acylcar tablet - Levo-carnitine (500mg) medicine

Carnisure 500 Tablet (Levo-carnitine 500mg): Complete Guide

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for primary and secondary carnitine deficiency; limited for off-label uses.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Seizures or convulsions
  • Difficulty breathing or swelling of face, lips, or throat
  • Severe abdominal pain or persistent vomiting
  • Confusion or unusual weakness
  • Signs of allergic reaction such as rash or itching
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is acylcar tablet used for?

This medicine contains levo-carnitine, which is used to treat carnitine deficiency. It helps the body produce energy and remove toxic substances. It is taken orally, usually 500 mg two to three times daily, as prescribed by a doctor.

  • Generic Name: Levo-carnitine
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acylcar tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लेवो-कार्निटाइन नामक सक्रिय तत्व से बनी है और मुख्य रूप से कार्निटाइन की कमी के इलाज के लिए इस्तेमाल की जाती है। कार्निटाइन शरीर में ऊर्जा बनाने और वसा को तोड़ने में मदद करता है। यह दवा उन लोगों के लिए है जिनके शरीर में पर्याप्त कार्निटाइन नहीं बनता या जो किडनी की बीमारी, दौरे की दवाओं या अन्य कारणों से कार्निटाइन खो देते हैं। यह दवा मांसपेशियों की कमजोरी, थकान और दिल की समस्याओं में सुधार कर सकती है। इसे डॉक्टर के बताए अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में परेशानी, दस्त और शरीर से मछली जैसी गंध आना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको दौरे पड़ें, सांस लेने में तकलीफ हो, चेहरे या गले में सूजन आए, या त्वचा पर चकत्ते पड़ें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से दवा की मात्रा न बदलें और न ही बंद करें। इसे पानी के साथ निगलें। अगर पेट में परेशानी हो तो इसे भोजन के साथ लें। अगर आपको किडनी, लीवर या मिर्गी की बीमारी है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। दवा को कमरे के तापमान पर सूखी जगह पर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 acylcar tablet Uses & Benefits

[{"condition":"Primary carnitine deficiency","description":"This medicine is used to treat primary carnitine deficiency, a rare genetic disorder in which the body cannot transport carnitine into cells, leading to impaired fat metabolism and energy production.","evidence":"Well-established"},{"condition":"Secondary carnitine deficiency","description":"It is used to treat secondary carnitine deficiency that may result from certain medical conditions such as chronic kidney disease, valproic acid therapy, or other metabolic disorders.","evidence":"Well-established"},{"condition":"Valproate-induced carnitine deficiency","description":"This medicine may be prescribed to prevent or treat carnitine deficiency caused by long-term use of valproic acid, an anti-seizure medication.","evidence":"Moderate"},{"condition":"Carnitine deficiency in dialysis patients","description":"Patients on chronic hemodialysis often lose carnitine and may benefit from supplementation with this medicine under medical supervision.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Fatigue in chronic illness","description":"Sometimes prescribed off-label to improve fatigue in conditions such as chronic fatigue syndrome or fibromyalgia, though evidence is limited.","evidence":"Limited"},{"condition":"Male infertility","description":"Levo-carnitine has been studied off-label to improve sperm motility and quality in some men with infertility.","evidence":"Limited"},{"condition":"Hyperthyroidism","description":"Some research suggests levo-carnitine may help manage symptoms of hyperthyroidism, but this is not an approved use.","evidence":"Limited"}]

Primary treatment for: Primary carnitine deficiency

Also treats: Secondary carnitine deficiency, Valproate-induced carnitine deficiency, Carnitine deficiency in dialysis patients

📋 Drug Information

Generic Name(s)Levo-carnitine
Brand NameAcylcar Tablet
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassVITAMINS MINERALS NUTRIENTS
Action ClassAmino acids
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist or worsen.
6
Report any unusual muscle weakness or seizures immediately.
7
Keep regular follow-up appointments for monitoring.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Muscle weakness
This medicine is commonly prescribed for carnitine deficiency causing muscle weakness.
Likely Use
✅
Fatigue
This medicine may help if fatigue is due to carnitine deficiency.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLevo-carnitine is absorbed from the gastrointestinal tract after oral administration. Absorption may be variable and can be influenced by food intake. The bioavailability of oral levo-carnitine is approximately 15% to 20% when taken on an empty stomach, but it can be higher when taken with food.
DistributionLevo-carnitine is widely distributed in the body, with highest concentrations in skeletal muscle, heart muscle, liver, and kidney. It crosses the blood-brain barrier to some extent and is also present in breast milk.
Protein BindingLevo-carnitine does not bind significantly to plasma proteins.
MetabolismLevo-carnitine is not extensively metabolized in the body. It is primarily excreted unchanged in the urine, although a small amount may be converted to trimethylamine and other metabolites by gut bacteria.
Half-LifeThe elimination half-life of levo-carnitine is approximately 3 to 4 hours in healthy individuals with normal kidney function.
ExcretionLevo-carnitine is primarily excreted unchanged in the urine. Renal clearance is an important route of elimination, and patients with kidney impairment may have reduced clearance, leading to accumulation.
BioavailabilityThe oral bioavailability of levo-carnitine is approximately 15% to 20% when taken on an empty stomach. It may be higher when taken with food.
Onset of ActionThe onset of action varies depending on the indication and individual patient factors. Improvement in symptoms of carnitine deficiency may be noticed within days to weeks of starting therapy.
Peak Plasma TimePeak plasma concentrations of levo-carnitine are typically reached within 3 to 4 hours after oral administration.
Duration of ActionThe duration of action depends on the dosing schedule and the patient's condition. With regular dosing, carnitine levels are maintained throughout the day.

How It Works

Levo-carnitine is essential for the transport of long-chain fatty acids into the mitochondria, where they are oxidized to produce energy. It also helps remove toxic acyl groups from the mitochondria, preventing their accumulation. By facilitating fatty acid oxidation, this medicine supports normal energy metabolism, especially in tissues that rely heavily on fat as fuel, such as the heart and skeletal muscles. In carnitine deficiency, supplementation restores these vital functions.

Mechanism Steps

1
Carnitine uptake into cells: Levo-carnitine is taken up into cells by specific transporters, where it becomes available for fatty acid metabolism.
2
Formation of acylcarnitine: Inside the mitochondria, carnitine combines with long-chain fatty acids to form acylcarnitine, a process catalyzed by carnitine palmitoyltransferase I.
3
Transport into mitochondria: Acylcarnitine is transported across the inner mitochondrial membrane by carnitine-acylcarnitine translocase.
4
Release of fatty acids: Once inside, acylcarnitine is converted back to carnitine and fatty acyl-CoA by carnitine palmitoyltransferase II.
5
Energy production: Fatty acyl-CoA enters beta-oxidation to produce acetyl-CoA, which enters the Krebs cycle to generate ATP, the energy currency of the cell.

💡 How to Take acylcar tablet

Strength: Levo-carnitine 500 mg immediate-release tablet

1Swallow the tablet whole with a full glass of water.
2Take with or without food, but with food if it upsets your stomach.
3Take at the same times each day to maintain consistent levels.
4Do not crush, chew, or break the tablet unless instructed by your doctor.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 500 mg to 1000 mg taken two to three times daily, depending on the indication and the patient's carnitine levels. For primary carnitine deficiency, doses may be higher. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and may require lower doses. Dose should be individualized by a clinician based on renal function.
Renal ImpairmentIn patients with kidney impairment, dose reduction may be necessary. For patients on dialysis, levo-carnitine is often given intravenously after dialysis sessions. Oral dosing should be carefully adjusted under medical supervision.
Hepatic ImpairmentNo specific dose adjustment is established for patients with liver impairment. Use with caution and under medical supervision.
Maximum Daily DoseThe maximum recommended daily dose is 3000 mg (3 grams) for adults, but this may vary based on the indication and medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May worsen condition and increase side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acylcar tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Take with food and stay hydrated. Consult doctor if severe.
Stomach discomfort (Common (5-10%))
Take with meals. If it continues, talk to your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. Consult doctor if it lasts more than a few days.
Fishy body odor (Common (5-10%))
This is harmless and may decrease over time. Discuss with your doctor if bothersome.

🚨 Serious Side Effects

Seizures (Rare (<0.1%))
Seek immediate medical attention if you experience a seizure.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face or throat, or a severe rash.
Uremic encephalopathy in kidney failure patients (Rare (<0.1%))
Seek immediate medical help if you experience confusion, weakness, or seizures.

⚠️ Rare Side Effects

Muscle weakness
Report to your doctor if you notice new or worsening muscle weakness.
Increased appetite
Monitor your weight and inform your doctor if concerned.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Valproic acid Major
Warfarin Major
Cephalosporins Moderate
Levothyroxine Moderate
Antacids Minor

🚨 Major Interactions

  • Valproic acid
  • Warfarin

⚡ Moderate Interactions

  • Cephalosporins (e.g., cefditoren)
  • Thyroid hormone (levothyroxine)

🍷 Alcohol Interaction

Alcohol can interfere with carnitine metabolism and may worsen the underlying condition. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to levo-carnitine or any component of the tablet","Severe kidney impairment without close medical supervision","Use in patients with a history of seizures should be monitored closely"]

⚠️ Warnings & Precautions

["Use with caution in patients with kidney disease, as a metabolite can accumulate and cause serious side effects.","May increase the risk of seizures in patients with a history of epilepsy.","Not recommended for use in patients with severe liver disease without medical supervision.","Do not use for weight loss or athletic performance enhancement.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not share this medicine with others."]

🤱 Lactation Safety

Levo-carnitine is present in breast milk. It is generally considered safe during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose of levo-carnitine may cause severe nausea, vomiting, diarrhea, and abdominal cramps. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Swallow the tablet whole with a full glass of water, with or without food. If it upsets your stomach, take it with meals. Inform your doctor if you have kidney disease, liver disease, epilepsy, or any other medical condition before starting this medicine. Your doctor may need to adjust your dose or monitor you more closely. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Keep this medicine out of the reach of children. Store it at room temperature, away from moisture and heat. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Never double the dose to make up for a missed one. Regular follow-up visits and blood tests may be needed to check how well the medicine is working and to monitor for side effects. Report any new or worsening symptoms to your doctor promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require lower doses. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor. This medicine may be continued if needed, but only under medical supervision.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It is generally safe to continue, but your doctor will advise.

🦷 Dental Procedures

No specific precautions are needed for dental procedures. However, inform your dentist about all medicines you take.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on muscles.
🥗
Eat a balanced diet rich in fruits, vegetables, and whole grains.
😴
Stay physically active as tolerated.
💧
Get adequate sleep to support energy levels.
🧘
Avoid alcohol and smoking.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Moderate exercise is encouraged, but avoid overexertion. Listen to your body and rest when needed. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Include lean proteins like fish, chicken, and beans.
Eat plenty of fruits and vegetables.
Choose whole grains over refined grains.
Stay well hydrated.
Limit processed foods and added sugars.

💼 Impact on Daily Work & Life

This medicine is not known to impair your ability to drive or operate machinery. However, if you experience dizziness or fatigue, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Stopping suddenly can worsen your condition. Your doctor will determine when and how to stop based on your progress.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a doctor. Regular blood tests may be needed to check carnitine levels and kidney function. In patients with kidney disease, accumulation of a metabolite can occur, so monitoring is essential.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary carnitine

Red meat and dairy are rich in carnitine, but dietary intake may not be enough for deficiency.

Evidence: Limited
Acetyl-L-carnitine supplementation

Another form of carnitine that may be used for different indications.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, adjust your dosing schedule gradually under medical advice. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with primary carnitine deficiency
He experienced severe muscle weakness and fatigue for years. After starting this medicine, his energy levels improved significantly within a few weeks. He now leads an active life and takes the medicine regularly as prescribed.
💡 Lesson: Consistent use of this medicine can dramatically improve quality of life in carnitine deficiency.
👤 A 60-year-old woman on dialysis with secondary carnitine deficiency
She suffered from muscle cramps and fatigue. Her doctor prescribed this medicine, and she noticed gradual improvement in her symptoms. She emphasizes the importance of taking it exactly as directed.
💡 Lesson: In dialysis patients, carnitine supplementation can alleviate symptoms and improve well-being.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement in symptoms may be noticed within days to weeks, depending on the individual and the severity of deficiency.

Q: Can I take it with food?

A: Yes, taking it with food can reduce stomach upset.

Q: Is it safe during pregnancy?

A: It is generally considered safe when prescribed by a doctor, but consult your doctor before use.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acylcar tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a weight loss supplement.
    Fact: This medicine is not approved for weight loss and should not be used for that purpose.
  • Myth: It can boost energy in healthy people.
    Fact: It only helps if you have a carnitine deficiency. It does not increase energy in healthy individuals.
  • Myth: It is safe to take without a prescription.
    Fact: This is a prescription medicine and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Levo-carnitine 500 mg tablet (generic)

Brand Alternatives

  • Carnisure 500 tablet

📊 Comparison with Similar Medicines

[{"medicine":"Levo-carnitine","active_ingredient":"Levo-carnitine","strength":"500 mg","form":"Tablet","route":"Oral","notes":"Immediate release"},{"medicine":"Acetyl-L-carnitine","active_ingredient":"Acetyl-L-carnitine","strength":"500 mg","form":"Tablet","route":"Oral","notes":"Different salt, used for cognitive support"}]

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