Ciprosyn Tz Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe or worsening abdominal pain
- Sudden pain, swelling, or weakness in the ankle, knee, or shoulder tendon
- Tingling, burning, or numbness in the hands or feet
- Severe watery or bloody diarrhoea with fever
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Yellowing of the skin or eyes, or dark urine
- Palpitations, fainting, or chest discomfort
- Confusion, hallucinations, or a seizure
- Very low urine output or swelling of the legs
If experiencing severe symptoms, call emergency services immediately.
What is ciprosyn tz tablet used for?
This medicine is a prescription oral antibiotic combination of ciprofloxacin and tinidazole. It is used to treat mixed bacterial and protozoal infections of the gut and pelvis. It is taken twice daily with food, and alcohol must be avoided during and for three days after treatment.
- Generic Name: Ciprofloxacin + Tinidazole
- Manufacturer: Synchem Lab
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ciprosyn tz tablet के बारे में (Hindi Summary)
उपयोग: यह दवा दो एंटीबायोटिक दवाओं का संयोजन है, जिसका उपयोग पेट और आंतों के मिश्रित बैक्टीरिया और प्रोटोज़ोआ संक्रमण के इलाज के लिए किया जाता है। यह दस्त, पेचिश, अमीबियासिस, जिआर्डिया संक्रमण और श्रोणि क्षेत्र के कुछ संक्रमणों में दी जाती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और पूरा कोर्स पूरा करना बहुत जरूरी है। इस दवा के साथ शराब बिल्कुल नहीं लेनी चाहिए, क्योंकि इससे उल्टी, चक्कर और दिल की धड़कन तेज हो सकती है। गर्भवती महिलाओं और स्तनपान कराने वाली माताओं को यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा से आमतौर पर मतली, मुँह में धातु जैसा स्वाद, पेट में हल्की तकलीफ, दस्त, सिरदर्द और चक्कर जैसी हल्की समस्याएँ हो सकती हैं। ये आमतौर पर कुछ दिनों में ठीक हो जाती हैं। कभी-कभी टखने या कंधे के टेंडन में दर्द या सूजन, हाथ-पैरों में झनझनाहट, गंभीर दस्त, पीलिया या एलर्जी जैसी गंभीर समस्याएँ भी हो सकती हैं। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: यह दवा सिर्फ डॉक्टर की सलाह पर लें और कोर्स पूरा करें। इसे भोजन के साथ पानी के साथ निगलें। दूध, दही, आयरन, कैल्शियम या एंटासिड के साथ इस दवा को लेने से बचें, क्योंकि इससे दवा का असर कम हो सकता है। शराब बिल्कुल न लें। चक्कर आने पर वाहन न चलाएँ। अगर टेंडन में दर्द, झनझनाहट, गंभीर दस्त या एलर्जी हो तो तुरंत डॉक्टर से संपर्क करें।
💊 ciprosyn tz tablet Uses & Benefits
[{"condition":"Infectious diarrhoea with mixed bacterial and protozoal causes","description":"This medicine is used to treat acute diarrhoea when both bacteria and protozoa such as Giardia or Entamoeba are suspected or confirmed.","evidence":"Well-established"},{"condition":"Amoebic dysentery","description":"Tinidazole clears the amoeba while ciprofloxacin covers secondary bacterial infection in the inflamed bowel.","evidence":"Well-established"},{"condition":"Giardiasis","description":"The tinidazole component is effective against Giardia lamblia, and ciprofloxacin helps with associated bacterial overgrowth.","evidence":"Well-established"},{"condition":"Pelvic inflammatory disease","description":"Used as part of a broader regimen to cover aerobic and anaerobic bacteria in the female reproductive tract.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"Prescribed in some settings for mixed aerobic and anaerobic abdominal infections when a suitable combination is needed.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Bacterial vaginosis","description":"Tinidazole is sometimes used for bacterial vaginosis, and the combination may be chosen when a co-infection is suspected.","evidence":"Limited"},{"condition":"Dental abscess with anaerobic cover","description":"Occasionally prescribed when a dentist or doctor wants combined aerobic and anaerobic coverage before a procedure.","evidence":"Limited"}]
Primary treatment for: Mixed bacterial and protozoal gastrointestinal infections
Also treats: Amoebic dysentery, Giardiasis, Pelvic inflammatory disease, Intra-abdominal infections
📋 Drug Information
| Generic Name(s) | Ciprofloxacin + Tinidazole |
| Brand Name | Alcipro TN 500 mg/600 mg Tablet |
| Manufacturer | Synchem Lab |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Antiprotozoal |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature, between 15 and 30 degrees Celsius, in a dry place away from direct sunlight. Keep the tablets in their original blister pack or container, tightly closed. Do not store in the bathroom or near the kitchen sink. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two separate but complementary antibacterial mechanisms. Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for copying and repairing bacterial DNA. When these enzymes are blocked, the bacterium cannot replicate and dies. Tinidazole is a nitroimidazole that enters anaerobic organisms and is reduced to reactive intermediates. These intermediates damage bacterial DNA and disrupt essential cellular processes, which kills the organism. Because the two ingredients target different organisms and different pathways, the combination provides broader coverage than either agent alone.
Mechanism Steps
💡 How to Take ciprosyn tz tablet
Strength: This medicine is an immediate-release oral tablet. The exact strength of ciprofloxacin and tinidazole is not specified in the available information, so the strength printed on your pack should be confirmed with your pharmacist or doctor.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken by mouth twice a day, morning and evening, with food. The exact strength and duration depend on the type and severity of the infection, your kidney and liver function, and your doctor's assessment. Most courses last between five and ten days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never adjust the dose yourself or stop early without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children and adolescents because of the risk of joint and tendon problems with ciprofloxacin. |
| Elderly Dosage | Older adults may need a lower dose, especially if kidney function is reduced. The risk of tendon problems, nerve symptoms, and heart rhythm changes is higher in people over 65. Kidney function should be checked before starting treatment, and the dose must be individualized by a qualified clinician. |
| Renal Impairment | People with reduced kidney function may need a lower dose or a longer interval between doses of ciprofloxacin. Tinidazole usually does not need adjustment for kidney disease. Kidney function tests should be done before treatment, and the dose must be individualized by a qualified clinician. |
| Hepatic Impairment | People with severe liver disease may need a lower dose or a different medicine, because both ingredients are partly processed by the liver. Liver function should be assessed before treatment, and the dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose depends on the prescribed strength and the individual's kidney and liver function. Do not exceed the dose prescribed by your doctor. For educational reference, the usual adult regimen is one tablet twice daily, but the exact maximum must be confirmed by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ciprosyn tz tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Tizanidine | Major | |
| Theophylline | Major | |
| Warfarin | Major | |
| Amiodarone | Major | |
| Antacids | Moderate | |
| Iron supplements | Moderate | |
| Methotrexate | Moderate | |
| Phenytoin | Moderate | |
| Insulin | Moderate | |
| Caffeine | Minor |
🚨 Major Interactions
- Tizanidine
- Theophylline
- Warfarin
- QT-prolonging drugs such as amiodarone, sotalol, or certain antipsychotics
- Alcohol
⚡ Moderate Interactions
- Antacids, sucralfate, and other aluminium or magnesium salts
- Iron, calcium, zinc, and multivitamins
- Dairy products
- Methotrexate
- Phenytoin
- Oral antidiabetic drugs and insulin
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least three days after the last dose. Tinidazole interferes with the breakdown of alcohol and can cause a disulfiram-like reaction with flushing, severe nausea, vomiting, headache, sweating, and a fast heartbeat. This reaction can be unpleasant and even dangerous. Ciprofloxacin can also add to dizziness and drowsiness, so drinking alcohol increases the chance of falls and accidents.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to ciprofloxacin, tinidazole, or any related antibiotic","Pregnancy","Breastfeeding","Children and adolescents unless specifically advised by a specialist","History of tendon problems caused by fluoroquinolones","Severe liver disease","Use of tizanidine","Alcohol consumption during treatment and for three days after"]
⚠️ Warnings & Precautions
["This medicine can cause tendon inflammation or rupture, especially in people over 60, those taking steroids, and those with kidney or transplant history. Stop and seek help if tendon pain occurs.","It can cause nerve damage with tingling, numbness, or burning in the hands and feet. Report these symptoms promptly.","It can cause dizziness and confusion. Avoid driving or operating machinery until you know how it affects you.","It can cause severe diarrhoea related to Clostridioides difficile. Do not treat diarrhoea with anti-motility drugs without medical advice.","It can cause serious skin reactions. Stop the medicine and seek help for any spreading rash or blistering.","It can worsen muscle weakness in people with myasthenia gravis.","It can cause low or high blood sugar. People with diabetes should monitor closely.","It can cause sensitivity to sunlight. Use sunscreen and avoid prolonged sun exposure."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding because both ingredients pass into breast milk and could affect the baby. If treatment is essential, your doctor may advise temporarily stopping breastfeeding or using a different medicine.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. If someone takes too many tablets, seek emergency medical care immediately. Treatment is supportive and may include stomach emptying if the overdose is recent, along with monitoring of heart rhythm, blood pressure, kidney function, and blood sugar. Do not try to make yourself vomit unless a healthcare professional tells you to.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Never take two doses at the same time to make up for a missed one.
Additional Safety Advice
Take this medicine only when a qualified doctor has prescribed it for you, and complete the full course even if you start feeling better early. Swallow the tablet whole with a full glass of water, and take it with food to reduce stomach upset. Do not drink alcohol during the course and for at least three days after the last dose, because tinidazole can cause a severe flushing reaction with alcohol. Avoid driving or operating heavy machinery if you feel dizzy. Do not take antacids, iron tablets, calcium supplements, or multivitamins within two hours before or after this medicine, as they reduce its absorption. Tell your doctor if you have kidney problems, liver problems, diabetes, epilepsy, or a history of tendon injury. Stop the medicine and seek medical help immediately if you develop tendon pain, numbness, severe diarrhoea, or an allergic reaction.
👴 Special Considerations for Elderly
💡 For Patients Above 65
People over 65 are at higher risk of tendon problems, nerve symptoms, kidney-related side effects, and heart rhythm changes with this medicine. Kidney function should be checked before treatment, and the dose may need to be reduced. Older adults should also be monitored for dizziness and falls, and they should report any new numbness, weakness, or tendon pain immediately.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are trying to conceive, are pregnant, or are breastfeeding. Both ingredients can potentially affect the developing baby. If you are planning pregnancy, discuss safer antibiotic options with your doctor. Use effective contraception during treatment if there is a risk of pregnancy, and inform your doctor immediately if you become pregnant while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may be used after some abdominal or pelvic surgeries when mixed bacterial and anaerobic coverage is needed. It can interact with other medicines used after surgery, such as warfarin and painkillers. Tell your surgical team and anaesthetist about all medicines you are taking. Do not start or stop this medicine after surgery without your surgeon's advice.
🦷 Dental Procedures
This medicine is not a routine choice for dental infections, but it may occasionally be prescribed when a dentist needs combined aerobic and anaerobic coverage. Tell your dentist if you are taking this medicine, especially before any procedure that may involve bleeding, because of the interaction with warfarin and the risk of prolonged bleeding. Do not take leftover tablets for a toothache without medical advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise and heavy lifting while you are unwell with an infection. If you develop tendon pain, swelling, or weakness, stop exercising immediately and seek medical advice. Gentle walking is usually fine once your fever and diarrhoea have settled, but return to your normal routine gradually.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness, headache, and tiredness, especially in the first few days. Avoid driving, operating heavy machinery, or working at heights until you know how the medicine affects you. Most people can continue desk work, but take regular breaks and stay hydrated. If your job involves handling food, you should stay off work until your diarrhoea has fully resolved to avoid spreading infection.
🛑 When to Stop This Medicine
Do not stop this medicine early on your own, even if you feel better, because stopping early can allow the infection to return and can promote antibiotic resistance. Stop the medicine and contact your doctor immediately if you develop tendon pain, numbness or tingling in the hands or feet, severe diarrhoea, an allergic reaction, yellowing of the eyes or skin, or palpitations. Your doctor will decide whether to stop the medicine or change the treatment.
📅 Long-Term Use Effects
This medicine is usually prescribed for a short course of five to ten days, so long-term effects are uncommon. Prolonged or repeated use can increase the risk of antibiotic resistance, gut flora imbalance, fungal infections, and rare nerve or tendon problems. If you need repeated courses, your doctor should review the underlying cause and consider alternative treatments. Regular monitoring of kidney and liver function may be needed in people with existing organ disease.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Replacing lost fluids and salts is essential in any diarrhoeal illness and can be used alongside antibiotics.
Evidence: Well-establishedZinc can reduce the duration and severity of diarrhoea in children, but it does not replace antibiotics when they are needed.
Evidence: Well-establishedSome probiotics may help restore gut flora after antibiotic treatment, but evidence is mixed and they should not replace prescribed antibiotics.
Evidence: LimitedWhen a specific organism is identified, a targeted medicine may be preferred over a broad combination.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no direct interaction between this medicine and routine vaccines. However, if you are unwell with fever or a severe infection, it is better to postpone vaccination until you have recovered. Live vaccines should generally be avoided during acute illness. Discuss the timing of any vaccine with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15 and 30 degrees Celsius
❌ DON'T
Do not refrigerate unless the label says so
✅ DO
Keep the tablets in their original blister pack or container
❌ DON'T
Do not transfer them to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom or near the kitchen sink
✅ DO
Check the expiry date before use
❌ DON'T
Do not use expired tablets
✅ DO
Keep out of reach of children
❌ DON'T
Do not share this medicine with anyone else
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription with you, especially for international travel, because this is a prescription antibiotic. Store the tablets in a cool, dry place away from direct sunlight and do not leave them in a hot car. If you are crossing time zones, keep your doses roughly twelve hours apart and ask your doctor how to adjust the schedule. Avoid alcohol throughout your trip while taking this medicine and for three days after the last dose. Check the customs rules of your destination country for prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Most people notice improvement in fever, diarrhoea, and abdominal pain within 24 to 48 hours. However, you must complete the full prescribed course to fully clear the infection and prevent relapse.
A: Yes, this medicine should be taken with food to reduce stomach upset. Avoid taking it with milk, curd, or calcium-fortified drinks, and keep a two-hour gap from antacids, iron, and calcium supplements.
A: No. Alcohol must be completely avoided during treatment and for at least three days after the last dose, because tinidazole can cause a severe flushing, nausea, and vomiting reaction with alcohol.
A: This medicine is not recommended during pregnancy or breastfeeding. If you are pregnant or planning pregnancy, tell your doctor so that a safer alternative can be chosen.
A: If less than six hours have passed, take the missed dose as soon as you remember. If more than six hours have passed, skip it and take the next dose at the usual time. Never take two doses together.
A: Yes, rarely it can cause tendon pain, swelling, or rupture, especially in people over 60, those taking steroids, and those with kidney disease. Stop the medicine and seek medical help if you notice tendon pain.
🤔 Common Patient Concerns
🔄 Substitutes for ciprosyn tz tablet
View AllAlternative brands with exact same active ingredient:
-
Floxstar T TabletSumac Pharma Pvt Ltd ₹34.10 54.5% CHEAPER
-
trogyl cz ds tabletEspee Formulation Pvt Ltd ₹62.31 16.9% CHEAPER
-
veecin oz tabletVintech Formulations ₹85.00 13.3% COSTLIER
-
ulticept tz tabletConcept Pharmaceuticals Ltd ₹154.69 106.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any stomach upset or loose motion.
Fact: This medicine only works against specific bacteria and protozoa. It does not help with viral diarrhoea, food intolerance, or irritable bowel syndrome. - Myth: You can stop the medicine once you feel better.
Fact: Stopping early can allow the infection to return and can promote antibiotic resistance. Always complete the prescribed course. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a severe flushing and vomiting reaction with tinidazole. It must be avoided during treatment and for three days after. - Myth: This medicine is safe for children.
Fact: Ciprofloxacin is generally avoided in children because of the risk of joint and tendon problems. A specialist must decide if it is needed.
🔄 Alternative Options
Generic Alternatives
- Ciprofloxacin and tinidazole combination tablets from other manufacturers
- Ciprofloxacin tablet plus tinidazole tablet taken separately as prescribed