centwin 10mg injection - Dicyclomine (10mg) medicine

Dicyclomine 10mg Injection: Complete Medicine Guide

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🏭 Centaur Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Established for gastrointestinal spasms.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Rapid or irregular heartbeat
  • Difficulty breathing or swallowing
  • Swelling of face, lips, or throat
  • Severe abdominal pain
  • Inability to urinate
  • Confusion or hallucinations
  • High fever with dry skin

If experiencing severe symptoms, call emergency services immediately.

What is centwin 10mg injection used for?

Dicyclomine injection is an antispasmodic medicine used to relieve abdominal cramps and spasms in conditions like irritable bowel syndrome. It works by relaxing the smooth muscles of the gut.

  • Generic Name: Dicyclomine
  • Manufacturer: Centaur Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 centwin 10mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा पेट की ऐंठन और दर्द को कम करने के लिए इस्तेमाल की जाती है। यह इरिटेबल बोवेल सिंड्रोम, पित्त की नली की ऐंठन और गुर्दे की ऐंठन में राहत देती है। यह मांसपेशियों को आराम देकर काम करती है। यह इंजेक्शन के रूप में डॉक्टर द्वारा दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, धुंधली दृष्टि, चक्कर आना, नींद आना, जी मिचलाना और कब्ज शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन तेज़ धड़कन, पेशाब में कठिनाई, और एलर्जी प्रतिक्रिया हो सकती है।

सुरक्षा सलाह: यह दवा केवल डॉक्टर द्वारा दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। ग्लूकोमा, पेशाब की समस्या, या हृदय रोग हो तो डॉक्टर को बताएं। दवा लेने के बाद गाड़ी न चलाएं। शरुआब न पिएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 centwin 10mg injection Uses & Benefits

[{"condition":"Irritable bowel syndrome (IBS)","description":"Relieves abdominal cramps and spasms associated with IBS.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Helps relax smooth muscle spasms in the biliary tract.","evidence":"Established"},{"condition":"Renal colic","description":"Used as an adjunct to relieve spasms in the urinary tract.","evidence":"Limited"},{"condition":"Gastrointestinal spasm","description":"Provides relief from spasms in various gastrointestinal conditions.","evidence":"Established"}]

Off-label uses: [{"condition":"Infant colic","description":"Sometimes prescribed off-label, but not recommended due to safety concerns.","evidence":"Limited and controversial"}]

Primary treatment for: Irritable bowel syndrome

Also treats: Biliary colic, Renal colic, Gastrointestinal spasm

📋 Drug Information

Generic Name(s)Dicyclomine
Brand NameBencolic 20mg Tablet
ManufacturerCentaur Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassAnticholinergic- antispasmodic
Route of AdministrationIntramuscular or intravenous injection
StorageStore at room temperature (15-30°C). Protect from light.
Shelf LifeNot established from the available information.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only in a clinical setting where resuscitation equipment is available.
2
Monitor heart rate and blood pressure before and after administration.
3
Ask patients about glaucoma, urinary retention, or myasthenia gravis before giving this medicine.
4
Warn patients about drowsiness and advise them not to drive immediately after receiving the injection.
5
Use the lowest effective dose for the shortest duration necessary.
6
In elderly patients, start with a lower dose and monitor for confusion or urinary retention.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Abdominal cramps
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Headache
This medicine is not for general headaches.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot established from the available information for the injection form.
DistributionNot established from the available information for the injection form.
Protein BindingNot established from the available information.
MetabolismNot established from the available information for the injection form.
Half-LifeNot established from the available information for the injection form.
ExcretionNot established from the available information for the injection form.
BioavailabilityNot established from the available information for the injection form.
Onset of ActionOnset of action is typically within 15 to 30 minutes after intramuscular injection.
Peak Plasma TimeNot established from the available information for the injection form.
Duration of ActionThe effect may last for 4 to 6 hours.

How It Works

Dicyclomine is a tertiary amine antimuscarinic agent that blocks acetylcholine at muscarinic receptors on smooth muscle cells. This action reduces excessive contractions in the gastrointestinal tract, relieving spasms and associated pain. It also has a direct relaxant effect on smooth muscle, which contributes to its antispasmodic activity.

Mechanism Steps

1
Binding to muscarinic receptors: Dicyclomine binds competitively to muscarinic acetylcholine receptors on smooth muscle cells.
2
Inhibition of acetylcholine action: By blocking acetylcholine, it prevents the normal stimulation of smooth muscle contractions.
3
Smooth muscle relaxation: The blockade leads to relaxation of the smooth muscle, reducing spasms and pain.
4
Direct relaxant effect: Dicyclomine also has a direct relaxant effect on smooth muscle, independent of its anticholinergic action.

💡 How to Take centwin 10mg injection

Strength: Injection: 10 mg per vial

1This medicine is given by a healthcare professional.
2It is administered as an intramuscular or intravenous injection.
3Do not self-administer.
4Follow your doctor's instructions for monitoring.

Dosage Information

Adult DosageThe usual adult dose is 10 to 20 mg intramuscularly or intravenously every 4 to 6 hours as needed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to anticholinergic effects. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician.
Renal ImpairmentNot established from the available information. Use with caution in renal impairment.
Hepatic ImpairmentNot established from the available information. Use with caution in hepatic impairment.
Maximum Daily DoseNot established from the available information. Dose must be individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Any food
No specific food interactions known
This medicine is given as an injection in a clinical setting.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of centwin 10mg injection

✅ Common Side Effects

Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult doctor if persistent.
Blurred vision (Common (5-10%))
Avoid driving until vision clears. Consult doctor if persistent.
Dizziness (Common (5-10%))
Lie down and rest. Avoid sudden movements.
Drowsiness (Common (5-10%))
Avoid operating machinery. Consult doctor if excessive.
Nausea (Common (5-10%))
Take with food if possible. Consult doctor if persistent.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if persistent.

🚨 Serious Side Effects

Fast heartbeat (Rare (<0.1%))
Seek immediate medical attention.
Difficulty urinating (Rare (<0.1%))
Seek immediate medical attention.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if swelling of face, lips, or throat occurs.
Confusion (Rare (<0.1%))
Seek immediate medical attention.

⚠️ Rare Side Effects

Hallucinations
Seek immediate medical attention.
Psychosis
Seek immediate medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Anticholinergic drugs Major
MAO inhibitors Major
Tricyclic antidepressants Moderate
Amantadine Moderate
Antacids Minor

🚨 Major Interactions

  • Anticholinergic drugs (e.g., atropine, antihistamines)
  • MAO inhibitors

⚡ Moderate Interactions

  • Tricyclic antidepressants
  • Amantadine

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness. Avoid alcohol while receiving this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Glaucoma","Urinary retention","Myasthenia gravis","Severe ulcerative colitis","Known hypersensitivity to dicyclomine"]

⚠️ Warnings & Precautions

["Use with caution in elderly patients.","May cause drowsiness; avoid driving.","Use with caution in patients with heart disease.","Use with caution in patients with kidney or liver disease.","May worsen gastroesophageal reflux."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe anticholinergic symptoms such as rapid heartbeat, fever, confusion, and hallucinations. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

This medicine is usually given as a single dose in a clinical setting. If you miss a scheduled dose, contact your healthcare provider for instructions.

Additional Safety Advice

General Safety

This medicine should only be given by a healthcare professional. Do not self-administer. Inform your doctor if you have glaucoma, prostate problems, urinary retention, or heart disease. Avoid driving or operating machinery until you know how this medicine affects you. Do not drink alcohol while receiving this medicine. Tell your doctor about all other medicines you are taking, especially antihistamines, antidepressants, and pain relievers. Keep all follow-up appointments.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to anticholinergic effects such as confusion, urinary retention, and constipation. Use with caution and lower doses may be appropriate.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. It should be used only if clearly needed.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may affect bowel motility and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine, as it may cause dry mouth and affect dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce abdominal pressure.
🥗
Eat small, frequent meals to avoid overloading the digestive system.
😴
Avoid trigger foods that worsen your symptoms.
💧
Practice stress-reduction techniques like yoga or meditation.
🧘
Stay physically active with low-impact exercises.
🌞
Get adequate sleep to help your body recover.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after receiving this injection due to possible dizziness and drowsiness. Light activity is fine once you feel alert.

🥗 Diet Recommendations

Eat a high-fiber diet to prevent constipation.
Avoid spicy and fatty foods that can trigger spasms.
Stay well hydrated.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and blurred vision, affecting your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It is usually given in a clinical setting, so work impact is minimal for occasional use.

🛑 When to Stop This Medicine

Stop using this medicine only on your doctor's advice. If you experience severe side effects, seek immediate medical attention. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of dicyclomine injection is not recommended. Prolonged use may lead to tolerance and increased risk of anticholinergic side effects. Regular monitoring by a doctor is advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary changes

Avoiding trigger foods can help manage IBS symptoms.

Evidence: Well-established
Stress management

Yoga, meditation, and counseling can reduce stress-related spasms.

Evidence: Established
Probiotics

May help balance gut bacteria and reduce symptoms.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light. If traveling across time zones, consult your doctor for dose adjustments. Keep it in your carry-on luggage. Check customs regulations for injectable medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with severe abdominal cramps due to irritable bowel syndrome
She received dicyclomine injection in the emergency department. Within 20 minutes, her pain significantly decreased. She experienced mild dry mouth but was otherwise comfortable. She was later switched to oral therapy.
💡 Lesson: Dicyclomine injection provides rapid relief from severe abdominal spasms, but it is for short-term use under medical supervision.
👤 A 60-year-old man with biliary colic
He was given dicyclomine injection for severe right upper abdominal pain. His pain improved, but he developed urinary retention requiring catheterization. He had a history of benign prostatic hyperplasia.
💡 Lesson: Elderly men with prostate enlargement are at higher risk of urinary retention with anticholinergic medicines like dicyclomine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: It usually starts working within 15 to 30 minutes after injection.

Q: Can I take this medicine at home?

A: No, it must be given by a healthcare professional in a clinical setting.

Q: Is it safe in pregnancy?

A: Consult your doctor. It should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for centwin 10mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Dicyclomine injection is a painkiller for all types of pain.
    Fact: It is specifically for smooth muscle spasms in the gut and not for general pain.
  • Myth: Dicyclomine injection can be self-administered.
    Fact: It must be given by a healthcare professional.

🔄 Alternative Options

Generic Alternatives

  • Dicyclomine injection

Brand Alternatives

  • Cyclopam 10mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Dicyclomine","class":"Anticholinergic antispasmodic","route":"Injection","common_use":"IBS, GI spasms"},{"medicine":"Hyoscine butylbromide","class":"Antispasmodic","route":"Oral/Injection","common_use":"Abdominal cramps"}]

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