Abmef-DS 500mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash with blisters or peeling
- Persistent fever or sore throat
If experiencing severe symptoms, call emergency services immediately.
What is cetameff tablet used for?
This medicine is a combination of mefenamic acid (an NSAID) and paracetamol (an analgesic) used for short-term relief of moderate to severe pain, such as musculoskeletal pain, dental pain, and menstrual cramps. It works by reducing inflammation and blocking pain signals. Take it with food to avoid stomach upset and do not exceed the prescribed dose.
- Generic Name: Mefenamic Acid + Paracetamol
- Manufacturer: Nova Indus Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cetameff tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेफेनामिक एसिड और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, मासिक धर्म के दर्द, और सर्जरी के बाद के दर्द में राहत देती है। यह सूजन को कम करती है और दर्द को शांत करती है। इसे भोजन के साथ लें और डॉक्टर के बताए अनुसार ही सेवन करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत की क्षति, और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, या त्वचा का पीलापन दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक से अधिक न लें। इसे भोजन या दूध के साथ लें ताकि पेट की जलन कम हो। इस दवा के साथ शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे या यकृत की बीमारी है, तो डॉक्टर से परामर्श करें। इस दवा से नींद या चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीनरी चलाने से बचें।
💊 cetameff tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of pain after minor surgeries.","evidence":"Well-established"},{"condition":"Menstrual cramps (dysmenorrhea)","description":"Reduces pain and cramping associated with menstruation.","evidence":"Well-established"},{"condition":"Headache","description":"May be used for tension headaches, but not typically for migraines.","evidence":"Moderate"},{"condition":"Fever","description":"Paracetamol component helps reduce fever, but this combination is not primarily used for fever alone.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Osteoarthritis flare-ups","description":"May be used short-term for pain relief during flare-ups, but not for long-term management.","evidence":"Limited"}]
Primary treatment for: Acute pain and inflammation
Also treats: Dysmenorrhea, Musculoskeletal pain, Dental pain, Post-operative pain, Headache
📋 Drug Information
| Generic Name(s) | Mefenamic Acid + Paracetamol |
| Brand Name | Abmef-DS Oral Suspension |
| Manufacturer | Nova Indus Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Mefenamic acid is a non-steroidal anti-inflammatory drug (NSAID) that reversibly inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, leading to analgesia and antipyresis. The combination provides additive pain relief.
Mechanism Steps
💡 How to Take cetameff tablet
Strength: Each tablet contains Mefenamic Acid 500 mg and Paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally two to three times daily, as needed for pain. The maximum recommended dose is 3 tablets in 24 hours. The dose should be individualized by a qualified clinician based on the indication, severity of pain, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose. Use for the shortest duration necessary to control symptoms. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal bleeding, renal impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. Avoid in severe renal impairment (creatinine clearance <30 mL/min). Consult a doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Avoid in severe hepatic impairment. Consult a doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose is 3 tablets (1500 mg mefenamic acid and 975 mg paracetamol) in 24 hours. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cetameff tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Antacids | Moderate | |
| Cholestyramine | Moderate | |
| Metoclopramide | Moderate |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Antacids
- Cholestyramine
- Metoclopramide
- Probenecid
- Rifampicin
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can potentiate liver toxicity, especially due to the paracetamol component. It may also increase drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to mefenamic acid, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active or history of peptic ulcer or gastrointestinal bleeding.","Severe renal impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Cardiovascular risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke. Use the lowest effective dose for the shortest duration.","Gastrointestinal risk: NSAIDs can cause serious gastrointestinal adverse events, including bleeding, ulceration, and perforation, which can be fatal. Use with caution in the elderly and those with a history of GI disease.","Renal effects: Long-term use may lead to kidney injury. Monitor renal function in at-risk patients.","Hepatic effects: Paracetamol overdose can cause hepatotoxicity. Do not exceed the recommended dose. Avoid alcohol.","Skin reactions: Serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported with NSAIDs. Discontinue at the first sign of rash.","Haematological effects: Mefenamic acid may cause blood dyscrasias. Monitor CBC if prolonged use.","Use in elderly: Increased risk of GI bleeding, renal impairment, and cardiovascular events. Use with caution.","Use in pregnancy: Avoid in the third trimester. Consult doctor before use.","Driving and operating machinery: May cause dizziness or drowsiness. Avoid until you know how it affects you."]
🤱 Lactation Safety
Mefenamic acid and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use. Monitor the infant for any unusual signs.
💊 Overdose Management
Overdose of this medicine can cause severe nausea, vomiting, abdominal pain, drowsiness, and potentially life-threatening liver damage (from paracetamol) and kidney damage (from mefenamic acid). If overdose is suspected, seek emergency medical attention immediately. Treatment includes activated charcoal if within 1-2 hours of ingestion, administration of N-acetylcysteine for paracetamol toxicity, and supportive care. Monitor liver and kidney function, and provide symptomatic treatment.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not take other medicines containing paracetamol or other NSAIDs without consulting your doctor. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. This medicine may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how it affects you. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at increased risk of gastrointestinal bleeding, renal impairment, and cardiovascular events with NSAID use. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid concurrent use with other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like mefenamic acid may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Paracetamol is considered relatively safe when used as directed.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain management. However, it should be used with caution after surgery due to the risk of bleeding and renal impairment. Follow your surgeon's instructions regarding pain management.
🦷 Dental Procedures
This medicine can be used for dental pain, including after dental procedures. Inform your dentist about all medicines you are taking. Avoid taking additional paracetamol-containing products to prevent liver toxicity.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require mental alertness until you know how the medicine affects you. If you have musculoskeletal pain, consult a physiotherapist for appropriate exercises.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset; taking it with food can help. If your work involves physical labor, take precautions to avoid injury.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your pain does not improve within 7 days, if it worsens, or if you experience any serious side effects such as gastrointestinal bleeding, severe abdominal pain, or allergic reactions. Do not stop abruptly if you are on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of serious gastrointestinal, cardiovascular, and renal adverse events. It may cause peptic ulcers, gastrointestinal bleeding, kidney impairment, and increased cardiovascular risk. Regular monitoring of renal and hepatic function, complete blood count, and gastrointestinal symptoms is recommended for patients on prolonged therapy. Use the lowest effective dose for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve mobility.
Evidence: Well-establishedMay help reduce pain and inflammation in musculoskeletal conditions.
Evidence: ModerateMay provide pain relief for some individuals.
Evidence: LimitedCan help manage chronic pain and reduce stress.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing intervals as advised by your doctor. Check local customs regulations regarding prescription medicines. Always carry enough supply for your trip and keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it orally.
A: This medicine is intended for short-term use only, typically not exceeding 7 days unless directed by your doctor. Prolonged use increases the risk of side effects.
A: No, you should avoid alcohol while taking this medicine as it increases the risk of liver damage and gastrointestinal bleeding.
A: NSAIDs like mefenamic acid are generally avoided during the third trimester of pregnancy. Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine may be used for tension headaches, but it is not typically the first choice. Consult your doctor for appropriate treatment.
A: Yes, this medicine can cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
A: Do not take this medicine with other NSAIDs or paracetamol-containing products without consulting your doctor, as it can increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for cetameff tablet
View AllAlternative brands with exact same active ingredient:
-
mef-plus tabletZeelab Pharmacy Pvt Ltd ₹22.50 72.6% CHEAPER
-
mefrite p 500mg/325mg tabletMHS Pharmaceuticals Pvt Ltd ₹25.00 69.5% CHEAPER
-
stayhappi mefenamic acid+paracetamol 500mg/325mg tabletSarvagunaushdhi Pvt Ltd ₹25.31 69.1% CHEAPER
-
mflocid forte 500mg/325mg tabletFloreat Medica Pvt Ltd ₹29.44 64.1% CHEAPER
-
mefwal forte 500mg/325mg tabletWallace Pharmaceuticals Pvt Ltd ₹30.00 63.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take for any type of pain.
Fact: This medicine is intended for short-term relief of moderate to severe pain. It is not suitable for all types of pain and should only be used as prescribed. - Myth: You can take this medicine on an empty stomach.
Fact: Taking this medicine on an empty stomach increases the risk of stomach upset and gastrointestinal bleeding. Always take it with food or milk. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of liver damage and gastrointestinal bleeding. Avoid alcohol while taking this medicine. - Myth: This medicine is safe to use during pregnancy.
Fact: NSAIDs like mefenamic acid are generally avoided during the third trimester of pregnancy. Consult your doctor before use. - Myth: You can double the dose if the pain is severe.
Fact: Never exceed the recommended dose. Taking more than prescribed can lead to serious side effects. Consult your doctor if pain is not controlled.
🔄 Alternative Options
Generic Alternatives
- Mefenamic Acid + Paracetamol
Brand Alternatives
- Abmef-DS 500mg/325mg Tablet