coatz-af syrup sugar free - Oxetacaine (10mg/5ml) + Simethicone (125mg/5ml) medicine

coatz-af syrup sugar free - Uses, Price, Side Effects & Substitutes

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๐Ÿญ TTK Healthcare Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is coatz-af syrup sugar free used for?

Coatz-AF Syrup (Oxetacaine + Simethicone) is used to treat GASTRO INTESTINAL. It contains Oxetacaine (10mg/5ml) + Simethicone (125mg/5ml), which Oxetacaine: Local anesthetic that blocks pain receptors in gastric mucosa; Simet. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Oxetacaine + Simethicone
  • Manufacturer: TTK Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š coatz-af syrup sugar free Uses & Benefits

Symptomatic relief of gastric pain, hyperacidity, bloating, and flatulence

Off-label uses: None established

๐Ÿ“‹ Drug Information

Generic Name(s)Oxetacaine + Simethicone
Brand NameCoatz-AF Syrup
ManufacturerTTK Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassGastrointestinal Agent
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC); protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionOxetacaine: Poorly absorbed from GI tract; Simethicone: Not absorbed
DistributionOxetacaine: Local action in GI tract; Simethicone: Not distributed systemically
Protein BindingOxetacaine: Not available; Simethicone: Not applicable
MetabolismOxetacaine: Not metabolized; Simethicone: Not metabolized
Half-LifeOxetacaine: Not available; Simethicone: Not applicable
ExcretionOxetacaine: Feces; Simethicone: Feces unchanged
BioavailabilityOxetacaine: Negligible systemic absorption; Simethicone: Not absorbed
Onset of ActionOxetacaine: Rapid (minutes); Simethicone: Rapid (minutes)
Peak Plasma TimeOxetacaine: Not applicable; Simethicone: Not applicable
Duration of ActionOxetacaine: 1-2 hours; Simethicone: 3-4 hours

How It Works

Oxetacaine: Local anesthetic that blocks pain receptors in gastric mucosa; Simethicone: Defoaming agent that reduces surface tension of gas bubbles, facilitating their expulsion

Mechanism Steps

1Oxetacaine binds to sodium channels on sensory nerve endings in gastric mucosa
2Blocks sodium influx, preventing nerve impulse generation
3Reduces pain perception in stomach

๐Ÿ’ก How to Take coatz-af syrup sugar free

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of coatz-af syrup sugar free

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Constipation

๐Ÿšจ Serious Side Effects

  • Allergic reactions (rare)

โš ๏ธ Rare Side Effects

  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

๐Ÿฝ๏ธ Food Interactions

No significant interactions

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component

๐Ÿ“Š Monitoring Parameters

Symptom relief; no specific lab monitoring required

๐Ÿคฑ Lactation Safety

Oxetacaine: Use with caution; Simethicone: Likely safe

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; gastric lavage if needed

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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