Colospa Retard Capsule (Mebeverine 200mg): Complete Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain that does not go away
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is cizaspa-sr capsule used for?
This medicine is an antispasmodic used to relieve abdominal pain and cramps in irritable bowel syndrome. It works by relaxing the muscles of the gut. The usual dose is 200 mg three times a day before meals.
- Generic Name: Mebeverine
- Manufacturer: Lupin Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cizaspa-sr capsule के बारे में (Hindi Summary)
उपयोग: यह दवा पेट की ऐंठन, दर्द, सूजन और असहजता को कम करने के लिए इस्तेमाल की जाती है, खासकर इरिटेबल बाउल सिंड्रोम (IBS) में। यह आंतों की मांसपेशियों को आराम देकर काम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, अपच, सिरदर्द, चक्कर आना और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, धड़कन बढ़ना या पेशाब रुकना हो सकता है। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य स्थितियों और एलर्जी के बारे में बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना न लें। शराब से बचें। चक्कर आ सकते हैं, इसलिए वाहन न चलाएं। दवा को पूरा निगलें, चबाएं नहीं।
💊 cizaspa-sr capsule Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal pain, cramps, bloating, and altered bowel habits associated with IBS.","evidence":"Well-established"},{"condition":"Functional bowel disorders","description":"Used to ease gastrointestinal spasms and discomfort in conditions like functional dyspepsia.","evidence":"Moderate"},{"condition":"Gastrointestinal spasms","description":"Helps relax smooth muscle spasms in the gut, providing relief from cramping.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Biliary dyskinesia","description":"Sometimes prescribed to relieve spasms in the biliary tract, though evidence is limited.","evidence":"Limited"},{"condition":"Ureteric colic","description":"Occasionally used off-label for ureteric spasms, but not a standard treatment.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome
Also treats: Functional dyspepsia, Gastrointestinal spasms
📋 Drug Information
| Generic Name(s) | Mebeverine |
| Brand Name | Colospa Retard Capsule |
| Manufacturer | Lupin Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Anti-spasmodics (IBD) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by directly relaxing the smooth muscle of the gastrointestinal tract. It achieves this through a combination of effects: it blocks sodium channels in the smooth muscle cell membrane, which reduces the influx of calcium ions into the cells. This leads to a decrease in the availability of calcium for muscle contraction. Additionally, it may have local anesthetic properties. The net effect is a reduction in abnormal, excessive contractions (spasms) of the gut wall, which helps relieve abdominal pain and cramping. Importantly, this medicine does not affect normal, coordinated bowel movements, so it does not cause constipation or diarrhea. It also does not have systemic anticholinergic effects, making it better tolerated than older antispasmodics.
Mechanism Steps
💡 How to Take cizaspa-sr capsule
Strength: Capsule, 200 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 200 mg capsule taken three times a day, preferably 20 minutes before meals. However, the dose may be adjusted by your doctor based on your condition and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but use with caution due to potential for increased sensitivity to side effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is recommended for patients with renal impairment. However, use with caution in severe renal impairment. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is recommended for patients with mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 600 mg (three 200 mg capsules). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cizaspa-sr capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to mebeverine or any component of the formulation","Paralytic ileus","Severe liver disease"]
⚠️ Warnings & Precautions
["This medicine may cause dizziness. Avoid driving or operating machinery until you know how it affects you.","Do not take this medicine if you are pregnant or breastfeeding without consulting your doctor.","Use with caution in patients with liver or kidney disease.","Do not exceed the recommended dose.","Keep out of reach of children.","If symptoms persist or worsen, consult your doctor."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause central nervous system effects such as excitation, dizziness, and low blood pressure. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before starting this medicine, tell your doctor about all your medical conditions, especially liver or kidney problems, and any allergies you have. Do not take this medicine if you are pregnant or planning to become pregnant without consulting your doctor. If you are breastfeeding, ask your doctor if this medicine is safe for your baby. Avoid drinking alcohol while taking this medicine as it may increase dizziness and drowsiness. This medicine may cause dizziness, so do not drive or operate heavy machinery until you know how it affects you. Take this medicine exactly as prescribed. Do not crush, chew, or open the capsule; swallow it whole with a glass of water. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for your next dose. Do not double the dose. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use it after the expiry date. If your symptoms do not improve after a few weeks or if they get worse, contact your doctor.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, such as dizziness and low blood pressure. Use with caution and monitor for any adverse effects. Dose adjustment may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established, and your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before surgery to avoid potential interactions with anesthetic agents. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It is generally safe, but your dentist may need to take precautions if you are also on other medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness in some people. Avoid strenuous exercise or activities that require balance until you know how the medicine affects you. If you feel dizzy during exercise, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. If affected, avoid driving or operating heavy machinery. Otherwise, it should not significantly impact your daily work or activities. Take it as prescribed to manage your symptoms effectively.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise you on whether to continue, adjust the dose, or stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally considered safe for managing chronic conditions like IBS. However, it is not intended for indefinite use without medical supervision. Regular follow-ups with your doctor are recommended to assess symptom control and adjust treatment as needed. No serious long-term side effects have been reported with mebeverine.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A low-FODMAP diet or avoiding trigger foods can help manage IBS symptoms.
Evidence: Well-establishedYoga, meditation, and counseling can reduce stress-related IBS flare-ups.
Evidence: ModerateCertain probiotic strains may improve gut health and reduce symptoms.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it at your usual times as much as possible. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 1 to 2 hours after taking a dose. However, you may need to take it regularly for a few days to notice significant improvement in your symptoms.
A: Generally, this medicine has few interactions. However, always inform your doctor about all medicines you are taking, including over-the-counter drugs and supplements.
A: The safety of this medicine during pregnancy is not well established. Consult your doctor before taking it if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for cizaspa-sr capsule
View AllAlternative brands with exact same active ingredient:
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clofac plus 200mg tabletIatros Pharmaceuticals Pvt Ltd ₹20.08 89.8% CHEAPER
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normaxin-mb capsule srSystopic Laboratories Pvt Ltd ₹107.81 45% CHEAPER
-
meber 200mg tabletKaizen Research Labs India Pvt Ltd ₹112.50 42.6% CHEAPER
-
mebnorm sr 200 capsuleRidhima Biocare ₹117.19 40.2% CHEAPER
-
overspa mb 200mg capsule prGreen Bract Lifesciences ₹129.00 34.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: It is an antispasmodic that relaxes gut muscles; it does not act like a general painkiller. - Myth: It can cure IBS permanently.
Fact: It provides symptom relief but does not cure the underlying condition. - Myth: It can be taken for any stomach pain.
Fact: It is specifically for spasms and IBS; other causes of stomach pain need different treatment.
🔄 Alternative Options
Generic Alternatives
- Mebeverine 200 mg capsules
Brand Alternatives
- Colospa Retard Capsule