Cilacar Nb 5 Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Very slow heart rate or fainting
- Severe dizziness or lightheadedness
- Swelling of face, lips, or throat
- Difficulty breathing or wheezing
- Chest pain or worsening heart failure symptoms
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is cinod-n 10/5 tablet used for?
This medicine is a combination of Nebivolol 5 mg and Cilnidipine 10 mg used to treat high blood pressure in adults. It works by relaxing blood vessels and slowing the heart rate. It is taken once daily as prescribed by a doctor.
- Generic Name: Nebivolol + Cilnidipine
- Manufacturer: Ajanta Pharma Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cinod-n 10/5 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें नेबिवोलोल और सिल्निडिपिन दो सक्रिय तत्व हैं जो मिलकर रक्त वाहिकाओं को आराम देते हैं और हृदय की गति को नियंत्रित करते हैं। यह दवा रक्तचाप को कम करके हृदय रोग, स्ट्रोक और किडनी की समस्याओं का खतरा घटाती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान, मतली और टखनों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव जैसे बहुत धीमी हृदय गति, बेहोशी या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें। शराब से बचें क्योंकि इससे चक्कर और ब्लड प्रेशर कम हो सकता है। उठते-बैठते समय धीरे-धीरे उठें। अगर आपको अस्थमा, मधुमेह, लीवर या किडनी की बीमारी है तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना न लें।
💊 cinod-n 10/5 tablet Uses & Benefits
[{"condition":"Essential hypertension","description":"This medicine effectively lowers both systolic and diastolic blood pressure in adults with essential hypertension, especially when monotherapy is insufficient.","evidence":"Well-established"},{"condition":"Hypertension with high sympathetic activity","description":"The combination of nebivolol and cilnidipine helps reduce sympathetic overactivity, which is common in many hypertensive patients.","evidence":"Moderate"},{"condition":"Hypertension with coexisting heart rate concerns","description":"Nebivolol helps control heart rate while cilnidipine provides vasodilation, making this combination useful when tachycardia is a concern.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Angina pectoris","description":"Nebivolol component may be used off-label for angina, but this fixed-dose combination is not approved for that indication.","evidence":"Limited"},{"condition":"Heart failure with reduced ejection fraction","description":"Nebivolol has been studied in heart failure, but this combination is not standard for that use.","evidence":"Limited"}]
Primary treatment for: Essential hypertension
Also treats: Hypertension with tachycardia, Hypertension with high sympathetic activity
📋 Drug Information
| Generic Name(s) | Nebivolol + Cilnidipine |
| Brand Name | Cilacar NB 5 Tablet |
| Manufacturer | Ajanta Pharma Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive (Beta-blocker + Calcium channel blocker) |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Nebivolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. It also promotes nitric oxide-mediated vasodilation. Cilnidipine blocks both L-type and N-type calcium channels, leading to relaxation of peripheral arteries and reduced release of norepinephrine from sympathetic nerve endings. The combined effect lowers blood pressure while maintaining better heart rate control and reducing peripheral edema compared to some other calcium channel blockers.
Mechanism Steps
💡 How to Take cinod-n 10/5 tablet
Strength: Immediate-release oral tablet containing Nebivolol 5 mg and Cilnidipine 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, preferably in the morning. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor blood pressure and heart rate closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be needed. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (nebivolol 5 mg + cilnidipine 10 mg) once daily, unless otherwise directed by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cinod-n 10/5 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| Fluoxetine | Major | |
| Digoxin | Moderate | |
| NSAIDs | Moderate | |
| Ketoconazole | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Verapamil or diltiazem
- Clonidine
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
⚡ Moderate Interactions
- Digoxin
- NSAIDs
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine and cause dizziness, drowsiness, or fainting. It is advisable to avoid alcohol or limit intake while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second- or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe liver disease","Known allergy to nebivolol or cilnidipine"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly; taper gradually under medical supervision.","Use with caution in patients with asthma or COPD.","May mask symptoms of hypoglycemia in diabetic patients.","Avoid in patients with severe peripheral arterial disease.","Use with caution in patients with psoriasis.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe bradycardia, hypotension, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and may include atropine, glucagon, or intravenous fluids as directed by a clinician.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without medical advice, as sudden withdrawal of nebivolol can worsen heart conditions. Avoid alcohol while taking this medicine because it can increase dizziness and low blood pressure. Rise slowly from sitting or lying positions to prevent dizziness. Inform your doctor if you have asthma, diabetes, liver disease, kidney disease, or heart problems. Do not use this medicine during pregnancy or breastfeeding without consulting your doctor. Keep all follow-up appointments for blood pressure and heart rate monitoring.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor blood pressure and heart rate closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy. This medicine may not be suitable during pregnancy, and alternative treatments may be needed.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped temporarily before surgery as advised by your doctor.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may affect blood pressure and heart rate during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid sudden strenuous activity if you feel dizzy or fatigued. Stay hydrated and monitor your heart rate during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when starting treatment. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately for guidance on tapering or switching.
📅 Long-Term Use Effects
Long-term use of this medicine helps control blood pressure and reduces the risk of cardiovascular events. Regular monitoring of blood pressure, heart rate, and kidney/liver function is recommended. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can complement medicine for blood pressure control.
Evidence: Well-establishedYour doctor may consider alternative combinations if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. Continue routine vaccinations as recommended by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing. Carry enough supply for the entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 1 to 2 hours, but full effects may take 1 to 2 weeks of regular use.
A: No, do not stop without consulting your doctor. High blood pressure often requires long-term treatment.
A: Take it as soon as you remember if it is less than 12 hours late. If more than 12 hours, skip the missed dose and continue with your regular schedule.
🤔 Common Patient Concerns
🔄 Substitutes for cinod-n 10/5 tablet
View AllAlternative brands with exact same active ingredient:
-
twinnebi 5 tabletCadila Pharmaceuticals Ltd ₹117.19 SAME PRICE
-
nebifid cn 5mg/10mg tabletFidelity Lifesciences Pvt Ltd ₹120.00 2.4% COSTLIER
-
cilnipres n 5mg/10mg tabletEast West Pharma ₹128.91 10% COSTLIER
-
clindoz-n tabletCare Formulation Labs Pvt Ltd ₹137.00 16.9% COSTLIER
-
maxivas 5mg/10mg tabletHauz Pharma Pvt Ltd ₹140.00 19.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often requires long-term treatment. Stopping suddenly can cause rebound hypertension. - Myth: This medicine causes kidney damage.
Fact: When used as prescribed, it helps protect kidneys by controlling blood pressure.
🔄 Alternative Options
Generic Alternatives
- Nebivolol + Cilnidipine generic tablets
Brand Alternatives
- Cilacar NB 5 Tablet