ก How to Take coldutch tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of coldutch tablet

โœ… Common Side Effects

  • Nausea
  • Dizziness
  • Insomnia
  • Dry mouth

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • Hypertension
  • Arrhythmias
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Agranulocytosis
  • Cerebral hemorrhage

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Hypertensive crisis
Warfarin Major Increased INR and bleeding risk
Alcohol Major Increased hepatotoxicity
Antihypertensives Moderate Reduced antihypertensive effect
Beta-blockers Moderate Hypertensive episode
Tricyclic antidepressants Moderate Enhanced sympathomimetic effect
Caffeine Minor Additive stimulation
Oral contraceptives Minor Reduced paracetamol metabolism

๐Ÿšจ Major Interactions

  • MAOIs
  • Warfarin
  • Alcohol (chronic use)

โšก Moderate Interactions

  • Antihypertensives
  • Beta-blockers
  • Tricyclic antidepressants

โ„น๏ธ Minor Interactions

  • Caffeine
  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of paracetamol.

๐Ÿท Alcohol Interaction

Chronic alcohol use increases hepatotoxicity risk of paracetamol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, severe hypertension, coronary artery disease, MAOI use, hyperthyroidism.

๐Ÿ“Š Monitoring Parameters

Liver function, blood pressure, heart rate.

๐Ÿคฑ Lactation Safety

Paracetamol safe; Phenylpropanolamine excreted in milk, use caution.

๐Ÿ’Š Overdose Management

Activated charcoal, N-acetylcysteine for paracetamol; supportive care for phenylpropanolamine.

โฐ Missed Dose

Take as soon as remembered; skip if near next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

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