Clomeva Nc 50mg Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain over a few days
- Difficulty breathing or shortness of breath
- Blurred vision, double vision, or seeing spots
- Severe nausea and vomiting
- Yellowing of the skin or eyes
- Dark urine or pale stools
- Swelling of the face, lips, or throat
- Chest pain or palpitations
- Sudden severe headache
If experiencing severe symptoms, call emergency services immediately.
What is clomeva nc 50mg tablet used for?
This medicine is a combination of clomiphene 50 mg and coenzyme Q10 75 mg used to induce ovulation in women with anovulatory infertility. It works by stimulating the release of hormones that promote egg maturation and release. It is taken by mouth for 5 days at the start of the menstrual cycle, under medical supervision.
- Generic Name: Clomiphene + Coenzyme Q10
- Manufacturer: VIVO Life Science
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clomeva nc 50mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोमिफीन 50 मिलीग्राम और कोएंजाइम क्यू10 75 मिलीग्राम का संयोजन है। इसका उपयोग उन महिलाओं में ओव्यूलेशन (अंडोत्सर्जन) को प्रेरित करने के लिए किया जाता है जो नियमित रूप से ओव्यूलेट नहीं करती हैं। यह दवा मस्तिष्क में एस्ट्रोजन रिसेप्टर्स को अवरुद्ध करके काम करती है, जिससे फॉलिकल-स्टिमुलेटिंग हार्मोन और ल्यूटिनाइजिंग हार्मोन का स्तर बढ़ता है और अंडे की परिपक्वता और रिहाई को बढ़ावा मिलता है। कोएंजाइम क्यू10 एक एंटीऑक्सिडेंट है जो अंडे की गुणवत्ता में सुधार करने में मदद कर सकता है। यह दवा मुँह से ली जाती है और इसे किसी फर्टिलिटी विशेषज्ञ की देखरेख में ही लेना चाहिए।
साइड इफेक्ट्स: इस दवा के अधिकांश दुष्प्रभाव हल्के और अस्थायी होते हैं। आम दुष्प्रभावों में गर्म लहरें, पेट में सूजन या असुविधा, मतली, सिरदर्द और स्तन में कोमलता शामिल हैं। कुछ महिलाओं को मूड स्विंग, चक्कर आना या दृष्टि में बदलाव जैसे धुंधला दिखना या दोहरा दिखना भी हो सकता है। कोएंजाइम क्यू10 आमतौर पर अच्छी तरह से सहन किया जाता है, लेकिन कभी-कभी हल्का पेट खराब, भूख न लगना या त्वचा पर दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम हो सकता है, जिसमें गंभीर पेट दर्द, तेजी से वजन बढ़ना और सांस लेने में कठिनाई हो सकती है। यदि आपको दृष्टि में कोई बदलाव दिखे, तो तुरंत दवा बंद करें और डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को अपने फर्टिलिटी विशेषज्ञ के निर्देशानुसार ही लें। बिना सलाह के खुराक न बढ़ाएं या घटाएं। दवा शुरू करने से पहले गर्भावस्था और अंडाशय की पुटिकाओं को बाहर करने के लिए पूरी जांच कराएं। उपचार के दौरान बैरियर गर्भनिरोधक का उपयोग करें जब तक कि आपके डॉक्टर अन्यथा सलाह न दें। यदि आपको धुंधला दिखना या चक्कर आना हो, तो वाहन चलाने या भारी मशीनरी चलाने से बचें। यदि आपको यकृत रोग, थायरॉइड समस्या या रक्त के थक्के का इतिहास है, तो अपने डॉक्टर को बताएं। इस दवा को लेते समय स्तनपान न कराएं। अल्ट्रासाउंड और हार्मोन निगरानी के लिए सभी फॉलो-अप अपॉइंटमेंट रखें।
💊 clomeva nc 50mg tablet Uses & Benefits
- [{"condition":"Ovulation induction in anovulatory infertility","description":"This medicine is used to stimulate ovulation in women who do not ovulate regularly, such as those with polycystic ovary syndrome.
- It helps restore regular menstrual cycles and improves the chance of conception.","evidence":"Well-established"},{"condition":"Unexplained infertility","description":"Sometimes prescribed to increase the number of eggs released per cycle, thereby improving the chances of pregnancy in couples with unexplained infertility.","evidence":"Moderate"},{"condition":"Luteal phase defect","description":"May be used to improve ovulation and support the luteal phase in women with short menstrual cycles or low progesterone levels.","evidence":"Limited"}]
Off-label uses: [{"condition":"Male hypogonadism","description":"Clomiphene has been used off-label in men to raise testosterone levels by stimulating the pituitary gland, but this combination product is not approved for male use.","evidence":"Limited"},{"condition":"Gynecomastia","description":"Rarely used off-label in men to reduce breast enlargement, but this is not a standard indication for this combination.","evidence":"Limited"}]
Primary treatment for: Anovulatory infertility
Also treats: Polycystic ovary syndrome, Unexplained infertility, Luteal phase defect
📋 Drug Information
| Generic Name(s) | Clomiphene + Coenzyme Q10 |
| Brand Name | CCQ 100 Tablet |
| Manufacturer | VIVO Life Science |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Ovulation stimulant / Antioxidant |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablet in its original container, tightly closed. Protect from light, moisture, and heat. Do not store in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture. Do not use after the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Clomiphene is a selective estrogen receptor modulator that binds to estrogen receptors in the hypothalamus and pituitary gland. By blocking estrogen feedback, it increases the secretion of gonadotropin-releasing hormone, which in turn raises follicle-stimulating hormone and luteinizing hormone levels. These hormones stimulate the ovaries to produce and release mature eggs. Coenzyme Q10 is a fat-soluble antioxidant that participates in mitochondrial electron transport and protects cells from oxidative damage. In the context of fertility, it may improve oocyte quality and ovarian response by reducing oxidative stress.
Mechanism Steps
💡 How to Take clomeva nc 50mg tablet
Strength: Each tablet contains clomiphene 50 mg and coenzyme Q10 75 mg. The tablet is for oral use only.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken by mouth once daily for 5 days, starting on day 2, 3, 4, or 5 of your menstrual cycle, or as directed by your fertility specialist. The dose and duration may vary depending on your individual response and the specific protocol used by your doctor. Do not self-adjust the dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not intended for use in children. Consult a pediatrician for any concerns. |
| Elderly Dosage | This medicine is not intended for use in postmenopausal women. Safety and efficacy in elderly patients have not been established. Consult your doctor for individualized advice. |
| Renal Impairment | No specific dose adjustment is provided for renal impairment in the available information. Use with caution in patients with kidney disease. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with liver disease. If you have mild hepatic impairment, your doctor may adjust the dose or recommend alternative treatment. Regular liver function monitoring is advised. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (clomiphene 50 mg + coenzyme Q10 75 mg). Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clomeva nc 50mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Gonadotropins | Major | |
| Tamoxifen | Major | |
| Fluoxetine | Moderate | |
| Paroxetine | Moderate | |
| Thyroid hormones | Moderate | |
| Antidiabetic drugs | Moderate | |
| Antacids | Minor | |
| Blood pressure medications | Minor | |
| Grapefruit juice | Moderate |
🚨 Major Interactions
- Other fertility medications (e.g., gonadotropins)
- Warfarin
- Tamoxifen
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- Thyroid hormones
- Antidiabetic drugs
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both clomiphene and alcohol are processed by the liver, and combining them can increase the risk of liver damage. Alcohol may also worsen side effects such as dizziness, drowsiness, and mood changes. If you are trying to conceive, it is best to avoid alcohol altogether.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to clomiphene, coenzyme Q10, or any component of the formulation","Pregnancy or suspected pregnancy","Liver disease or history of liver dysfunction","Unexplained abnormal vaginal bleeding","Ovarian cysts not due to polycystic ovary syndrome","Primary ovarian failure","Breastfeeding"]
⚠️ Warnings & Precautions
["This medicine should only be used under the supervision of a fertility specialist.","Visual disturbances may occur; stop the medicine and consult your doctor immediately if they develop.","Ovarian hyperstimulation syndrome is a rare but serious risk; report severe abdominal pain, bloating, or rapid weight gain.","Multiple pregnancies (twins or more) are more common with ovulation induction.","Use barrier contraception during treatment unless otherwise advised by your doctor.","Avoid alcohol while taking this medicine.","Inform your doctor if you have a history of blood clots, thyroid disease, or diabetes.","Do not take this medicine if you are already pregnant."]
🤱 Lactation Safety
It is not known whether clomiphene or coenzyme Q10 passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding is not recommended while taking this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe nausea, vomiting, abdominal pain, hot flashes, blurred vision, and ovarian hyperstimulation. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose was recent. Monitor vital signs and fluid balance closely.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you miss multiple doses, contact your doctor for advice.
Additional Safety Advice
Take this medicine exactly as prescribed by your fertility specialist. Do not increase or decrease the dose without medical advice. You should have a thorough gynecological examination before starting this medicine to rule out pregnancy and ovarian cysts. Use a barrier method of contraception during treatment unless your doctor advises otherwise, because this medicine can harm a developing baby if you become pregnant while taking it. Avoid driving or operating heavy machinery if you experience blurred vision or dizziness. Inform your doctor if you have liver disease, thyroid problems, or a history of blood clots. Do not breastfeed while taking this medicine. Keep all follow-up appointments for ultrasound and hormone monitoring. Store the tablet in its original container away from moisture and heat. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in postmenopausal women. Safety and efficacy in elderly patients have not been established. Fertility treatment is generally not recommended for women over 45 due to reduced ovarian reserve and increased risks.
🤰 Pregnancy Planning (TTC)
This medicine is used specifically to help you conceive. However, it must not be taken if you are already pregnant. If you suspect you might be pregnant, stop the medicine and take a pregnancy test. If positive, contact your doctor immediately. If you are planning pregnancy, discuss all medications and supplements with your doctor to ensure safety.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery due to the risk of blood clots. Your doctor will advise you on when to stop and when to restart. Do not stop the medicine on your own.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There is no specific contraindication, but your dentist may take precautions if you have any bleeding disorders or are on other medications. Maintain good oral hygiene as hormonal changes can affect gum health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness, visual disturbances, or severe abdominal pain, avoid exercise and consult your doctor. High-intensity workouts may not be advisable during ovarian stimulation due to the risk of ovarian torsion. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, visual disturbances, or mood swings in some women, which could affect your ability to drive or operate machinery. If you experience these side effects, avoid driving or operating heavy machinery until you feel normal. Otherwise, most women can continue their normal work and daily activities. Plan your monitoring appointments around your work schedule.
🛑 When to Stop This Medicine
Stop taking this medicine and contact your doctor immediately if you experience visual disturbances, severe abdominal pain, rapid weight gain, difficulty breathing, or signs of an allergic reaction. Do not stop the medicine without consulting your doctor if you are in the middle of a treatment cycle, unless you have a serious side effect. If you do not conceive after the recommended number of cycles, your doctor will advise you on whether to continue or switch to another treatment.
📅 Long-Term Use Effects
Long-term use of this medicine beyond the recommended number of cycles is not advised without specialist supervision. Prolonged use may increase the risk of ovarian cysts and possibly ovarian tumors, although the evidence is not conclusive. Regular monitoring of liver function and ovarian health is recommended. If you do not conceive after 3 to 6 cycles, your doctor may consider alternative treatments. Do not continue this medicine indefinitely without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another oral ovulation induction agent that may be used as an alternative, especially in women with PCOS.
Evidence: Well-establishedInjectable hormones that directly stimulate the ovaries; used when oral agents fail.
Evidence: Well-establishedWeight loss, diet, and exercise can improve ovulation in overweight women with PCOS.
Evidence: Well-establishedSome studies suggest acupuncture may improve ovulation and fertility, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are planning to receive any vaccine, inform your doctor. It is generally safe to receive vaccines while taking this medicine, but your doctor may advise timing based on your overall health and fertility treatment plan.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a letter from your doctor explaining the medical need, especially for international travel. Store the tablets in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine at the same time each day according to your home schedule, or adjust as advised by your doctor. Keep the medicine in your carry-on luggage to avoid loss or temperature extremes. Check customs regulations for restricted medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovulation typically occurs 5 to 10 days after completing the 5-day course. Your doctor will monitor your response with ultrasound or blood tests.
A: No, this is a prescription-only medicine. It must be used under the supervision of a fertility specialist.
A: No, this medicine is contraindicated during pregnancy. If you become pregnant, stop the medicine immediately and contact your doctor.
A: Common side effects include hot flashes, abdominal bloating, nausea, headache, and breast tenderness. Most are mild and temporary.
A: It is best to avoid alcohol as it can increase the risk of liver problems and worsen side effects like dizziness.
A: Yes, ovulation induction medicines like this can increase the chance of multiple pregnancies, including twins.
🤔 Common Patient Concerns
🔄 Substitutes for clomeva nc 50mg tablet
View AllAlternative brands with exact same active ingredient:
-
e ova plus 50mg tabletKoye Pharmaceuticals Pvt ltd ₹327.19 18% CHEAPER
-
Smartova 50 CombipackPharmanova India Drugs Pvt Ltd ₹399.00 SAME PRICE
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: This medicine improves ovulation and increases the chance of pregnancy, but it does not guarantee success. Many factors affect fertility. - Myth: This medicine is safe to take without monitoring.
Fact: This medicine requires regular monitoring by a fertility specialist to ensure safety and effectiveness. - Myth: Coenzyme Q10 in this medicine is only for energy.
Fact: Coenzyme Q10 is an antioxidant that may help improve egg quality and ovarian response in fertility treatment.
🔄 Alternative Options
Generic Alternatives
- Clomiphene 50 mg tablet
- Coenzyme Q10 75 mg capsule