celetoin 100 tablet - Phenytoin (100mg) medicine

celetoin 100 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Intas Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is celetoin 100 tablet used for?

Abolin 100mg Tablet (Phenytoin) is used to treat NEURO CNS. It contains Phenytoin (100mg), which Stabilizes neuronal membranes by blocking voltage-gated sodium channels, reducin. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Phenytoin
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š celetoin 100 tablet Uses & Benefits

Generalized tonic-clonic seizures, partial seizures, prevention of seizures during neurosurgery.

Off-label uses: Trigeminal neuralgia, bipolar disorder, neuropathic pain.

๐Ÿ“‹ Drug Information

Generic Name(s)Phenytoin
Brand NameAbolin 100mg Tablet
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassSodium channel modulators (AED)
Route of AdministrationOral, intravenous.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSlowly absorbed from the gastrointestinal tract; rate varies by formulation.
DistributionWidely distributed; crosses blood-brain barrier and placenta.
Protein Binding90-95% bound to plasma albumin.
MetabolismHepatic via CYP2C9 and CYP2C19; saturable metabolism.
Half-Life22 hours (range 7-42 hours) depending on dose and metabolism.
ExcretionPrimarily renal as inactive metabolites; less than 5% unchanged.
BioavailabilityApproximately 90% for oral formulation.
Onset of Action2-4 hours for oral; IV immediate.
Peak Plasma Time4-12 hours after oral dose.
Duration of Action24 hours.

How It Works

Stabilizes neuronal membranes by blocking voltage-gated sodium channels, reducing repetitive firing.

Mechanism Steps

1Binds to voltage-gated sodium channels in the inactive state.
2Prolongs the inactivation phase of sodium channels.
3Reduces repetitive neuronal firing.

๐Ÿ’ก How to Take celetoin 100 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of celetoin 100 tablet

โœ… Common Side Effects

  • Nystagmus
  • Ataxia
  • Drowsiness
  • Dizziness
  • Gingival hyperplasia
  • Hirsutism
  • Nausea
  • Vomiting

๐Ÿšจ Serious Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Hepatotoxicity
  • Blood dyscrasias
  • Lupus-like syndrome
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Peripheral neuropathy
  • Osteomalacia
  • Lymphadenopathy
  • Pseudolymphoma
  • Cerebellar atrophy

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk due to altered metabolism.
Carbamazepine Major Decreased phenytoin levels; increased carbamazepine toxicity.
Phenobarbital Major Decreased phenytoin levels; increased phenobarbital levels.
Valproic acid Major Increased phenytoin levels; decreased valproate levels.
Rifampin Major Decreased phenytoin levels.
Cimetidine Major Increased phenytoin levels.
Fluconazole Major Increased phenytoin levels.
Amiodarone Major Increased phenytoin levels.

๐Ÿšจ Major Interactions

  • Warfarin
  • Carbamazepine
  • Phenobarbital
  • Valproic acid
  • Rifampin
  • Cimetidine
  • Fluconazole
  • Amiodarone

โšก Moderate Interactions

  • Oral contraceptives
  • Corticosteroids
  • Doxycycline
  • Theophylline
  • Cyclosporine
  • Furosemide

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Aspirin
  • Ibuprofen
  • Antacids

๐Ÿฝ๏ธ Food Interactions

Enteral feeding may reduce absorption; avoid high-fat meals.

๐Ÿท Alcohol Interaction

Chronic alcohol use may decrease phenytoin levels; acute intoxication may increase levels.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to phenytoin or hydantoins; sinus bradycardia, sinoatrial block, second- and third-degree AV block, Adams-Stokes syndrome.

๐Ÿ“Š Monitoring Parameters

Serum phenytoin levels (therapeutic 10-20 mcg/mL), CBC, liver function, renal function, signs of toxicity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; activated charcoal if recent ingestion; hemodialysis ineffective.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for celetoin 100 tablet

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Alternative brands with exact same active ingredient (Phenytoin (100mg)):

Medical Note: Always consult your doctor before switching medications.

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