Albicold Tablet: Complete Medicine Guide for Patients
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Fast, irregular, or pounding heartbeat.
- Seizures or convulsions.
- Severe confusion, hallucinations, or agitation.
- Inability to pass urine or severe lower abdominal pain.
- Yellowing of the skin or eyes, or dark urine.
- Severe drowsiness that interferes with breathing or consciousness.
If experiencing severe symptoms, call emergency services immediately.
What is coldfienz tablet used for?
This medicine is a combination of caffeine 25 mg and diphenhydramine 25 mg used for short-term relief of allergy symptoms such as sneezing, runny nose, and itchy eyes. Diphenhydramine blocks histamine to reduce allergy symptoms, while caffeine helps counter drowsiness. It should be taken exactly as directed and avoided in certain medical conditions.
- Generic Name: Caffeine + Diphenhydramine
- Manufacturer: Plena Remedies
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 coldfienz tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैफीन 25 मिलीग्राम और डाइफेनहाइड्रामाइन 25 मिलीग्राम का संयोजन है, जिसका उपयोग एलर्जी के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली और पानी आना, और त्वचा पर खुजली वाले दाने के अल्पकालिक उपचार के लिए किया जाता है। डाइफेनहाइड्रामाइन हिस्टामिन को रोककर एलर्जी के लक्षणों को कम करता है, जबकि कैफीन नींद और सुस्ती को कुछ हद तक कम करने में मदद करता है। यह दवा केवल डॉक्टर की सलाह पर और निर्देशित अवधि तक ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, धुंधली दृष्टि, और पेट में हल्की गड़बड़ी शामिल हैं। कुछ लोगों को कैफीन के कारण बेचैनी, घबराहट, दिल की धड़कन तेज होना, या नींद न आने की समस्या हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन तेज दिल की धड़कन, दौरे, भ्रम, या गंभीर एलर्जी प्रतिक्रिया हो सकती है। यदि कोई भी दुष्प्रभाव गंभीर या लगातार बना रहे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें और निर्धारित मात्रा से अधिक न लें। इसमें डाइफेनहाइड्रामाइन होने के कारण शराब और अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें, क्योंकि इससे अत्यधिक नींद और सांस लेने में कठिनाई हो सकती है। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। यदि आपको ग्लूकोमा, पेशाब में रुकावट, दिल की बीमारी, उच्च रक्तचाप, या लीवर या किडनी की बीमारी है, तो इस दवा को लेने से पहले डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इस दवा का सेवन न करें।
💊 coldfienz tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"This medicine provides short-term relief of sneezing, runny nose, itchy nose, and watery eyes associated with seasonal or perennial allergies, with caffeine added to reduce daytime drowsiness.","evidence":"Established for diphenhydramine; caffeine component is used to counter sedation."},{"condition":"Urticaria (hives)","description":"Diphenhydramine in this medicine helps reduce itching and skin wheals in mild acute urticaria, while caffeine may help maintain alertness during the day.","evidence":"Established for diphenhydramine."},{"condition":"Common cold with allergic symptoms","description":"This medicine may be used for temporary relief of runny nose, sneezing, and itchy throat when these symptoms are driven by histamine release, though it does not treat the underlying viral infection.","evidence":"Supportive for symptom relief only."},{"condition":"Motion sickness","description":"Diphenhydramine can help prevent nausea and vomiting associated with motion sickness, and caffeine may help offset sedation, but this combination is not a first-line choice for everyone.","evidence":"Established for diphenhydramine; combination evidence is limited."},{"condition":"Insomnia (short-term)","description":"Diphenhydramine is sometimes used for occasional sleeplessness, but the caffeine content in this medicine may work against sleep, so it is not an ideal choice for this purpose.","evidence":"Conflicting due to caffeine content."}]
Off-label uses: [{"condition":"Adjunct for mild anxiety-related itching","description":"Sometimes used when itching has a strong central component, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Prevention of nausea in mild vestibular disturbance","description":"Diphenhydramine may be used off-label for nausea related to inner ear problems, but caffeine can worsen palpitations in some patients.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Urticaria, Common cold with allergic symptoms, Motion sickness
📋 Drug Information
| Generic Name(s) | Caffeine + Diphenhydramine |
| Brand Name | Anti Cold Tablet |
| Manufacturer | Plena Remedies |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + CNS Stimulant |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C, away from direct sunlight, moisture, and heat. Keep it in the original container with the lid tightly closed. Do not store it in the bathroom or near the kitchen sink. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture, depending on the manufacturer's packaging. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with opposing but complementary effects. Diphenhydramine is a first-generation antihistamine that competitively blocks histamine H1 receptors in the central nervous system and peripheral tissues, reducing allergy symptoms and causing sedation. Caffeine is a methylxanthine that antagonizes adenosine A1 and A2A receptors in the brain, which increases alertness and reduces the drowsiness produced by diphenhydramine. Together, the combination aims to relieve allergic symptoms while partially offsetting sedation, although individual responses vary widely.
Mechanism Steps
💡 How to Take coldfienz tablet
Strength: Immediate-release oral tablet containing caffeine 25 mg and diphenhydramine 25 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally every 4 to 6 hours as needed for symptom relief, not to exceed the maximum daily dose stated on the package or prescribed by your clinician. Because this medicine contains diphenhydramine and caffeine, the dose must be individualized by a qualified clinician based on your age, weight, medical history, kidney and liver function, and other medicines you are taking. Do not take more than the recommended dose, and do not use it for more than a few days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for newborns or premature infants, and it should not be given to children without a doctor's advice. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects of diphenhydramine and to the stimulant effects of caffeine. The dose should be individualized by a clinician, and lower doses are often recommended. Elderly patients should be monitored for confusion, falls, urinary retention, and cardiac effects. |
| Renal Impairment | Patients with kidney disease may have prolonged elimination of diphenhydramine and caffeine. The dose should be individualized by a clinician, and caution is advised. In severe renal impairment, this medicine should be avoided unless specifically recommended by a clinician. |
| Hepatic Impairment | Patients with liver disease may have reduced metabolism of both diphenhydramine and caffeine, leading to higher blood levels and increased side effects. The dose should be individualized by a clinician, and this medicine should be avoided in severe liver disease. |
| Maximum Daily Dose | The maximum daily dose should not exceed the limit recommended by your clinician or the product label. As a general educational reference, the maximum daily dose of diphenhydramine for adults is usually 300 mg, and the maximum daily dose of caffeine from this medicine should be kept low to avoid stimulant side effects. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of coldfienz tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| CYP2D6 inhibitors (fluoxetine, paroxetine, quinidine) | Moderate | |
| CYP1A2 inhibitors (ciprofloxacin, fluvoxamine) | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Beta-agonists (salbutamol) | Moderate | |
| Theophylline | Moderate | |
| Oral contraceptives | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol
- Other sedating antihistamines, benzodiazepines, opioids, or sleeping pills
- CYP2D6 inhibitors such as fluoxetine, paroxetine, or quinidine
- CYP1A2 inhibitors such as ciprofloxacin, fluvoxamine, or ketoconazole
⚡ Moderate Interactions
- Tricyclic antidepressants
- Anticholinergic medicines such as oxybutynin or benztropine
- Beta-agonists such as salbutamol
- Theophylline
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Diphenhydramine and alcohol both depress the central nervous system, and combining them can cause excessive sedation, impaired coordination, difficulty breathing, and dangerous drops in blood pressure. Caffeine does not counteract these effects and may mask the level of impairment, leading to risky behavior. If you have consumed alcohol, wait until it has fully cleared from your system before taking this medicine, and never use alcohol to manage the sedative effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to diphenhydramine, caffeine, or any component of this medicine","Untreated narrow-angle glaucoma","Urinary retention or bladder neck obstruction","Severe liver disease","Uncontrolled hypertension or severe cardiovascular disease","Use in newborns and premature infants","Concurrent use with monoamine oxidase inhibitors"]
⚠️ Warnings & Precautions
["This medicine may cause drowsiness and impair your ability to drive or operate machinery.","Avoid alcohol and other central nervous system depressants while taking this medicine.","Do not use for longer than directed without medical advice.","Use with caution in elderly patients, who are more sensitive to sedation and anticholinergic effects.","Use with caution in patients with asthma, increased intraocular pressure, hyperthyroidism, or cardiovascular disease.","Do not exceed the recommended dose; high doses can cause serious cardiac and neurological effects.","Keep out of reach of children; accidental overdose can be dangerous."]
🤱 Lactation Safety
Diphenhydramine passes into breast milk and may cause drowsiness or irritability in a breastfed infant. Caffeine also passes into breast milk and can accumulate in the infant, especially with repeated maternal use. Breastfeeding mothers should avoid this medicine or use it only under close medical supervision, and they should watch the infant for excessive sleepiness, poor feeding, or unusual fussiness.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, confusion, hallucinations, seizures, irregular heartbeat, and difficulty breathing. If you suspect an overdose, seek emergency medical care immediately. Do not try to induce vomiting unless instructed by a medical professional. Treatment is supportive and may include activated charcoal, intravenous fluids, and management of seizures or arrhythmias. Bring the medicine container or a list of ingredients to the hospital so that the medical team can provide appropriate care.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided it is not almost time for your next dose. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, contact your clinician or pharmacist for advice.
Additional Safety Advice
Take this medicine exactly as directed by your clinician and do not exceed the recommended dose. Because it contains diphenhydramine, avoid alcohol and other sedating medicines such as benzodiazepines, sleeping pills, or opioid painkillers, as the combination can cause excessive drowsiness and slowed breathing. Do not drive, cycle, or operate heavy machinery until you are sure this medicine does not impair your alertness. If you have glaucoma, an enlarged prostate, difficulty passing urine, asthma, heart disease, high blood pressure, thyroid problems, or liver or kidney disease, tell your clinician before using this product. Do not use this medicine for more than a few days without medical advice, and keep it out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, speak to a clinician before taking this medicine. Store it at room temperature, away from moisture and direct sunlight, and check the expiry date before each use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of diphenhydramine, which can cause confusion, falls, urinary retention, and constipation. The caffeine component can increase heart rate and blood pressure. Lower doses are often recommended, and this medicine should be used with caution under medical supervision. Regular monitoring for side effects is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor before use. Diphenhydramine is generally considered acceptable for short-term use in pregnancy when needed, but caffeine intake should be limited. This combination product should be avoided in pregnancy unless specifically recommended by a clinician after weighing the benefits and risks.
🏥 Post-Surgery Considerations
After surgery, this medicine should be used with caution because it can cause drowsiness and interact with anesthetics and pain medicines. Inform your surgeon and anesthesiologist about all medicines you are taking before surgery. Do not take this medicine after surgery without your doctor's approval, as it may interfere with recovery and increase the risk of complications.
🦷 Dental Procedures
Before dental procedures, inform your dentist about this medicine. Diphenhydramine can cause dry mouth, which may increase the risk of dental problems, and it can interact with sedatives used during dental procedures. Caffeine can increase heart rate and blood pressure. Your dentist may recommend adjusting the dose or timing of this medicine before a procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your coordination. Avoid strenuous exercise, heavy lifting, or activities that require balance until you know how the medicine affects you. If you feel dizzy or weak, stop exercising and rest. Stay hydrated, especially if you are active, because dry mouth and increased heart rate can be worsened by dehydration.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to work, drive, or operate machinery. Avoid driving or operating heavy machinery until you know how it affects you. If your job requires alertness, discuss with your doctor whether this medicine is appropriate or if a less sedating alternative would be better. The caffeine component may help some people stay alert, but it can also cause jitteriness or insomnia, which may affect work performance.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within a few days, if they worsen, or if you experience any serious side effects such as irregular heartbeat, seizures, severe drowsiness, or difficulty breathing. Do not stop suddenly if you have been taking it regularly for a long time without medical advice, as your doctor may need to adjust your treatment plan.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of diphenhydramine can lead to tolerance, dependence, and increased risk of cognitive side effects, especially in older adults. Chronic caffeine use can cause insomnia, nervousness, and palpitations. Regular monitoring by a clinician is advised if long-term use is necessary, and alternative treatments should be considered.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to allergens such as pollen, dust mites, and pet dander can help prevent allergy symptoms.
Evidence: Well-establishedRinsing the nasal passages with saline can help relieve congestion and allergy symptoms.
Evidence: Well-establishedMedicines such as cetirizine, loratadine, or fexofenadine can relieve allergy symptoms with less drowsiness.
Evidence: Well-establishedThese sprays reduce inflammation in the nasal passages and are effective for allergic rhinitis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a vaccine, inform your healthcare provider about all medicines you are taking. If you have an allergic reaction to a vaccine, this medicine may be used to treat mild symptoms, but severe reactions require emergency care.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container with the lid tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom or near the kitchen sink.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription or a copy of the prescription. Keep it in your hand luggage if you need it during the flight, and store it at room temperature away from direct sunlight and moisture. If you are crossing time zones, continue taking the medicine according to the schedule advised by your doctor, but avoid taking it late in the day if it interferes with sleep. Check the customs regulations of your destination country regarding medicines containing diphenhydramine and caffeine, and carry a doctor's note if you are carrying a large quantity.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts to work within 15 to 30 minutes, with peak effects within 1 to 4 hours. The antihistamine effect lasts about 4 to 6 hours.
A: This medicine is intended for short-term use. Do not take it every day for more than a few days without consulting your doctor.
A: Diphenhydramine can cause drowsiness, but the caffeine in this medicine may partially offset it. Individual responses vary, so avoid driving until you know how it affects you.
A: Do not take it with other antihistamines or sedating medicines without consulting your doctor, as the effects can add up.
A: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for coldfienz tablet
View AllAlternative brands with exact same active ingredient:
-
constyl tabletLezaa Biotech ₹33.00 7.4% CHEAPER
-
albicold tabletAlbia Biocare ₹42.19 18.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for everyone. It should be avoided in people with certain eye, urinary, heart, and liver conditions, and in newborns. - Myth: Caffeine in this medicine makes it completely non-drowsy.
Fact: Caffeine only partially offsets the sedative effect of diphenhydramine. Many people still feel drowsy and should not drive until they know how it affects them. - Myth: You can take this medicine for as long as you want.
Fact: This medicine is intended for short-term use. Prolonged use without medical advice can lead to tolerance, dependence, and increased side effects. - Myth: It is safe to drink alcohol with this medicine.
Fact: Alcohol should be avoided completely because it adds to the sedative effects and can cause dangerous drowsiness and breathing problems.
🔄 Alternative Options
Generic Alternatives
- Caffeine 25 mg + Diphenhydramine 25 mg tablet
Brand Alternatives
- Albicold Tablet