Adilip 135 Tablet DR (Choline Fenofibrate 135 mg): Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes, dark urine, or severe tiredness
- Severe upper abdominal pain, especially after fatty meals
- Unexplained muscle pain, weakness, or dark brown urine
- Unusual bruising or bleeding
- Sudden swelling of the face, lips, or throat, or difficulty breathing
- Severe, persistent stomach pain with nausea and vomiting
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is adilip 135 tablet dr used for?
This medicine is a prescription oral tablet containing choline fenofibrate 135 mg. It is a fibrate used to lower very high triglycerides and improve cholesterol levels in adults when diet and exercise are not enough. It works by activating PPAR-alpha, which helps the body break down and clear triglyceride-rich fats from the blood. It is taken once daily with food and requires regular monitoring of liver and kidney function.
- Generic Name: Choline fenofibrate
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 adilip 135 tablet dr के बारे में (Hindi Summary)
उपयोग: यह दवा कोलीन फेनोफाइब्रेट 135 मिलीग्राम की एक प्रिस्क्रिप्शन टैबलेट है, जिसे मुख्य रूप से खून में ट्राइग्लिसराइड की बहुत अधिक मात्रा को कम करने के लिए इस्तेमाल किया जाता है। यह फाइब्रेट वर्ग की दवा है और इसे आहार तथा व्यायाम के साथ लेने पर सबसे अच्छा असर दिखाती है। यह दवा शरीर में PPAR-alfa नामक रिसेप्टर को सक्रिय करके ट्राइग्लिसराइड को तोड़ने और साफ करने में मदद करती है, साथ ही अच्छे कोलेस्ट्रॉल यानी HDL को थोड़ा बढ़ाती है। डॉक्टर इसे अक्सर उन लोगों को देते हैं जिनका ट्राइग्लिसराइड बहुत ज्यादा हो और जिनमें पैंक्रियाटाइटिस का खतरा हो। यह दवा लीवर की बीमारी, पित्ताशय की बीमारी, गंभीर किडनी की समस्या या इस दवा से एलर्जी वाले लोगों के लिए नहीं है। इसे डॉक्टर की सलाह के बिना शुरू या बंद न करें और नियमित रूप से लीवर, किडनी तथा लिपिड की जांच कराते रहें।
साइड इफेक्ट्स: इस दवा को ज्यादातर लोग अच्छी तरह सहन करते हैं, लेकिन कुछ लोगों में हल्के से मध्यम दुष्प्रभाव हो सकते हैं। आम दुष्प्रभावों में सिरदर्द, जी मिचलाना, पेट में असहजता, दस्त और मांसपेशियों में हल्का दर्द शामिल हैं। ये अक्सर कुछ समय में ठीक हो जाते हैं। कभी-कभी लीवर की जांच में बदलाव, पित्त की पथरी, पैंक्रियाटाइटिस, मांसपेशियों की गंभीर समस्या या एलर्जी जैसी गंभीर समस्याएं हो सकती हैं। अगर आंख या त्वचा पीली पड़ने लगे, पेशाब गहरा हो जाए, पेट में तेज दर्द हो, मांसपेशियों में असहनीय दर्द या कमजोरी हो, या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार भोजन के साथ, जिससे अवशोषण बेहतर होता है और पेट की तकलीफ कम होती है। टैबलेट को पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं, जब तक डॉक्टर या फार्मासिस्ट ऐसा करने को न कहें। दवा की खुराक खुद से कम या ज्यादा न करें और न ही बंद करें। लीवर, किडनी और लिपिड की जांच के लिए समय-समय पर डॉक्टर के पास जाते रहें। अपने डॉक्टर को बताएं कि आप कौन-कौन सी दवाएं, सप्लीमेंट या हर्बल उत्पाद ले रहे हैं, खासकर खून पतला करने वाली दवाएं और स्टैटिन। इस दवा के साथ शराब न पिएं क्योंकि इससे लीवर और ट्राइग्लिसराइड की समस्या बढ़ सकती है। गर्भावस्था, गर्भधारण की योजना या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को सूखी, ठंडी जगह पर, धूप से दूर, बच्चों की पहुंच से बाहर रखें।
💊 adilip 135 tablet dr Uses & Benefits
[{"condition":"Severe hypertriglyceridemia","description":"This medicine is used to lower very high triglyceride levels in adults when diet and exercise alone are not enough, helping to reduce the risk of pancreatitis.","evidence":"Well-established"},{"condition":"Mixed dyslipidemia","description":"This medicine may be used to improve triglyceride and HDL cholesterol levels in people with a combination of high triglycerides and abnormal cholesterol levels.","evidence":"Well-established"},{"condition":"Primary hypercholesterolemia","description":"This medicine may be prescribed as an adjunct to diet in some patients with high LDL cholesterol, often when statins are not tolerated or are insufficient.","evidence":"Moderate"},{"condition":"Diabetic dyslipidemia","description":"This medicine can help manage abnormal lipid levels in people with type 2 diabetes, but it is used alongside standard diabetes and lipid care.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Non-alcoholic fatty liver disease","description":"Sometimes studied or used off-label to improve liver enzymes and lipid profile in selected patients with fatty liver, but it is not a standard approved treatment.","evidence":"Limited"},{"condition":"Reducing cardiovascular risk in selected patients","description":"Fibrates have been studied for cardiovascular risk reduction, but benefits are not consistent across all patient groups and this is not a routine off-label use.","evidence":"Limited"}]
Primary treatment for: Hypertriglyceridemia
Also treats: Mixed dyslipidemia, Diabetic dyslipidemia, Primary hypercholesterolemia
📋 Drug Information
| Generic Name(s) | Choline fenofibrate |
| Brand Name | Adilip 135 Tablet DR |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | PPAR alpha agonists (Fibrate) |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C. Keep it in the original container, tightly closed, away from moisture, heat, and direct sunlight. Do not store it in the bathroom. Keep it out of reach of children and pets. |
| Shelf Life | The shelf life is usually 24 months from the date of manufacture, but always check the expiry date printed on the pack. Do not use the medicine after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains choline fenofibrate, which is converted in the body to fenofibric acid, the active form. Fenofibric acid activates peroxisome proliferator-activated receptor alpha, or PPAR-alpha, a nuclear receptor that controls the expression of genes involved in lipid metabolism. Activation of PPAR-alpha increases the activity of lipoprotein lipase and reduces apolipoprotein C-III, which together enhance the breakdown and clearance of triglyceride-rich particles such as VLDL. It also increases the production of apolipoprotein A-I and A-II, which can raise HDL cholesterol. In addition, this medicine can reduce the production of certain proteins involved in cholesterol and triglyceride assembly. The net effect is a significant reduction in blood triglycerides, a modest increase in HDL cholesterol, and variable effects on LDL cholesterol.
Mechanism Steps
💡 How to Take adilip 135 tablet dr
Strength: Choline fenofibrate 135 mg immediate-release tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one 135 mg tablet taken orally once daily, with or without food, although taking it with food improves absorption and reduces stomach upset. The dose may be adjusted by your doctor based on your triglyceride levels, kidney function, and other medicines you take. Some patients may need a different strength or frequency. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose on your own. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults can generally take the same adult dose, but they may be more sensitive to side effects such as muscle aches and liver enzyme changes. Kidney function often declines with age, so your doctor may check kidney function and adjust the dose if needed. Regular monitoring is important in people above 65 years of age. |
| Renal Impairment | In people with mild to moderate kidney impairment, the usual dose may be used, but closer monitoring is advised. In severe kidney impairment, this medicine is generally not recommended or may require a reduced dose. Dose must be individualized by a qualified clinician based on kidney function tests. |
| Hepatic Impairment | This medicine is not recommended in people with severe liver disease or unexplained persistent liver enzyme elevation. In mild to moderate liver impairment, it should be used with caution and only under close medical supervision. Dose must be individualized by a qualified clinician based on liver function tests. |
| Maximum Daily Dose | The maximum recommended daily dose is 135 mg of choline fenofibrate, equivalent to 135 mg of fenofibric acid, taken once daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of adilip 135 tablet dr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Atorvastatin | Major | |
| Rosuvastatin | Major | |
| Simvastatin | Major | |
| Cholestyramine | Major | |
| Cyclosporine | Major | |
| Colchicine | Moderate | |
| Niacin | Moderate | |
| Sulfonylureas | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin and other vitamin K antagonists
- Statins such as atorvastatin, rosuvastatin, and simvastatin
- Bile acid sequestrants such as cholestyramine
- Cyclosporine
⚡ Moderate Interactions
- Oral diabetes medicines such as sulfonylureas
- Colchicine
- High-dose niacin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can raise triglyceride levels, reduce the effectiveness of lipid-lowering therapy, and increase the risk of liver problems. If you drink alcohol regularly, discuss this with your doctor before starting or continuing this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to choline fenofibrate, fenofibrate, or any ingredient in this medicine","Severe liver disease or unexplained persistent elevation of liver enzymes","Known gallbladder disease or gallstones","Severe kidney impairment or end-stage kidney disease","Breastfeeding","Use in children, as safety and effectiveness are not established"]
⚠️ Warnings & Precautions
["This medicine can cause liver injury. Report yellowing of the skin or eyes, dark urine, or severe tiredness immediately.","This medicine can increase the risk of gallstones. Report severe upper abdominal pain, especially after fatty meals.","This medicine can rarely cause severe muscle injury. Report unexplained muscle pain, weakness, or dark urine, especially if you also take a statin.","This medicine can increase the effect of blood thinners such as warfarin. Regular INR monitoring is needed if both are used.","Avoid alcohol while taking this medicine because it can worsen liver and triglyceride problems.","This medicine is not recommended during pregnancy or breastfeeding unless clearly needed and advised by your doctor.","Do not use this medicine in children, as safety and effectiveness have not been established.","Tell your doctor about all other medicines, supplements, and herbal products you take before starting this medicine."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk in significant amounts. Because of the potential for serious side effects in a breastfed baby, breastfeeding is not recommended while taking this medicine unless your doctor advises otherwise. Discuss infant feeding options with your doctor.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and may include monitoring of liver, kidney, and muscle function. Do not try to vomit unless instructed by a medical professional. Keep the medicine container with you so that medical staff can see exactly what was taken.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually once daily with food to improve absorption and reduce stomach upset. Do not crush, chew, or split the tablet unless your doctor or pharmacist says it is acceptable. Swallow it whole with a glass of water. Do not start or stop this medicine on your own, and do not change the dose without medical advice. Keep all follow-up appointments so your doctor can monitor liver enzymes, kidney function, and lipid levels. Tell your doctor about all other medicines, supplements, and herbal products you take, especially blood thinners, statins, and diabetes medicines. Avoid alcohol while taking this medicine because it can worsen liver and triglyceride problems. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Store the tablets at room temperature, away from moisture and direct sunlight, and keep them out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults may be more sensitive to the side effects of this medicine, especially muscle aches and liver enzyme changes. Kidney function often declines with age, so your doctor may check kidney function and adjust the dose if needed. Regular monitoring of liver and kidney function and lipid levels is important. Falls and muscle weakness should be reported promptly.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before continuing this medicine. It is generally not recommended during pregnancy unless clearly needed. Your doctor may switch you to a safer alternative or adjust your treatment plan. Use effective contraception while taking this medicine unless your doctor advises otherwise.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily, especially if you are also taking blood thinners or have liver or kidney problems. Do not stop it on your own; follow your doctor's instructions about when to pause and when to restart.
🦷 Dental Procedures
Tell your dentist that you are taking this medicine, especially if you are also on blood thinners, as there may be a higher risk of bleeding during dental procedures. Your dentist may take extra precautions. Do not stop this medicine before dental work unless your doctor advises it.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged while taking this medicine, but if you experience unusual muscle pain, weakness, or cramping during or after exercise, stop and consult your doctor. This is especially important if you also take a statin, as the risk of muscle injury is higher. Stay well hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to work or drive. However, if you feel dizzy, tired, or unwell after taking it, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal daily activities while taking this medicine, as long as they follow their doctor's advice and attend regular check-ups.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor may decide to stop or change it if your lipid levels are well controlled, if you develop serious side effects, or if you become pregnant. If you experience severe muscle pain, yellowing of the skin or eyes, severe stomach pain, or signs of an allergic reaction, stop the medicine and seek medical help immediately. Always discuss any decision to stop with your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored properly, but it can increase the risk of gallstones, liver enzyme elevation, and muscle problems. Regular blood tests for liver and kidney function and lipid levels are recommended. Some patients may need dose adjustments over time. If you develop new symptoms such as muscle pain, yellowing of the eyes, or severe stomach pain, contact your doctor promptly. Do not stop the medicine on your own, as triglycerides may rise again.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A diet low in refined sugars, saturated fats, and alcohol can significantly lower triglycerides.
Evidence: Well-establishedAerobic exercise helps lower triglycerides and improve HDL cholesterol.
Evidence: Well-establishedLosing excess weight can reduce triglyceride levels and improve overall metabolic health.
Evidence: Well-establishedPrescription omega-3 products may help lower triglycerides in some patients, but they are not a substitute for this medicine unless advised by a doctor.
Evidence: ModerateStatins mainly lower LDL cholesterol and may be used with or instead of fibrates depending on the lipid profile.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. You can receive vaccinations as recommended by your doctor. If you are unwell or have a fever, it is usually better to postpone vaccination until you recover. Always inform the healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the label intact
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's note if you are travelling internationally, especially for longer trips. Keep the tablets in your hand luggage rather than checked baggage to avoid loss or temperature extremes. Store them at room temperature, away from direct sunlight and moisture. If you are crossing time zones, take your once-daily dose at approximately the same time each day according to your usual routine, and ask your doctor if any adjustment is needed. Check local customs rules for carrying prescription medicines before you travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few days, but the full effect on triglycerides and cholesterol is usually seen after 4 to 8 weeks of regular use. Your doctor will check your lipid profile to see how well it is working.
A: Yes, taking this medicine with food is recommended because it improves absorption and reduces stomach upset.
A: No, do not stop this medicine without consulting your doctor. Triglycerides can rise again if the medicine is stopped suddenly.
A: This medicine can raise liver enzymes and rarely cause liver injury. Your doctor will check liver function tests before and during treatment. Report yellowing of the skin or eyes, dark urine, or severe tiredness immediately.
A: Alcohol should be avoided while taking this medicine because it can raise triglycerides and increase the risk of liver problems.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be taken without any blood tests.
Fact: Regular blood tests for liver, kidney, and lipid levels are important while taking this medicine. - Myth: This medicine is a substitute for a healthy diet and exercise.
Fact: This medicine works best along with a healthy diet, regular exercise, and weight management. - Myth: This medicine can be stopped as soon as triglycerides improve.
Fact: Do not stop this medicine without consulting your doctor, as triglycerides may rise again. - Myth: This medicine is safe to combine with any other medicine.
Fact: This medicine can interact with blood thinners, statins, and other medicines. Always tell your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Choline fenofibrate 135 mg tablet
- Fenofibrate 145 mg tablet
Brand Alternatives
- Adilip 135 Tablet DR