Acolate Plus Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe headache with visual changes
- Chest pain or palpitations
- Blood in vomit or stool
- Decreased urine output
- Severe dizziness or fainting
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is coldgard-plus tablet used for?
This medicine is a combination of levocetirizine (antihistamine) and phenylephrine (decongestant) used to treat symptoms of allergic rhinitis and common cold, such as sneezing, runny nose, and nasal congestion. It is usually taken once or twice daily as prescribed.
- Generic Name: Levocetirizine + Phenylephrine
- Manufacturer: Santo Formulations
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coldgard-plus tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसेटिरिज़िन और फेनाइलएफ्रिन का संयोजन है, जिसका उपयोग एलर्जी राइनाइटिस और सामान्य सर्दी के लक्षणों जैसे छींक, नाक बहना, नाक बंद होना और आंखों में खुजली को कम करने के लिए किया जाता है। यह दवा डॉक्टर के परामर्श से ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में हल्की नींद आना, मुंह सूखना, सिरदर्द और थकान शामिल हैं। कुछ लोगों को मतली, चक्कर आना या दिल की धड़कन तेज होना भी महसूस हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या तेज धड़कन हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। निर्धारित मात्रा से अधिक न लें। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। इस दवा के साथ शराब न पिएं। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड या गुर्दे की बीमारी है, तो अपने डॉक्टर को बताएं। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।
💊 coldgard-plus tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from nasal congestion, sneezing, and runny nose due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Allergic conjunctivitis","description":"Helps reduce itching, redness, and tearing of the eyes caused by allergies.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to relieve nasal congestion associated with sinusitis, though not a primary treatment.","evidence":"Limited"},{"condition":"Eustachian tube dysfunction","description":"May be used off-label to reduce congestion and improve ear pressure equalization.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Allergic conjunctivitis, Sinusitis
📋 Drug Information
| Generic Name(s) | Levocetirizine + Phenylephrine |
| Brand Name | Allercet Cold Tablet |
| Manufacturer | Santo Formulations |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Levocetirizine selectively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, and runny nose. Phenylephrine stimulates alpha-1 adrenergic receptors on blood vessels in the nasal mucosa, causing vasoconstriction and reducing swelling and congestion.
Mechanism Steps
💡 How to Take coldgard-plus tablet
Strength: Each tablet contains Levocetirizine 5 mg and Phenylephrine 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily as prescribed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially drowsiness and cardiovascular effects. Use with caution and lower doses may be considered. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. Levocetirizine dose should be reduced based on creatinine clearance. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Use with caution in severe liver disease. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily. Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coldgard-plus tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Beta-blockers | Moderate | |
| CNS depressants | Moderate | |
| Anticholinergics | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Beta-blockers
- Central nervous system depressants
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness caused by levocetirizine and may worsen dizziness. It can also increase the risk of stomach upset.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to levocetirizine, phenylephrine, or any component of the formulation","Severe hypertension","Coronary artery disease","Hyperthyroidism","Concurrent use with monoamine oxidase inhibitors (MAOIs)","Narrow-angle glaucoma","Urinary retention"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use with alcohol or other CNS depressants.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, or thyroid disorders.","Do not exceed recommended dose; high doses of phenylephrine can cause severe hypertension.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever.","Not recommended for children under 12 years without medical advice."]
🤱 Lactation Safety
Levocetirizine is excreted in breast milk in small amounts. Phenylephrine may reduce breast milk production. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, hypertension, palpitations, or seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not drink alcohol while taking this medicine as it can increase drowsiness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, or kidney disease. Do not use this medicine for more than 7 days without consulting your doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and cardiovascular effects of this medicine. Use with caution, and lower doses may be considered. Monitor blood pressure and heart rate regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy or are pregnant. Levocetirizine is generally considered safe, but phenylephrine should be used with caution.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and affect blood pressure.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental caries. It may also interact with local anesthetics containing epinephrine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise like walking may be safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience severe side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of phenylephrine can lead to rebound congestion and increased blood pressure. Levocetirizine may cause tolerance. Regular monitoring of blood pressure and renal function is advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps clear nasal passages and reduce congestion without medication.
Evidence: Well-establishedReducing exposure to allergens can prevent allergic rhinitis symptoms.
Evidence: Well-establishedEffective for moderate to severe allergic rhinitis, but require prescription.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are unwell with a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Levocetirizine starts working within 1 hour, while phenylephrine may take 15-30 minutes to relieve nasal congestion.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you.
A: No, avoid alcohol as it can increase drowsiness and other side effects.
A: This medicine is for short-term use. Do not use for more than 7 days without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for coldgard-plus tablet
View AllAlternative brands with exact same active ingredient:
-
levo setride cold total tabletWockhardt Ltd ₹15.00 55.9% CHEAPER
-
leforin pp tabletForein Life Sciences Pvt Ltd ₹30.00 11.8% CHEAPER
-
berrycold tabletBayberry Pharmaceuticals Pvt Ltd ₹33.00 2.9% CHEAPER
-
coldorest tabletAdept Biocare ₹34.00 SAME PRICE
-
lecen cold 5mg/5mg/325mg tabletEncyclo Healthcare ₹34.00 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure allergies permanently.
Fact: This medicine provides symptomatic relief but does not cure allergies. Allergies require long-term management. - Myth: It is safe to take this medicine for months.
Fact: This medicine is intended for short-term use. Prolonged use should be under medical supervision. - Myth: More tablets will give faster relief.
Fact: Taking more than the recommended dose can cause serious side effects like high blood pressure and severe drowsiness.
🔄 Alternative Options
Generic Alternatives
- Levocetirizine + Phenylephrine tablets
Brand Alternatives
- Acolate Plus Tablet