coldnil 4mg tablet - Chlorpheniramine Maleate (4mg) medicine

Allermin 4mg Tablet: Complete Medicine Guide

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🏭 Universal Micro Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and urticaria.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Swelling of face, lips, tongue, or throat
  • Difficulty breathing or wheezing
  • Severe dizziness or fainting
  • Irregular or fast heartbeat
  • Confusion or hallucinations
  • Difficulty urinating or severe abdominal pain
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is coldnil 4mg tablet used for?

This medicine is an oral antihistamine containing Chlorpheniramine Maleate 4mg. It is used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes, and hives. It works by blocking histamine H1 receptors. It can cause drowsiness, so avoid driving or alcohol. Take it exactly as prescribed by your doctor.

  • Generic Name: Chlorpheniramine Maleate
  • Manufacturer: Universal Micro Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 coldnil 4mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी से होने वाले लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली, और त्वचा पर चकत्ते या खुजली को कम करने के लिए इस्तेमाल की जाती है। यह एलर्जी राइनाइटिस, पित्ती, और कीड़े के काटने से होने वाली खुजली में राहत देती है। यह दवा शरीर में हिस्टामिन नामक पदार्थ को रोककर काम करती है, जिससे एलर्जी के लक्षण कम होते हैं। इस दवा से नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, धुंधला दिखना, और पेट खराब होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव जैसे तेज धड़कन, भ्रम, या पेशाब करने में कठिनाई हो सकती है। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप से खुराक न बढ़ाएं। इस दवा से नींद आ सकती है, इसलिए गाड़ी चलाने या मशीन चलाने से बचें। शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको ग्लूकोमा, प्रोस्टेट की समस्या, दिल की बीमारी, या लीवर या किडनी की बीमारी है तो डॉक्टर को बताएं। बच्चों को डॉक्टर की सलाह के बिना यह दवा न दें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 coldnil 4mg tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal itching caused by seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives associated with acute or chronic urticaria.","evidence":"Well-established"},{"condition":"Itching due to insect bites","description":"Provides relief from localized itching and mild allergic skin reactions after insect bites.","evidence":"Well-established"},{"condition":"Common cold","description":"May help reduce runny nose and sneezing in colds, but it does not treat the infection itself.","evidence":"Limited"},{"condition":"Anaphylaxis adjunct","description":"Used as an add-on after epinephrine in emergency treatment of anaphylaxis, but never as a replacement for epinephrine.","evidence":"Limited"}]

Off-label uses: [{"condition":"Insomnia","description":"Sometimes used off-label for short-term sleep aid due to its sedative effect, but this is not a recommended primary use.","evidence":"Limited"},{"condition":"Motion sickness","description":"Occasionally used off-label to prevent nausea and vomiting associated with motion sickness.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Urticaria, Insect bite itching, Common cold

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate
Brand NameAllermin
ManufacturerUniversal Micro Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassH1 Antihistaminics (First Generation)
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk if it upsets your stomach.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding, bruising, or severe drowsiness immediately.
7
Tell your doctor about all other medicines you are taking, especially sedatives and antidepressants.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
Itchy skin or hives
This medicine is used for urticaria and itching.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary
Chest pain
This medicine is not for chest pain; seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration. Food may slightly delay absorption but does not significantly reduce the total amount absorbed.
DistributionThis medicine is widely distributed throughout body tissues and fluids, including the central nervous system because it is lipophilic.
Protein BindingApproximately 70% bound to plasma proteins.
MetabolismThis medicine is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6 and CYP3A4.
Half-LifeThe elimination half-life of this medicine is approximately 12 to 43 hours in adults, with an average of about 20 hours.
ExcretionThis medicine and its metabolites are mainly excreted in the urine.
BioavailabilityThe oral bioavailability of this medicine is approximately 25% to 50% due to first-pass metabolism.
Onset of ActionThe onset of action of this medicine is usually within 30 to 60 minutes after oral intake.
Peak Plasma TimeThe peak plasma concentration of this medicine is reached in about 2 to 6 hours after oral administration.
Duration of ActionThe duration of action of this medicine is typically 4 to 6 hours, but drowsiness may last longer.

How It Works

This medicine works by competitively blocking histamine H1 receptors on cells in the respiratory tract, blood vessels, and skin. Histamine is a chemical released during allergic reactions that causes sneezing, itching, watery eyes, and runny nose. By blocking H1 receptors, this medicine reduces these allergic symptoms. It also has some anticholinergic and sedative effects because it can cross into the brain.

Mechanism Steps

1
Histamine release: During an allergic reaction, immune cells release histamine into the bloodstream and tissues.
2
H1 receptor binding: This medicine binds to histamine H1 receptors on target cells, preventing histamine from attaching.
3
Reduced allergic response: Blocking H1 receptors reduces sneezing, itching, runny nose, and other allergic symptoms.
4
Central nervous system effects: This medicine crosses the blood-brain barrier and causes drowsiness by affecting brain histamine receptors.

💡 How to Take coldnil 4mg tablet

Strength: Each tablet contains Chlorpheniramine Maleate 4mg.

1Take this medicine by mouth with a glass of water.
2You may take it with or without food. If it upsets your stomach, take it with food or milk.
3Swallow the tablet whole. Do not crush or chew unless your doctor advises.
4Take it at the same times each day if your doctor has prescribed a regular schedule.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 4mg every 4 to 6 hours as needed for allergic symptoms. The maximum recommended dose is 24mg in 24 hours. However, the dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, confusion, and dry mouth. A lower dose may be recommended by your doctor. Use with caution.
Renal ImpairmentDose adjustment may be needed in patients with kidney disease. Consult your doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be needed in patients with liver disease. Consult your doctor for individualized dosing.
Maximum Daily Dose24mg per day for adults.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and dizziness.
Grapefruit juice
Use with caution
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of coldnil 4mg tablet

✅ Common Side Effects

Drowsiness (Common (more than 10%))
Avoid driving or operating machinery. If drowsiness is excessive, consult your doctor.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugar-free gum. Consult doctor if it becomes bothersome.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid sudden movements.
Blurred vision (Uncommon (1-5%))
Avoid tasks requiring clear vision until it resolves. Consult doctor if persistent.
Upset stomach (Uncommon (1-5%))
Take with food or milk to reduce stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (less than 0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
Irregular heartbeat (Rare (less than 0.1%))
Contact your doctor immediately if you feel palpitations, chest pain, or shortness of breath.
Confusion or hallucinations (Rare (less than 0.1%))
Stop the medicine and seek medical attention if you experience confusion, hallucinations, or unusual behavior.
Difficulty urinating (Rare (less than 0.1%))
Consult your doctor if you have trouble passing urine or experience lower abdominal pain.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bleeding, bruising, or persistent fever to your doctor.
Liver dysfunction
Seek medical advice if you notice yellowing of skin or eyes, dark urine, or severe fatigue.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Alcohol Major
Benzodiazepines Major
Tricyclic antidepressants Moderate
Fluoxetine Moderate
Paroxetine Moderate
Atropine Moderate
Caffeine Minor
Antacids Minor
Opioid pain relievers Major

🚨 Major Interactions

  • MAO inhibitors
  • Alcohol
  • Other central nervous system depressants (e.g., benzodiazepines, opioids, sleep aids)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Avoid drinking alcohol while taking this medicine. Alcohol increases the drowsiness and dizziness caused by this medicine and can impair your ability to drive or operate machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to chlorpheniramine or other antihistamines of similar structure","Narrow-angle glaucoma","Urinary retention","Severe liver disease","Newborns and premature infants","Breastfeeding without medical advice"]

⚠️ Warnings & Precautions

["May cause drowsiness. Avoid driving or operating machinery until you know how this medicine affects you.","Avoid alcohol and other central nervous system depressants.","Use with caution in patients with glaucoma, prostate enlargement, or difficulty urinating.","Use with caution in patients with heart disease, thyroid disease, or kidney disease.","Do not use for longer than recommended without medical supervision.","Keep out of reach of children.","Elderly patients may be more sensitive to side effects such as drowsiness and confusion."]

🤱 Lactation Safety

This medicine may pass into breast milk and could cause drowsiness in a nursing infant. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek emergency medical attention immediately. Symptoms of overdose may include severe drowsiness, confusion, hallucinations, irregular heartbeat, seizures, or difficulty breathing. Treatment is supportive and symptomatic. Do not try to treat yourself at home.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Avoid driving or operating heavy machinery until you know how this medicine affects you, because it can cause drowsiness. Avoid drinking alcohol while taking this medicine, as it can increase drowsiness and dizziness. Tell your doctor if you have glaucoma, prostate problems, thyroid disease, heart disease, or liver or kidney disease before taking this medicine. Do not use this medicine for longer than your doctor recommends without a follow-up. Keep this medicine out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, confusion, dry mouth, and urinary retention. A lower dose may be recommended. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not fully established.

🏥 Post-Surgery Considerations

This medicine may cause drowsiness and dry mouth, which can affect recovery after surgery. Inform your surgeon and anesthesiologist if you are taking this medicine. It may interact with other medications used during surgery.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental problems. Inform your dentist if you are taking this medicine. It may also interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergens that trigger your symptoms.
🥗
Keep windows closed during high pollen seasons.
😴
Use air purifiers to reduce indoor allergens.
💧
Maintain good hydration to reduce dry mouth.
🧘
Get adequate sleep to support immune health.

🏋️ Exercise Considerations

This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how it affects you. If you exercise outdoors, be aware of allergen exposure.

🥗 Diet Recommendations

Include foods rich in vitamin C to support immune health.
Stay well hydrated to reduce dry mouth.
Avoid alcohol and caffeine if they worsen your symptoms.
Eat a balanced diet to support overall health.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring alertness. It is best to take it when you do not need to be fully alert, such as at bedtime. Discuss with your doctor if your work requires you to be alert.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop suddenly if you have been taking it regularly for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance, increased drowsiness, and anticholinergic effects such as dry mouth and constipation. Regular monitoring by your doctor is recommended if used for more than a few weeks. Do not use it continuously without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Avoiding known allergens can reduce the need for medication.

Evidence: Well-established
Nasal saline irrigation

Can help relieve nasal congestion and allergy symptoms.

Evidence: Well-established
Second-generation antihistamines

May cause less drowsiness and are often preferred for daytime use.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. You can receive vaccinations while taking this medicine, but inform your healthcare provider.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue your regular dosing schedule as advised by your doctor. Check local customs regulations for carrying medicines. Do not leave it in a hot car or checked luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with seasonal allergic rhinitis
She started this medicine as prescribed for sneezing and runny nose during spring. Within an hour, her symptoms improved significantly. She experienced mild drowsiness, so she took it at bedtime. She was advised to avoid driving after taking it.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while still providing allergy relief.
👤 A 45-year-old man with chronic urticaria
He was prescribed this medicine for itching and hives. He noticed relief within 30 minutes of taking the tablet. He was advised to avoid alcohol and to take it with food to prevent stomach upset. He reported no serious side effects.
💡 Lesson: This medicine effectively relieves itching and hives, but it should be taken with food and alcohol should be avoided.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking it.

Q: Can I take it with other allergy medicines?

A: Do not take other antihistamines without consulting your doctor, as it may increase side effects.

Q: Is it safe to take every day?

A: It can be taken daily for short periods as prescribed. Long-term use should be monitored by your doctor.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for coldnil 4mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure allergies permanently.
    Fact: This medicine only relieves symptoms; it does not cure allergies.
  • Myth: It is safe to take this medicine with alcohol.
    Fact: Alcohol increases drowsiness and should be avoided.
  • Myth: This medicine is safe for newborns.
    Fact: This medicine is not recommended for newborns and premature infants.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine Maleate 4mg tablet

Brand Alternatives

  • Allermin 4mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Chlorpheniramine","class":"First-generation antihistamine","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine","class":"Second-generation antihistamine","sedation":"Low","duration":"24 hours"},{"medicine":"Loratadine","class":"Second-generation antihistamine","sedation":"Low","duration":"24 hours"}]

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