Afex Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in sputum or vomit
- Severe chest pain or difficulty breathing
- Irregular or rapid heartbeat
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is afex tablet used for?
This medicine is a combination of Terbutaline and Bromhexine used to treat bronchospasm and thick mucus in conditions like asthma and bronchitis. It works by relaxing airway muscles and thinning mucus.
- Generic Name: Terbutaline + Bromhexine
- Manufacturer: Eden Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 afex tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टर्ब्यूटलीन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग अस्थमा, ब्रोंकाइटिस और अन्य श्वसन संबंधी समस्याओं में सांस लेने में कठिनाई और बलगम को कम करने के लिए किया जाता है। यह वायुमार्ग की मांसपेशियों को आराम देकर और बलगम को पतला करके काम करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कंपन, घबराहट, सिरदर्द, धड़कन बढ़ना और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सीने में दर्द, सांस लेने में तकलीफ, या एलर्जी की प्रतिक्रिया हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड या गुर्दे/यकृत की समस्या है तो डॉक्टर को बताएं। इस दवा के साथ शराब न लें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 afex tablet Uses & Benefits
[{"condition":"Bronchial asthma","description":"Used to relieve bronchospasm and facilitate breathing in patients with asthma.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Helps in loosening mucus and relieving cough in acute and chronic bronchitis.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Provides symptomatic relief by relaxing airways and thinning mucus.","evidence":"Moderate"},{"condition":"Productive cough","description":"Aids in clearing thick mucus from the respiratory tract.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]
Primary treatment for: Bronchial asthma
Also treats: Bronchitis, COPD, Productive cough
📋 Drug Information
| Generic Name(s) | Terbutaline + Bromhexine |
| Brand Name | Askafex TR Suspension |
| Manufacturer | Eden Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator + Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic receptor agonist that binds to beta-2 receptors on bronchial smooth muscle, leading to relaxation and bronchodilation. Bromhexine is a mucolytic agent that reduces the viscosity of mucus by depolymerizing mucopolysaccharide fibers, thereby facilitating its expulsion from the respiratory tract.
Mechanism Steps
💡 How to Take afex tablet
Strength: Each tablet contains Terbutaline 2.5 mg and Bromhexine 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times a day, or as directed by your physician. The dose may vary depending on the severity of the condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Use with caution and dose adjustment may be required. Consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (7.5 mg terbutaline and 12 mg bromhexine) in divided doses. Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of afex tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Furosemide | Moderate | |
| Corticosteroids | Moderate | |
| Theophylline | Moderate | |
| Digoxin | Minor | |
| Anticholinergics | Minor |
🚨 Major Interactions
- Non-selective beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Xanthine derivatives (e.g., theophylline)
🍷 Alcohol Interaction
Alcohol may increase the sedative effects and cardiovascular side effects of this medicine. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to terbutaline, bromhexine, or any component of the formulation","Severe cardiovascular disease","Hyperthyroidism","Diabetes mellitus (uncontrolled)","Severe hepatic or renal impairment"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease, including coronary insufficiency, arrhythmias, and hypertension.","May cause hypokalemia; monitor potassium levels, especially in patients on diuretics or corticosteroids.","May cause tremors and nervousness; advise patients to avoid driving or operating machinery if affected.","Not recommended for use in children under 12 years without medical advice.","Do not exceed the recommended dose.","Consult a doctor if symptoms persist or worsen."]
🤱 Lactation Safety
Terbutaline is excreted in breast milk in small amounts. Bromhexine is also likely excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe tachycardia, tremors, palpitations, hypokalemia, and hypotension. Seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and electrolyte levels.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease. Avoid alcohol while taking this medicine as it may increase drowsiness and heart rate. Do not drive or operate heavy machinery if you feel dizzy or shaky. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the cardiovascular effects of this medicine. Use with caution and monitor heart rate and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain anesthetic agents.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth or interact with certain dental medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you experience tremors, palpitations, or dizziness after taking this medicine. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause tremors or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause nervousness, which can impact your concentration.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise you on whether to stop or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine should be monitored by a doctor. It may cause tremors, palpitations, and hypokalemia. Regular monitoring of heart rate, blood pressure, and potassium levels may be required. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help loosen mucus and ease breathing.
Evidence: LimitedHelps clear mucus from airways.
Evidence: ModerateReducing exposure to allergens and pollutants can help prevent symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Consult your doctor about vaccinations, especially influenza and pneumococcal vaccines, which are recommended for patients with respiratory conditions.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust your dosing schedule accordingly, but consult your doctor for specific advice. Keep enough supply for your trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to an hour after taking it. However, the full effect may take a few hours.
A: Inform your doctor about all other medicines you are taking, as this medicine can interact with certain drugs like beta-blockers, MAOIs, and diuretics.
A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed and prescribed.
🤔 Common Patient Concerns
🔄 Substitutes for afex tablet
View AllAlternative brands with exact same active ingredient:
-
terfex tabletEskag Pharma Pvt Ltd ₹23.68 261% COSTLIER
-
terbet 2.5 mg/4 mg tabletStrassenburg Pharmaceuticals.Ltd ₹41.44 531.7% COSTLIER
-
Terfex SyrupEskag Pharma Pvt Ltd ₹65.63 900.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure asthma.
Fact: This medicine provides symptomatic relief but does not cure asthma. It should be used as part of a comprehensive treatment plan. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the prescribed dose can lead to serious side effects. Always follow your doctor's instructions.
🔄 Alternative Options
Generic Alternatives
- Terbutaline + Bromhexine combination tablets from other manufacturers
Brand Alternatives
- Afex Tablet