cimetin 200mg tablet - Cimetidine (200mg) medicine

cimetin 200mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ PCI Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is cimetin 200mg tablet used for?

Acitak (Cimetidine) is used to treat GASTRO INTESTINAL. It contains Cimetidine (200mg), which Competitive antagonist of histamine at H2 receptors, reducing gastric acid secre. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cimetidine
  • Manufacturer: PCI Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cimetin 200mg tablet Uses & Benefits

Duodenal ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, prevention of stress ulcers, prophylaxis of aspiration pneumonitis.

Off-label uses: Hirsutism (due to antiandrogen effects), chronic urticaria, adjunct in cancer immunotherapy (due to immunomodulation).

๐Ÿ“‹ Drug Information

Generic Name(s)Cimetidine
Brand NameAcitak
ManufacturerPCI Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassH2 Receptor Blocker
Route of AdministrationOral, intravenous, intramuscular.
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations achieved within 1-2 hours.
DistributionWidely distributed throughout body tissues; crosses the blood-brain barrier and placenta.
Protein BindingApproximately 20% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via oxidation, hydroxylation, and sulfoxidation.
Half-LifeApproximately 2 hours (normal renal function); prolonged in renal impairment.
ExcretionPrimarily excreted in urine (50-70% as unchanged drug and metabolites); some biliary excretion.
BioavailabilityApproximately 60-70% after oral administration.
Onset of ActionWithin 1 hour after oral administration.
Peak Plasma Time1-2 hours after oral administration.
Duration of Action4-6 hours (dose-dependent).

How It Works

Competitive antagonist of histamine at H2 receptors, reducing gastric acid secretion.

Mechanism Steps

1Cimetidine binds competitively to histamine H2 receptors on gastric parietal cells.
2Blockade of H2 receptors inhibits adenylate cyclase activity, reducing cyclic AMP production.
3Decreased cyclic AMP leads to reduced activation of protein kinase A.

๐Ÿ’ก How to Take cimetin 200mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cimetin 200mg tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Diarrhea
  • Constipation
  • Nausea
  • Vomiting
  • Rash

๐Ÿšจ Serious Side Effects

  • Confusion
  • Hallucinations
  • Seizures
  • Arrhythmias
  • Hepatitis
  • Interstitial nephritis
  • Agranulocytosis
  • Thrombocytopenia
  • Pancreatitis

โš ๏ธ Rare Side Effects

  • Gynecomastia
  • Impotence
  • Loss of libido
  • Alopecia
  • Myalgia
  • Arthralgia
  • Fever

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk due to inhibition of warfarin metabolism.
Theophylline Major Increased theophylline levels, risk of toxicity.
Phenytoin Major Increased phenytoin levels, risk of toxicity.
Lidocaine Major Increased lidocaine levels, risk of cardiotoxicity.
Quinidine Major Increased quinidine levels, risk of arrhythmias.
Propranolol Major Increased propranolol levels, enhanced beta-blockade.
Metoprolol Major Increased metoprolol levels, enhanced beta-blockade.
Carbamazepine Major Increased carbamazepine levels, risk of toxicity.
Tricyclic antidepressants Major Increased TCA levels, risk of anticholinergic effects.
Benzodiazepines Major Increased benzodiazepine levels, enhanced sedation.
Calcium channel blockers Moderate Increased CCB levels, enhanced hypotensive effect.
Sulfonylureas Moderate Increased sulfonylurea levels, risk of hypoglycemia.
Metformin Moderate Increased metformin levels, risk of lactic acidosis.
Procainamide Moderate Increased procainamide levels, risk of arrhythmias.
Flecainide Moderate Increased flecainide levels, risk of arrhythmias.
Morphine Moderate Increased morphine levels, enhanced respiratory depression.
Caffeine Moderate Increased caffeine levels, enhanced stimulant effects.
Alcohol Moderate Increased blood alcohol levels, enhanced intoxication.
Antacids Minor Reduced absorption of cimetidine if taken simultaneously; separate by 1 hour.
Sucralfate Minor Reduced absorption of cimetidine; separate by 1 hour.
Ketoconazole Minor Reduced absorption of ketoconazole due to increased gastric pH.
Itraconazole Minor Reduced absorption of itraconazole due to increased gastric pH.
Tetracyclines Minor Reduced absorption of tetracyclines due to increased gastric pH.
Iron supplements Minor Reduced absorption of iron due to increased gastric pH.

๐Ÿšจ Major Interactions

  • Warfarin
  • Theophylline
  • Phenytoin
  • Lidocaine
  • Quinidine
  • Propranolol
  • Metoprolol
  • Carbamazepine
  • Tricyclic antidepressants
  • Benzodiazepines (e.g., diazepam, chlordiazepoxide)

โšก Moderate Interactions

  • Calcium channel blockers (e.g., nifedipine)
  • Sulfonylureas (e.g., glipizide)
  • Metformin
  • Procainamide
  • Flecainide
  • Morphine
  • Caffeine
  • Alcohol

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate
  • Ketoconazole
  • Itraconazole
  • Tetracyclines
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect bioavailability; avoid high-protein meals as they may increase gastric acid stimulation.

๐Ÿท Alcohol Interaction

Cimetidine may increase blood alcohol levels by inhibiting alcohol dehydrogenase; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cimetidine or any component; use with caution in elderly, renal impairment, hepatic impairment.

๐Ÿ“Š Monitoring Parameters

Gastric pH, renal function, hepatic function, CBC, drug levels for interacting medications (e.g., warfarin, theophylline).

๐Ÿคฑ Lactation Safety

Cimetidine is excreted in breast milk; caution advised; alternative agents preferred.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; monitor vital signs and ECG; dialysis may be effective.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cimetin 200mg tablet

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Alternative brands with exact same active ingredient (Cimetidine (200mg)):

Medical Note: Always consult your doctor before switching medications.

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