cocarni 500mg tablet - Levo-carnitine (500mg) medicine

cocarni 500mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Merril Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is cocarni 500mg tablet used for?

Acylcar Tablet (Levo-carnitine) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Levo-carnitine (500mg), which Acts as a carrier molecule for long-chain fatty acids across the inner mitochond. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Levo-carnitine
  • Manufacturer: Merril Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cocarni 500mg tablet Uses & Benefits

Primary and secondary carnitine deficiency, chronic fatigue syndrome, heart failure, peripheral vascular disease, hemodialysis-associated carnitine deficiency.

Off-label uses: Male infertility, athletic performance enhancement, Alzheimer's disease.

๐Ÿ“‹ Drug Information

Generic Name(s)Levo-carnitine
Brand NameAcylcar Tablet
ManufacturerMerril Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassAmino acids
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed via active transport in the small intestine; bioavailability is dose-dependent.
DistributionDistributes widely in tissues, especially heart and skeletal muscle; crosses placenta and enters breast milk.
Protein BindingMinimal (less than 10%)
MetabolismPartially metabolized in the liver to acyl esters.
Half-Life17.4 hours (oral)
ExcretionRenal excretion as unchanged drug and metabolites.
Bioavailability5-18% (oral); higher with intravenous administration.
Onset of ActionWithin 1-2 hours (oral)
Peak Plasma Time3-6 hours (oral)
Duration of ActionUp to 24 hours

How It Works

Acts as a carrier molecule for long-chain fatty acids across the inner mitochondrial membrane, facilitating beta-oxidation and energy production.

Mechanism Steps

1Levo-carnitine is transported into cells via OCTN2 transporters.
2Inside cells, it forms acyl-carnitine esters with long-chain fatty acids via carnitine palmitoyltransferase I (CPT-I).
3Acyl-carnitine is shuttled across the inner mitochondrial membrane by carnitine-acylcarnitine translocase.

๐Ÿ’ก How to Take cocarni 500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cocarni 500mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Fishy body odor

๐Ÿšจ Serious Side Effects

  • Seizures (in patients with pre-existing seizure disorders)

โš ๏ธ Rare Side Effects

  • Allergic reactions
  • Rash

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to enhanced anticoagulant effect.
Acenocoumarol Major Increased bleeding risk.
Thyroid hormones Moderate May reduce carnitine levels.
Valproic acid Moderate May cause carnitine deficiency.
Antacids Minor May reduce absorption of carnitine.
Calcium supplements Minor May reduce absorption of carnitine.

๐Ÿšจ Major Interactions

  • Warfarin
  • Acenocoumarol

โšก Moderate Interactions

  • Thyroid hormones
  • Valproic acid

โ„น๏ธ Minor Interactions

  • Antacids
  • Calcium supplements

๐Ÿฝ๏ธ Food Interactions

High-fat meals may reduce absorption; dairy products may decrease bioavailability.

๐Ÿท Alcohol Interaction

No significant interaction reported.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to carnitine or any component.

๐Ÿ“Š Monitoring Parameters

Plasma carnitine levels, renal function, signs of bleeding if on anticoagulants.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

May cause diarrhea; supportive care.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cocarni 500mg tablet

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Alternative brands with exact same active ingredient (Levo-carnitine (500mg)):

Medical Note: Always consult your doctor before switching medications.

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