ceso 20mg tablet

4.3 (10 reviews)

Esomeprazole (20mg)

🏭 Comed Chemicals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is ceso 20mg tablet used for?

Adyom 40mg Tablet (Esomeprazole) is used to treat GASTRO INTESTINAL. It contains Esomeprazole (20mg), which Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion b. Always consult your doctor before use. Take as prescribed.

Generic Name: Esomeprazole
Manufacturer: Comed Chemicals Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 ceso 20mg tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), erosive esophagitis, Zollinger-Ellison syndrome, Helicobacter pylori eradication (in combination), peptic ulcer disease, prevention of NSAID-induced ulcers.

Off-label uses: Laryngopharyngeal reflux, prevention of stress ulcers in critically ill patients, eosinophilic esophagitis.

📋 Drug Information

Generic Name(s)	Esomeprazole
Brand Name	Adyom 40mg Tablet
Manufacturer	Comed Chemicals Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Proton pump inhibitors
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from moisture and light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached within 1-2 hours. Food may delay absorption but does not affect extent.

DistributionVolume of distribution approximately 16 L; extensively distributed into tissues.

Protein Binding97% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes; major metabolites are hydroxy, desmethyl, and sulfone derivatives.

Half-LifeApproximately 1-1.5 hours in healthy subjects; may be prolonged in hepatic impairment.

ExcretionApproximately 80% excreted as metabolites in urine, the remainder in feces.

BioavailabilityApproximately 64% after a single oral dose; may increase with repeated dosing.

Onset of Action1-4 hours for acid suppression.

Peak Plasma Time1-2 hours.

Duration of ActionUp to 24 hours.

How It Works

Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell.

Mechanism Steps

1Esomeprazole accumulates in the acidic environment of gastric parietal cell canaliculi.

2Protonation occurs to form the active sulfenamide metabolite.

3Active metabolite binds covalently to cysteine residues of the H+/K+-ATPase enzyme.

💡 How to Take ceso 20mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of ceso 20mg tablet

✅ Common Side Effects

Headache
Abdominal pain
Nausea
Diarrhea
Constipation
Flatulence
Dry mouth

🚨 Serious Side Effects

Clostridium difficile-associated diarrhea
Bone fracture (hip, wrist, spine)
Hypomagnesemia
Acute interstitial nephritis
Cutaneous lupus erythematosus
Vitamin B12 deficiency (long-term)

⚠️ Rare Side Effects

Hepatic encephalopathy
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Agranulocytosis
Pancreatitis
Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Clopidogrel	Major	Reduced clopidogrel activation and antiplatelet effect
Methotrexate	Major	Increased methotrexate levels and toxicity
Rilpivirine	Major	Decreased rilpivirine absorption and efficacy
Atazanavir	Major	Decreased atazanavir absorption
Warfarin	Moderate	Increased INR and bleeding risk
Cilostazol	Moderate	Increased cilostazol levels
Diazepam	Moderate	Increased diazepam levels
Phenytoin	Moderate	Increased phenytoin levels
Citalopram	Moderate	Increased citalopram levels
Ketoconazole	Moderate	Decreased ketoconazole absorption
Iron salts	Moderate	Decreased iron absorption
Digoxin	Moderate	Increased digoxin levels
Sucralfate	Minor	Decreased esomeprazole absorption
Ampicillin	Minor	Decreased ampicillin absorption

🚨 Major Interactions

Clopidogrel
Methotrexate
Rilpivirine
Atazanavir
Nelfinavir
Saquinavir
Erlotinib
Dasatinib
Nilotinib
Mycophenolate mofetil

⚡ Moderate Interactions

Warfarin
Cilostazol
Diazepam
Phenytoin
Citalopram
Escitalopram
Ketoconazole
Itraconazole
Iron salts
Digoxin
Tacrolimus
Cyclosporine

ℹ️ Minor Interactions

Sucralfate
Ampicillin
Bisphosphonates
Tyrosine kinase inhibitors

🍽️ Food Interactions

Food may delay absorption; best taken on an empty stomach at least 1 hour before a meal.

🍷 Alcohol Interaction

No direct interaction; alcohol may exacerbate gastric irritation.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to esomeprazole or substituted benzimidazoles; concomitant use with rilpivirine-containing products.

📊 Monitoring Parameters

Symptoms of acid reflux, endoscopic healing, serum magnesium levels (with prolonged use), bone mineral density (long-term), liver function tests.

🤱 Lactation Safety

Excreted in breast milk; caution advised; avoid if possible.

💊 Overdose Management

Supportive care; no specific antidote; hemodialysis not effective.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

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🔄 Substitutes for ceso 20mg tablet

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Alternative brands with exact same active ingredient (Esomeprazole (20mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.