cifran 100 tablet - Ciprofloxacin (100mg) medicine

cifran 100 tablet

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🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

What is cifran 100 tablet used for?

This medicine contains Ciprofloxacin (100mg) and is used to treat GASTRO INTESTINAL. Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventing DNA replication, t. Always consult your doctor before use.

  • Generic Name: Ciprofloxacin
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 cifran 100 tablet Uses & Benefits

Urinary tract infections, respiratory tract infections, skin and soft tissue infections, bone and joint infections, gastrointestinal infections, septicemia, and anthrax.

Off-label uses: Prostatitis, epididymitis, pelvic inflammatory disease, and some mycobacterial infections.

📋 Drug Information

Generic Name(s)Ciprofloxacin
Brand NameAlciflox 500mg Tablet
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOral
StorageStore at room temperature (20-25°C), protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionRapidly and well absorbed from the gastrointestinal tract after oral administration.
DistributionWidely distributed throughout the body; high concentrations in tissues and fluids including lung, sinus, bone, prostate, and urine.
Protein Binding20-40%
MetabolismPartially metabolized in the liver; produces four metabolites (desethylene-, sulfonyl-, oxo-, and N-formylciprofloxacin).
Half-Life4 hours (range 3-5 hours)
ExcretionPrimarily excreted unchanged in urine (50-70%) via glomerular filtration and tubular secretion; also in feces (15-25%).
Bioavailability70-80%
Onset of Action1-2 hours
Peak Plasma Time1-2 hours
Duration of Action12 hours

How It Works

Inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventing DNA replication, transcription, repair, and recombination.

Mechanism Steps

1Ciprofloxacin enters bacterial cell via porin channels.
2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV.
3Inhibits the resealing of DNA strands after cleavage.
4Prevents DNA replication, transcription, repair, and recombination.
5Leads to bacterial cell death.

💡 How to Take cifran 100 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of cifran 100 tablet

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Insomnia
Abdominal pain

🚨 Serious Side Effects

Tendonitis or tendon rupture
Peripheral neuropathy
CNS effects (seizures, confusion)
QT prolongation
Clostridium difficile diarrhea
Hypersensitivity reactions

⚠️ Rare Side Effects

Hemolytic anemia
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Interstitial nephritis
Hepatitis
Photosensitivity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tizanidine Major Increased risk of hypotension and sedation
Theophylline Major Increased theophylline levels, risk of toxicity
Warfarin Major Increased anticoagulant effect, bleeding risk
Caffeine Major Increased caffeine levels, CNS stimulation
NSAIDs Major Increased risk of CNS stimulation and seizures
Cyclosporine Moderate Increased nephrotoxicity risk
Methotrexate Moderate Increased methotrexate toxicity
Phenytoin Moderate Altered phenytoin levels
Glyburide Moderate Increased hypoglycemic effect
Probenecid Moderate Decreased renal excretion of ciprofloxacin
Diazepam Minor Possible increased diazepam effect
Metoprolol Minor Possible increased metoprolol effect
Omeprazole Minor Possible decreased ciprofloxacin absorption
Ranitidine Minor Possible decreased ciprofloxacin absorption

🚨 Major Interactions

  • Tizanidine
  • Theophylline
  • Warfarin
  • Caffeine
  • NSAIDs

⚡ Moderate Interactions

  • Cyclosporine
  • Methotrexate
  • Phenytoin
  • Glyburide
  • Probenecid

🍷 Alcohol Interaction

No direct interaction, but alcohol may increase CNS side effects like dizziness.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to ciprofloxacin or any fluoroquinolone; concomitant use with tizanidine; history of tendon disorders related to fluoroquinolones.

🤱 Lactation Safety

Excreted in breast milk; use with caution, potential for adverse effects in nursing infants.

💊 Overdose Management

Supportive care; monitor ECG for QT prolongation; consider activated charcoal if recent ingestion; hemodialysis removes only 10-20%.

⏰ Missed Dose

Take as soon as remembered unless near next dose; skip missed dose if close to next dose; do not double dose.

🔄 Substitutes for cifran 100 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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