clopizim 75mg tablet - Clopidogrel (75mg) medicine

clopizim 75mg tablet

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Clopidogrel (75mg)
🏭 Zim Laboratories Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

What is clopizim 75mg tablet used for?

This medicine contains Clopidogrel (75mg) and is used to treat BLOOD RELATED. Irreversibly inhibits the P2Y12 receptor on platelets, preventing ADP-mediated platelet aggregation.. Always consult your doctor before use.

  • Generic Name: Clopidogrel
  • Manufacturer: Zim Laboratories Limited
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 clopizim 75mg tablet Uses & Benefits

Prevention of atherosclerotic events (MI, stroke, vascular death) in patients with atherosclerosis; acute coronary syndrome; recent MI or stroke; peripheral arterial disease.

Off-label uses: Prevention of stent thrombosis, adjunctive therapy in PCI.

📋 Drug Information

Generic Name(s)Clopidogrel
Brand NameAclizac 75mg Tablet
ManufacturerZim Laboratories Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassP2Y12 inhibitors (ADP receptor)
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; absorption is at least 50%.
DistributionWidely distributed; extensively bound to plasma proteins.
Protein Binding94-98%
MetabolismHepatic; prodrug activated by CYP2C19 and other CYP450 enzymes.
Half-LifeApproximately 6 hours (active metabolite); parent drug ~8 hours.
Excretion50% renal, 46% fecal.
BioavailabilityAt least 50%.
Onset of Action2 hours after loading dose.
Peak Plasma Time0.75-1 hour (parent drug); active metabolite ~1 hour.
Duration of Action5-10 days (platelet inhibition persists for life of platelet).

How It Works

Irreversibly inhibits the P2Y12 receptor on platelets, preventing ADP-mediated platelet aggregation.

Mechanism Steps

1Clopidogrel is a prodrug absorbed in the intestine.
2Converted to active metabolite via CYP2C19 and other CYP450 enzymes in the liver.
3Active metabolite irreversibly binds to P2Y12 receptor on platelets.
4Blocks ADP binding and subsequent activation of GPIIb/IIIa receptor.
5Inhibits platelet aggregation for the lifespan of the platelet (7-10 days).

💡 How to Take clopizim 75mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of clopizim 75mg tablet

✅ Common Side Effects

Bleeding
Bruising
Diarrhea
Abdominal pain
Dyspepsia

🚨 Serious Side Effects

Severe bleeding
Thrombotic thrombocytopenic purpura
Hemorrhagic stroke

⚠️ Rare Side Effects

Allergic reactions
Hepatotoxicity
Neutropenia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased bleeding risk
NSAIDs Major Increased bleeding risk
Omeprazole Moderate Reduced clopidogrel efficacy
Aspirin Major Increased bleeding risk

🚨 Major Interactions

  • Warfarin
  • NSAIDs
  • Rivaroxaban
  • Apixaban
  • Dabigatran
  • Heparin
  • Aspirin

⚡ Moderate Interactions

  • Omeprazole
  • Esomeprazole
  • Fluoxetine
  • Fluconazole
  • Ketoconazole
  • Cimetidine

🍷 Alcohol Interaction

May increase bleeding risk; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Active bleeding, severe liver impairment, hypersensitivity to clopidogrel.

🤱 Lactation Safety

Not recommended; excreted in breast milk.

💊 Overdose Management

No specific antidote; platelet transfusion may be considered.

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.

🔄 Substitutes for clopizim 75mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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