Aclotil 75mg Tablet (Clopidogrel): Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding that doesn't stop
If experiencing severe symptoms, call emergency services immediately.
What is anticlot 75 tablet used for?
This medicine is an antiplatelet tablet containing Clopidogrel 75 mg. It is used to prevent heart attacks and strokes in people with cardiovascular disease. It works by stopping platelets from sticking together. It is usually taken once daily, with or without food. Do not stop taking it without your doctor's advice.
- Generic Name: Clopidogrel (75mg)
- Manufacturer: Scott Edil Pharmacia Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anticlot 75 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोपिडोग्रेल 75 मिलीग्राम की एक एंटीप्लेटलेट गोली है। यह दिल के दौरे, स्ट्रोक और अन्य हृदय संबंधी समस्याओं को रोकने के लिए दी जाती है। यह खून में प्लेटलेट्स को चिपकने से रोकती है, जिससे खून के थक्के नहीं बनते। यह आमतौर पर दिन में एक बार ली जाती है, खाने के साथ या बिना। इसे डॉक्टर की सलाह के बिना बंद न करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में आसानी से चोट लगना, नाक से खून आना, और छोटी चोट से खून बहना शामिल है। कुछ लोगों को पेट में परेशानी, दस्त, या दाने हो सकते हैं। गंभीर दुष्प्रभावों में गंभीर रक्तस्राव, जैसे पेट या दिमाग में रक्तस्राव, और एक दुर्लभ रक्त विकार थ्रोम्बोटिक थ्रोम्बोसाइटोपेनिक पुरपुरा (टीटीपी) शामिल हैं। अगर आपको असामान्य रक्तस्राव, काला या खूनी मल, खून की उल्टी, या स्ट्रोक के लक्षण दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। डॉक्टर की सलाह के बिना खुराक न बदलें और न ही दवा बंद करें। किसी भी सर्जरी या दंत चिकित्सा से पहले अपने डॉक्टर को इस दवा के बारे में बताएं। चोट लगने से बचें। नरम टूथब्रश और इलेक्ट्रिक रेजर का इस्तेमाल करें। शराब से बचें, क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। अगर आपको खुराक लेना भूल जाए, तो याद आते ही ले लें, लेकिन अगर अगली खुराक का समय हो गया है, तो छोड़ी हुई खुराक को छोड़ दें और सामान्य शेड्यूल जारी रखें। दोहरी खुराक न लें।
💊 anticlot 75 tablet Uses & Benefits
[{"condition":"Acute coronary syndrome (heart attack or unstable angina)","description":"This medicine is used in combination with aspirin to reduce the risk of recurrent heart attacks and death in patients who have had a heart attack or unstable angina.","evidence":"Well-established"},{"condition":"Recent myocardial infarction (heart attack)","description":"Long-term use after a heart attack helps prevent future cardiovascular events.","evidence":"Well-established"},{"condition":"Recent ischemic stroke or transient ischemic attack (TIA)","description":"This medicine reduces the risk of recurrent stroke or TIA in patients who have already had one.","evidence":"Well-established"},{"condition":"Peripheral arterial disease","description":"It helps prevent cardiovascular events in patients with narrowed peripheral arteries.","evidence":"Well-established"},{"condition":"Prevention of stent thrombosis after coronary stent placement","description":"Used with aspirin to prevent blood clots from forming inside a newly placed coronary stent.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of cardiovascular events in patients with diabetes","description":"Sometimes prescribed off-label to reduce cardiovascular risk in diabetic patients with additional risk factors.","evidence":"Limited"},{"condition":"Prevention of thromboembolism in atrial fibrillation","description":"Occasionally used off-label when warfarin is not suitable, but not a standard first-line treatment.","evidence":"Limited"}]
Primary treatment for: Cardiovascular diseases (e.g., acute coronary syndrome, recent myocardial infarction, recent ischemic stroke, peripheral arterial disease)
Also treats: Coronary artery disease, Cerebrovascular disease, Peripheral artery disease
📋 Drug Information
| Generic Name(s) | Clopidogrel (75mg) |
| Brand Name | anticlot 75 tablet |
| Manufacturer | Scott Edil Pharmacia Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | P2Y12 inhibitors (ADP receptor) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from moisture and heat. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. Guidelines from organizations such as the American College of Cardiology and the European Society of Cardiology recommend clopidogrel for secondary prevention of cardiovascular events in specific patient populations. |
| ICMR Guideline | Not established from the available information. Consult local guidelines for specific recommendations. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by irreversibly blocking a specific receptor on the surface of platelets called the P2Y12 receptor. Platelets are tiny blood cells that help form clots. When this receptor is blocked, adenosine diphosphate (ADP) cannot bind to it, which prevents the activation of a protein complex called glycoprotein IIb/IIIa. This ultimately stops platelets from clumping together and forming a clot. Because the blockade is irreversible, the effect lasts for the lifespan of the platelet, which is about 7 to 10 days. This is why bleeding risk persists for several days after stopping the medicine.
Mechanism Steps
💡 How to Take anticlot 75 tablet
Strength: Tablet, 75 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 75 mg taken orally once daily, with or without food. In acute coronary syndrome, a loading dose of 300 mg or 600 mg may be given as a single dose, followed by 75 mg once daily. The dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and concomitant medications. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but they may be more susceptible to bleeding. Use with caution and monitor closely. |
| Renal Impairment | No dose adjustment is necessary for patients with renal impairment. However, use with caution in severe renal impairment due to increased bleeding risk. |
| Hepatic Impairment | No dose adjustment is necessary for patients with mild to moderate hepatic impairment. However, this medicine is contraindicated in patients with severe hepatic impairment. |
| Maximum Daily Dose | 75 mg per day for maintenance therapy. Loading doses of up to 600 mg may be used in acute settings under medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anticlot 75 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Omeprazole | Major | |
| SSRIs | Major | |
| Aspirin | Major | |
| Fluconazole | Moderate | |
| Ketoconazole | Moderate | |
| Erythromycin | Moderate | |
| Carbamazepine | Moderate | |
| Rifampicin | Moderate |
🚨 Major Interactions
- Warfarin
- NSAIDs (e.g., ibuprofen, naproxen)
- Omeprazole and esomeprazole
- SSRIs (e.g., fluoxetine, sertraline)
- Other antiplatelet drugs (e.g., aspirin, ticagrelor, prasugrel)
⚡ Moderate Interactions
- Fluconazole
- Ketoconazole
- Erythromycin
- Carbamazepine
- Rifampicin
🍷 Alcohol Interaction
Alcohol may increase the risk of gastrointestinal bleeding when taken with this medicine. It is advisable to avoid alcohol or limit its intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clopidogrel or any component of the formulation","Active pathological bleeding such as peptic ulcer or intracranial hemorrhage","Severe hepatic impairment","Known bleeding disorders (e.g., hemophilia)","Concurrent use with strong CYP2C19 inhibitors (e.g., omeprazole, esomeprazole) may reduce efficacy"]
⚠️ Warnings & Precautions
["This medicine increases the risk of bleeding. Use with caution in patients at risk of bleeding.","Do not stop taking this medicine without consulting your doctor, as it may increase the risk of cardiovascular events.","Inform your doctor if you are scheduled for surgery or dental procedures. You may need to stop the medicine temporarily.","Patients with genetic variations in CYP2C19 may have reduced response to this medicine. Consider alternative therapy if poor metabolism is suspected.","Use with caution in elderly patients, who may be more prone to bleeding.","Avoid concurrent use with NSAIDs or other drugs that increase bleeding risk unless absolutely necessary.","Monitor for signs of thrombotic thrombocytopenic purpura (TTP), a rare but serious condition."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose with this medicine may lead to prolonged bleeding time and bleeding complications. There is no specific antidote. In case of overdose, seek immediate medical attention. Treatment is supportive and may include platelet transfusion if severe bleeding occurs. Hemodialysis is not effective in removing the drug from the blood.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Inform all your healthcare providers, including dentists and surgeons, that you are taking this medicine before any procedure. Avoid activities that increase the risk of injury or bleeding. Use a soft toothbrush and an electric razor to reduce bleeding risk. Avoid alcohol, as it can increase the risk of stomach bleeding. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to bleeding while taking this medicine. Use with caution and monitor for signs of bleeding. No specific dose adjustment is required, but regular follow-up is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
After surgery, your doctor will decide when it is safe to restart this medicine. It is often stopped 5-7 days before surgery to reduce bleeding risk. Do not restart without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. You may need to stop it temporarily to reduce bleeding risk. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can exercise, but avoid activities that carry a high risk of falls or injury, such as contact sports or heavy lifting. If you experience any bleeding or unusual bruising, consult your doctor before continuing your exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or any bleeding, avoid these activities until you feel better. Inform your employer if your job involves a high risk of injury.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor may advise stopping it before certain surgeries or if you develop serious bleeding. Always follow your doctor's instructions.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for preventing cardiovascular events. However, it increases the risk of bleeding, which may require monitoring. Regular follow-up with your doctor is important to assess kidney and liver function, and to watch for any signs of bleeding. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another antiplatelet drug that may be used alone or with clopidogrel.
Evidence: Well-establishedAlternative P2Y12 inhibitors that may be used in certain patients.
Evidence: Well-establishedDiet, exercise, and smoking cessation can complement medicine.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are due for surgery or a procedure, inform your doctor about your vaccination status. There are no specific contraindications for vaccinations while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your dose at the same local time as usual, but consult your doctor if you are unsure. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 2 hours after a dose, but its full antiplatelet effect may take several days of regular use. In emergency situations, a loading dose may be given to achieve a faster effect.
A: No, you should never stop taking this medicine without consulting your doctor. Stopping suddenly can increase your risk of heart attack or stroke.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Alcohol may increase the risk of gastrointestinal bleeding. It is best to avoid alcohol or limit its intake while taking this medicine.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor to weigh the benefits and risks.
🤔 Common Patient Concerns
🔄 Substitutes for anticlot 75 tablet
View AllAlternative brands with exact same active ingredient:
-
glory 75mg tabletEthix Healthcare ₹5.00 37.3% CHEAPER
-
clopiril 75 tabletZeelab Pharmacy Pvt Ltd ₹15.00 88.2% COSTLIER
-
clopigard 75mg tabletCipla Ltd ₹15.09 89.3% COSTLIER
-
davaindia clopidogrel 75mg tabletDavaindia Generic Pharmacy ₹18.00 125.8% COSTLIER
-
clopizim 75mg tabletZim Laboratories Limited ₹20.16 152.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a blood thinner.
Fact: This medicine is an antiplatelet drug, not an anticoagulant. It works differently from blood thinners like warfarin. - Myth: I can stop taking this medicine once I feel better.
Fact: You should never stop taking this medicine without consulting your doctor, as it can increase your risk of heart attack or stroke. - Myth: This medicine can be taken for any type of pain.
Fact: This medicine is not a painkiller. It is used specifically for preventing blood clots in cardiovascular conditions.
🔄 Alternative Options
Generic Alternatives
- Clopidogrel 75 mg tablet
Brand Alternatives
- Plavix
- Clopilet
- Deplatt