coastat 100mg injection - Tranexamic Acid (100mg) medicine

coastat 100mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Concept Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is coastat 100mg injection used for?

Armril Injection IP (Tranexamic Acid) is used to treat BLOOD RELATED. It contains Tranexamic Acid (100mg), which Competitively inhibits plasminogen activation and plasmin activity, thereby redu. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Tranexamic Acid
  • Manufacturer: Concept Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š coastat 100mg injection Uses & Benefits

Menorrhagia, epistaxis, hemoptysis, gastrointestinal bleeding, hemophilia (adjunct), dental procedures in hemophiliacs, traumatic hyphema, hereditary angioedema.

Off-label uses: Cardiac surgery, orthopedic surgery, trauma, postpartum hemorrhage.

๐Ÿ“‹ Drug Information

Generic Name(s)Tranexamic Acid
Brand NameArmril Injection IP
ManufacturerConcept Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassAntifibrinolytic
Route of AdministrationIntravenous (IV) injection or infusion.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.
DistributionDistributes widely in body tissues and fluids; crosses placenta and blood-brain barrier.
Protein BindingApproximately 3% bound to plasma proteins.
MetabolismMinimal hepatic metabolism; primarily excreted unchanged.
Half-LifeApproximately 2-11 hours (mean 3.1 hours).
ExcretionPrimarily renal (over 90% unchanged in urine).
Bioavailability100% (intravenous).
Onset of ActionRapid (within minutes).
Peak Plasma TimeImmediately after IV administration.
Duration of ActionUp to 8 hours.

How It Works

Competitively inhibits plasminogen activation and plasmin activity, thereby reducing fibrinolysis and stabilizing clots.

Mechanism Steps

1Tranexamic acid binds to lysine binding sites on plasminogen and plasmin.
2This prevents plasminogen from binding to fibrin and being activated to plasmin.
3Plasmin activity is also directly inhibited.

๐Ÿ’ก How to Take coastat 100mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of coastat 100mg injection

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache
  • Hypotension (with rapid IV injection)

๐Ÿšจ Serious Side Effects

  • Thromboembolic events (DVT, PE, stroke)
  • Acute renal cortical necrosis
  • Seizures
  • Anaphylaxis
  • Visual disturbances

โš ๏ธ Rare Side Effects

  • Color vision disturbances
  • Retinal artery occlusion
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased risk of thrombosis due to opposing mechanisms.
Heparin Major Increased risk of thrombosis.
Aspirin Moderate Additive antiplatelet effect may increase bleeding risk.
Oral Contraceptives Moderate Increased risk of thromboembolism.

๐Ÿšจ Major Interactions

  • Warfarin
  • Heparin
  • Low molecular weight heparins
  • Direct oral anticoagulants (DOACs)
  • Thrombolytics (e.g., alteplase)

โšก Moderate Interactions

  • Aspirin
  • NSAIDs
  • Clopidogrel
  • Antiplatelet agents
  • Estrogens
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • Tetracyclines
  • Penicillins

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to tranexamic acid; active intravascular clotting; history of thromboembolic disease; subarachnoid hemorrhage; severe renal impairment.

๐Ÿ“Š Monitoring Parameters

Renal function, signs of thrombosis, bleeding control.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; consider hemodialysis if severe.

โฐ Missed Dose

Not applicable for single-dose or intermittent IV use; follow prescribed schedule.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for coastat 100mg injection

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Alternative brands with exact same active ingredient (Tranexamic Acid (100mg)):

Medical Note: Always consult your doctor before switching medications.

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