Cibis Tablet: Complete Guide to Uses, Side Effects, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing.
- Mental confusion, hallucinations, or unusual behavior.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain.
- Unusual bleeding or bruising, fever, or sore throat.
- Inability to urinate or severe constipation.
- Severe drowsiness, slow breathing, or loss of consciousness.
- Chest pain, palpitations, or irregular heartbeat.
If experiencing severe symptoms, call emergency services immediately.
What is clibtab d 2.5mg/5mg/10mg tablet used for?
This medicine is a combination of clidinium (an antispasmodic) and chlordiazepoxide (an anxiolytic) used to treat abdominal cramps, spasms, and discomfort in conditions like irritable bowel syndrome and peptic ulcer disease. It works by relaxing gut muscles and reducing anxiety. It is for short-term use only and should be taken exactly as prescribed.
- Generic Name: Clidinium + Chlordiazepoxide
- Manufacturer: Green Bract Lifesciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 clibtab d 2.5mg/5mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लिडिनियम और क्लोरडायजेपॉक्साइड का संयोजन है, जिसका उपयोग पेट की ऐंठन, दर्द, और असुविधा के इलाज के लिए किया जाता है, विशेष रूप से इरिटेबल बाउल सिंड्रोम (IBS) और पेप्टिक अल्सर में। यह आंतों की मांसपेशियों को आराम देकर और चिंता को कम करके काम करती है। यह दवा केवल अल्पकालिक उपयोग के लिए है और इसे डॉक्टर के निर्देशानुसार ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, नींद आना, चक्कर आना, धुंधली दृष्टि, कब्ज, और पेशाब में रुकावट शामिल हैं। गंभीर दुष्प्रभावों में भ्रम, मतिभ्रम, पीलिया, और रक्त विकार हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक कि आपको इस दवा का असर पता न चल जाए। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। दवा को अचानक बंद न करें।
💊 clibtab d 2.5mg/5mg/10mg tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS)","description":"Helps relieve abdominal pain, cramping, bloating, and altered bowel habits associated with IBS.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Used as an adjunct to reduce gastric acid secretion and relieve associated pain and spasm.","evidence":"Established"},{"condition":"Gastrointestinal motility disorders","description":"Reduces smooth muscle spasms in conditions like spastic colon and functional dyspepsia.","evidence":"Established"},{"condition":"Anxiety-related gastrointestinal symptoms","description":"The anxiolytic component helps reduce stress-induced gut symptoms.","evidence":"Limited"}]
Off-label uses: [{"condition":"Preoperative sedation","description":"Occasionally used for its sedative and muscle-relaxant properties before minor procedures.","evidence":"Limited"},{"condition":"Tension headaches","description":"Sometimes prescribed off-label for muscle tension headaches.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome
Also treats: Peptic ulcer disease, Gastrointestinal motility disorders, Anxiety-related gastrointestinal symptoms
📋 Drug Information
| Generic Name(s) | Clidinium + Chlordiazepoxide |
| Brand Name | Avidip |
| Manufacturer | Green Bract Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Anticholinergic + Benzodiazepine |
| Route of Administration | Oral |
| Storage | Store at room temperature (15–30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Clidinium is a quaternary ammonium antimuscarinic agent that competitively inhibits acetylcholine at muscarinic receptors on gastrointestinal smooth muscle, reducing spasms, motility, and secretions. Chlordiazepoxide is a long-acting benzodiazepine that binds to the benzodiazepine site on GABA-A receptors, enhancing the inhibitory effect of GABA, which leads to anxiolytic, sedative, and muscle-relaxant effects. Together, they reduce both the physical and psychological components of gastrointestinal distress.
Mechanism Steps
💡 How to Take clibtab d 2.5mg/5mg/10mg tablet
Strength: Each immediate-release tablet contains Clidinium 2.5 mg and Chlordiazepoxide 5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken 3 to 4 times daily, before meals and at bedtime. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, and hepatic and renal function. Do not self-adjust the dose. This medicine is intended for short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of chlordiazepoxide and clidinium. Start with a lower dose and titrate slowly. Use with caution due to increased risk of confusion, falls, urinary retention, and constipation. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary based on clinical response and renal function. Consult a clinician. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Chlordiazepoxide undergoes hepatic metabolism; reduce dose and monitor liver function. Consult a clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 4 tablets (10 mg chlordiazepoxide and 5 mg clidinium per day). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of clibtab d 2.5mg/5mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Opioids | Major | |
| Alcohol | Major | |
| MAO inhibitors | Major | |
| Antihistamines | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Cimetidine | Moderate | |
| Oral contraceptives | Moderate | |
| Levodopa | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CNS depressants (e.g., opioids, alcohol, barbiturates)
- MAO inhibitors
- Anticholinergic drugs (e.g., antihistamines, tricyclic antidepressants)
⚡ Moderate Interactions
- Cimetidine
- Oral contraceptives
- Levodopa
🍷 Alcohol Interaction
Alcohol significantly increases the sedative and CNS depressant effects of chlordiazepoxide, leading to excessive drowsiness, impaired coordination, respiratory depression, and increased risk of accidents. Avoid alcohol completely while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to clidinium, chlordiazepoxide, or any component of the formulation","Glaucoma (narrow-angle)","Myasthenia gravis","Severe liver disease","Severe respiratory insufficiency","Acute narrow-angle glaucoma","Benign prostatic hyperplasia with urinary retention","Pregnancy (especially first trimester)","Breastfeeding"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","May cause dependence and withdrawal symptoms with prolonged use; taper gradually.","Use with caution in elderly patients due to increased risk of confusion, falls, and anticholinergic effects.","Use with caution in patients with hepatic or renal impairment.","May exacerbate glaucoma, urinary retention, and constipation.","Do not use in children unless prescribed by a pediatrician.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Chlordiazepoxide is excreted in breast milk and may cause sedation in the infant. Clidinium may also pass into breast milk. Consult your doctor before breastfeeding; alternative feeding may be advised.
💊 Overdose Management
Overdose may cause severe drowsiness, confusion, coma, respiratory depression, and anticholinergic symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. Flumazenil may be used for benzodiazepine toxicity but is contraindicated in mixed overdose with tricyclic antidepressants. Physostigmine may be considered for severe anticholinergic toxicity. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine, as it can increase drowsiness and impair judgment. Inform your doctor if you have glaucoma, enlarged prostate, difficulty urinating, liver disease, kidney disease, or a history of substance abuse. Do not stop this medicine suddenly after prolonged use, as it can cause withdrawal symptoms. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of chlordiazepoxide and clidinium. They are at higher risk of confusion, falls, urinary retention, constipation, and cognitive impairment. Use with caution, start with a lower dose, and monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the first trimester, due to potential risk of fetal harm. If you are planning pregnancy, consult your doctor to discuss alternative treatments. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery as advised by your doctor.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental caries and oral infections. Inform your dentist that you are taking this medicine. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light to moderate exercise like walking or yoga is generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. Avoid these activities until you know how the medicine affects you. Inform your employer if your job involves such tasks.
🛑 When to Stop This Medicine
Do not stop this medicine abruptly, especially after prolonged use, as it can cause withdrawal symptoms such as anxiety, insomnia, and tremors. Consult your doctor before stopping; they may recommend a gradual taper. If you experience serious side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Prolonged use of this medicine can lead to physical dependence, tolerance, and withdrawal symptoms upon abrupt discontinuation. Long-term anticholinergic effects may include cognitive impairment, especially in the elderly. Regular monitoring of liver function, mental status, and signs of dependence is recommended. This medicine is not intended for long-term use; alternative treatments should be considered for chronic conditions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A low-FODMAP diet or fiber supplementation can help manage IBS symptoms.
Evidence: Well-establishedCognitive behavioral therapy, meditation, and yoga can reduce stress-related gut symptoms.
Evidence: Well-establishedCertain probiotic strains may improve gut health and reduce IBS symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. No known interactions with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations regarding controlled substances, as chlordiazepoxide may be regulated.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Antispasmodic effects may begin within 1–2 hours, while anxiolytic effects may take several days for full benefit.
A: Inform your doctor about all medications you are taking, as this medicine can interact with many drugs, including CNS depressants, MAO inhibitors, and anticholinergics.
A: Yes, chlordiazepoxide can cause dependence with prolonged use. It should be used short-term and tapered gradually under medical supervision.
A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for clibtab d 2.5mg/5mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
libopil 5 mg/2.5 mg tabletPsychotropics India Ltd ₹5.33 81.6% CHEAPER
-
cromide forte 2.5 mg/5 mg/10 mg tabletLeeford Healthcare Ltd ₹7.50 74.1% CHEAPER
-
libnam 5 mg/2.5 mg tabletMankind Pharma Ltd ₹8.20 71.7% CHEAPER
-
libsana 5mg/2.5mg tabletRyon Pharma ₹9.38 67.7% CHEAPER
-
cromide 5mg/2.5mg tabletLeeford Healthcare Ltd ₹11.72 59.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic stomach problems.
Fact: This medicine is intended for short-term use only. Prolonged use can lead to dependence and withdrawal symptoms. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol increases the sedative effects and can cause severe drowsiness, respiratory depression, and impaired coordination. - Myth: This medicine cures irritable bowel syndrome.
Fact: This medicine provides symptomatic relief but does not cure the underlying condition. Lifestyle and dietary changes are also important.
🔄 Alternative Options
Generic Alternatives
- Clidinium + Chlordiazepoxide combination tablets
Brand Alternatives
- Cibis Tablet
- Clidinium-Chlordiazepoxide Tablet