Dexoren S Eye/Ear Drops: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden vision loss or severe eye pain
- Swelling of the face, lips, or throat
- High fever with worsening eye or ear pain
- Severe headache with neck stiffness
- Unusual bruising, bleeding, or extreme tiredness
- New discharge or worsening redness after starting the medicine
- Ringing in the ears or hearing loss
If experiencing severe symptoms, call emergency services immediately.
What is chlorocol d eye drop used for?
This medicine is a prescription eye and ear drop that combines chloramphenicol, an antibiotic, with dexamethasone, a steroid. It treats bacterial eye or ear infections that also have inflammation. Use it only as prescribed, usually for a short time, and do not use it if you have a viral or fungal eye infection or a perforated eardrum.
- Generic Name: Chloramphenicol + Dexamethasone
- Manufacturer: Jawa Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 chlorocol d eye drop के बारे में (Hindi Summary)
उपयोग: यह दवा आंख और कान की बूंदों के रूप में इस्तेमाल होती है। इसमें क्लोरैम्फेनिकॉल नाम का एंटीबायोटिक और डेक्सामेथासोन नाम का स्टेरॉयड होता है। यह बैक्टीरिया से होने वाले आंख या कान के संक्रमण में दी जाती है, जब सूजन, लालिमा और खुजली भी हो। यह बैक्टीरिया को मारती है और सूजन कम करती है। इसे डॉक्टर के कहे अनुसार ही आंख या कान में डालें। वायरल या फंगल संक्रमण, या कान का पर्दा फटा होने पर इसका इस्तेमाल न करें।
साइड इफेक्ट्स: इस दवा से आमतौर पर हल्की जलन, खुजली या अस्थायी धुंधलापन हो सकता है। कुछ लोगों को आंख में बूंद डालने के बाद मुंह में कड़वा स्वाद आ सकता है। अगर आंख या कान में तेज दर्द, सूजन, रंगत में बदलाव, या धुंधलापन लंबे समय तक रहे, तो डॉक्टर से मिलें। बहुत कम मामलों में गंभीर एलर्जी या खून से जुड़ी समस्या हो सकती है, इसलिए असामान्य थकान, बुखार या नील पड़ने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा का इस्तेमाल डॉक्टर की सलाह से ही करें। बूंद डालने से पहले और बाद में हाथ धोएं। ड्रॉपर की नोक को आंख, कान या किसी सतह से न छुएं। कॉन्टैक्ट लेंस पहनते हैं तो बूंद डालने से पहले निकाल दें और 15 मिनट बाद ही लगाएं। दवा को ठंडी, सूखी जगह पर रखें और धूप से बचाएं। गर्भवती महिलाएं, स्तनपान कराने वाली महिलाएं और छोटे बच्चे इसका इस्तेमाल डॉक्टर की सलाह के बिना न करें।
💊 chlorocol d eye drop Uses & Benefits
[{"condition":"Bacterial conjunctivitis with inflammation","description":"Used to treat bacterial infection of the conjunctiva when redness, swelling, and discharge are also present.","evidence":"Well-established"},{"condition":"Bacterial blepharitis","description":"Helps control bacterial infection and inflammation of the eyelid margins.","evidence":"Well-established"},{"condition":"Bacterial keratitis or corneal ulcer (selected cases)","description":"May be used for certain bacterial corneal infections when a doctor decides the anti-inflammatory effect is needed.","evidence":"Limited"},{"condition":"External ear infection (otitis externa) with inflammation","description":"Used in the ear canal for bacterial infection accompanied by swelling and itching.","evidence":"Well-established"},{"condition":"Post-operative eye inflammation with bacterial cover","description":"Sometimes prescribed after eye surgery to reduce inflammation and prevent bacterial infection.","evidence":"Limited"}]
Off-label uses: [{"condition":"Allergic eye inflammation with suspected bacterial infection","description":"Occasionally used when allergy and bacterial infection are both suspected, but this is not a standard first choice.","evidence":"Limited"},{"condition":"Chronic ear canal dermatitis with bacterial infection","description":"May be used for inflamed ear canal skin when bacterial infection is also present.","evidence":"Limited"}]
Primary treatment for: Bacterial eye or ear infections with inflammation
Also treats: Bacterial conjunctivitis, Bacterial blepharitis, Otitis externa
📋 Drug Information
| Generic Name(s) | Chloramphenicol + Dexamethasone |
| Brand Name | Biodexone C Eye Drop |
| Manufacturer | Jawa Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL OTOLOGICALS |
| Action Class | Antibiotic + Corticosteroid |
| Route of Administration | Topical (ophthalmic and otic). This medicine is placed directly into the affected eye or ear as directed by a clinician |
| Storage | Store at room temperature between 15°C and 30°C. Keep the bottle tightly closed. Protect from light and moisture. Do not freeze. Keep out of reach of children. |
| Shelf Life | Usually 24 months from the date of manufacture, or as printed on the label. Do not use after the expiry date. Once opened, follow the manufacturer's instructions for how long the bottle may be used. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works in two ways. Chloramphenicol enters bacterial cells and binds to the 50S subunit of the bacterial ribosome, blocking the formation of peptide bonds. This stops bacteria from making proteins they need to survive and multiply. Dexamethasone is a corticosteroid that binds to glucocorticoid receptors inside cells. This binding reduces the production of inflammatory chemicals such as prostaglandins and leukotrienes, which decreases swelling, redness, itching, and allergic reactions in the eye or ear. The antibiotic controls the bacterial infection while the steroid calms the inflamed tissue.
Mechanism Steps
💡 How to Take chlorocol d eye drop
Strength: Eye and ear drops containing chloramphenicol 0.5% w/v and dexamethasone 0.1% w/v.
Dosage Information
| Adult Dosage | The usual adult dose is 1 to 2 drops placed into the affected eye or ear every 4 to 6 hours, or as directed by your doctor. For eye infections, the frequency may be higher for the first 1 to 2 days and then reduced. For ear infections, the drops are usually placed in the ear canal while lying on your side. The exact dose and duration depend on the type and severity of the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use more or longer than prescribed. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is generally not recommended for children under 2 years unless a doctor specifically prescribes it. |
| Elderly Dosage | Older adults usually use the same dose as younger adults. However, because the risk of eye pressure rise and cataract is higher with steroid eye drops, elderly patients should have regular eye checks if this medicine is used for more than a few days. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is usually needed for kidney problems with topical eye or ear use. Tell your doctor if you have kidney disease. |
| Hepatic Impairment | No specific dose adjustment is usually needed for liver problems with topical eye or ear use. Tell your doctor if you have liver disease, especially if you use this medicine for a long time. |
| Maximum Daily Dose | The maximum daily dose depends on the prescribed frequency and the condition being treated. Do not exceed the number of drops or the number of days your doctor has prescribed. For adults, a common maximum is 1 to 2 drops in the affected eye or ear up to 6 times a day, but this must be confirmed by your clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of chlorocol d eye drop
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Other corticosteroid eye or ear drops | Major | |
| Other chloramphenicol or antibiotic eye or ear drops | Major | |
| Ketoconazole | Moderate | |
| Itraconazole | Moderate | |
| Ritonavir | Moderate | |
| Rifampicin | Moderate | |
| Carbamazepine | Moderate | |
| Phenytoin | Moderate | |
| Live vaccines | Moderate | |
| Contact lens solutions | Minor |
🚨 Major Interactions
- Other eye or ear drops containing corticosteroids
- Other eye or ear drops containing chloramphenicol or other antibiotics
⚡ Moderate Interactions
- CYP3A4 inhibitors such as ketoconazole, itraconazole, or ritonavir
- CYP3A4 inducers such as rifampicin, carbamazepine, or phenytoin
- Live vaccines
🍷 Alcohol Interaction
Alcohol is not expected to interact directly with this eye or ear medicine because systemic absorption is low. However, if you drink alcohol heavily, it can affect your immune system and liver. Tell your doctor if you drink alcohol regularly, especially if you use this medicine for a long time or have liver problems.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Allergy to chloramphenicol, dexamethasone, or any ingredient in this medicine.","Viral eye infections such as herpes simplex keratitis.","Fungal eye or ear infections.","Untreated bacterial eye infection where the infection is not controlled.","Perforated eardrum or ear drainage through a hole in the eardrum.","Tuberculosis of the eye.","Use in children under 2 years unless specifically prescribed by a doctor."]
⚠️ Warnings & Precautions
["Do not use this medicine for more than the recommended number of days without a doctor's check.","Corticosteroids can mask signs of infection and make some infections worse.","Prolonged use can raise eye pressure and cause glaucoma or cataract.","Do not touch the dropper tip to any surface to avoid contamination.","Do not use this medicine while wearing contact lenses unless your doctor approves.","Tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.","Tell your doctor about all other medicines, eye drops, or ear drops you use.","Stop using this medicine and call your doctor if symptoms get worse or new symptoms appear."]
🤱 Lactation Safety
It is not known whether chloramphenicol or dexamethasone from eye or ear drops passes into breast milk in amounts that could affect a nursing baby. Because systemic absorption is low, risk is expected to be small, but consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose from eye or ear drops is unlikely because the amount used is small. If someone accidentally swallows this medicine, rinse the mouth and contact a poison control center or emergency room right away. Do not try to make the person vomit unless a medical professional tells you to do so.
⏰ Missed Dose
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not use a double dose to make up for a missed one.
Additional Safety Advice
Use this medicine exactly as your doctor prescribed. Wash your hands before and after each use. Do not touch the dropper tip to your eye, ear, eyelid, or any surface, because that can contaminate the bottle. If you wear contact lenses, remove them before using eye drops and wait at least 15 minutes before putting them back, unless your doctor says otherwise. Do not use this medicine for more than the recommended number of days without a follow-up check. Do not share this medicine with anyone else. Keep the bottle closed tightly and store it as directed on the label. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before using this medicine. Do not use this medicine if the seal is broken or the liquid looks cloudy or has particles.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the effects of steroid eye drops, especially raised eye pressure and cataract. If this medicine is used for more than a few days, regular eye checks are recommended. Elderly patients should also tell their doctor about all other medicines they take.
🤰 Pregnancy Planning (TTC)
If you are trying to become pregnant, tell your doctor before using this medicine. The safety of chloramphenicol and dexamethasone eye or ear drops during pregnancy is not fully established. Use only if your doctor decides it is clearly needed.
🏥 Post-Surgery Considerations
This medicine may sometimes be prescribed after eye surgery to reduce inflammation and prevent infection. Use it exactly as your surgeon directs. Do not use it after ear surgery unless your surgeon specifically prescribes it. Keep all follow-up appointments.
🦷 Dental Procedures
This medicine is not expected to affect dental procedures. However, tell your dentist about all medicines you use, including eye and ear drops, before any dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can usually continue light exercise while using this medicine. Avoid swimming until the eye or ear infection has cleared, because water can worsen the infection. If you have blurred vision after eye drops, wait until it clears before doing activities that need clear vision, such as cycling or lifting weights.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause temporary blurred vision after eye drops, so wait until your vision is clear before driving or operating heavy machinery. Most people can continue their usual work and daily activities. If you have eye pain or sensitivity to light, take breaks from screen work and use sunglasses outdoors.
🛑 When to Stop This Medicine
Stop using this medicine when your doctor tells you to stop, or when the prescribed course is finished. If you develop severe eye pain, vision changes, swelling of the face or throat, or a new infection, stop the medicine and seek medical help immediately. Do not stop early without asking your doctor, because the infection may return.
📅 Long-Term Use Effects
Long-term use of this medicine can raise eye pressure, leading to glaucoma, and can cause cataract. It can also increase the risk of secondary infections and slow healing. Because it contains chloramphenicol, very rare blood problems may occur, mainly with systemic use. Regular eye checks are needed if this medicine is used for more than a few days. Do not use it for a long time without a doctor's supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A clean, warm compress can help relieve discomfort and loosen discharge in bacterial conjunctivitis.
Evidence: LimitedAvoiding water in the ear canal helps otitis externa heal and prevents recurrence.
Evidence: Well-establishedFor simple bacterial eye infection without much inflammation, a doctor may choose an antibiotic-only drop.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine is applied to the eye or ear, so it is not expected to affect vaccines. However, if you use steroid-containing medicines for a long time, your doctor may consider the timing of live vaccines. Discuss any vaccine plans with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not freeze or refrigerate unless the label says to do so
✅ DO
Keep the bottle tightly closed and in its original carton
❌ DON'T
Do not transfer the drops to another container
✅ DO
Keep away from direct sunlight and heat
❌ DON'T
Do not store in a hot car or near a stove
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label visible. Keep a copy of your prescription with you, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If you are crossing time zones, continue your usual dosing schedule as closely as possible, but do not double up on doses. Check the expiry date before you travel. If you need to use it on a plane, keep it in your hand luggage and follow airline rules for liquids.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may notice some improvement in redness and discomfort within 1 to 2 days. The infection usually improves over 3 to 7 days. If there is no improvement after 2 to 3 days, contact your doctor.
A: Do not stop early unless your doctor tells you to. Stopping too soon can let the infection come back. Follow the full course prescribed.
A: Use it only in the eye or ear your doctor has specified. Do not use the same bottle for both eyes or both ears unless your doctor says it is safe.
A: It is generally not recommended for children under 2 years unless a doctor specifically prescribes it. For older children, the dose must be decided by a doctor.
A: Remove contact lenses before using eye drops and wait at least 15 minutes before putting them back, unless your doctor tells you otherwise.
🤔 Common Patient Concerns
🔄 Substitutes for chlorocol d eye drop
View AllAlternative brands with exact same active ingredient:
-
phenimax dm eye dropHamax Pharmaceuticals ₹8.21 10.1% CHEAPER
-
eptico d eye/ear dropsElder Pharmaceuticals Ltd ₹9.06 0.8% CHEAPER
-
biodexone c eye dropBiochem Pharmaceutical Industries ₹9.86 8% COSTLIER
-
chlormet dm eye dropSun Pharmaceutical Industries Ltd ₹11.02 20.7% COSTLIER
-
renidex eye/ear dropsKlar Sehen Pvt Ltd ₹11.02 20.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any red eye.
Fact: This medicine contains a steroid and an antibiotic. It should not be used for viral or allergic eye problems unless a doctor specifically prescribes it. - Myth: More drops will make it work faster.
Fact: Using more drops than prescribed can increase side effects and does not speed up healing. - Myth: It is safe to use for weeks without a check-up.
Fact: Prolonged use can raise eye pressure, cause cataract, and increase infection risk. Follow your doctor's instructions on duration. - Myth: This medicine can be used in the ear even if the eardrum is perforated.
Fact: It should not be used if the eardrum is perforated because it can harm the inner ear.
🔄 Alternative Options
Generic Alternatives
- Chloramphenicol 0.5% w/v + Dexamethasone 0.1% w/v eye/ear drops
Brand Alternatives
- Dexoren S Eye/Ear Drops