caxin 0.25mg tablet - Digoxin (0.25mg) medicine

caxin 0.25mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ East West Pharma ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is caxin 0.25mg tablet used for?

Cardisip Syrup (Digoxin) is used to treat CARDIAC. It contains Digoxin (0.25mg), which Inhibits Na+/K+ ATPase, increasing intracellular sodium, which reduces calcium e. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Digoxin
  • Manufacturer: East West Pharma
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š caxin 0.25mg tablet Uses & Benefits

Heart failure (NYHA II-IV), Atrial fibrillation (rate control), Atrial flutter

Off-label uses: Supraventricular tachycardia, Fetal tachycardia (maternal administration)

๐Ÿ“‹ Drug Information

Generic Name(s)Digoxin
Brand NameCardisip Syrup
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCardiac glycosides
Route of AdministrationOral (syrup); IV (in hospital settings).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed from the gastrointestinal tract; oral bioavailability is 60-80%.
DistributionWidely distributed; crosses placenta; appears in breast milk; Vd 5-7 L/kg.
Protein Binding20-30%
MetabolismHepatic (minor) via reduction, hydrolysis, and conjugation; some gut metabolism.
Half-Life36-48 hours (normal renal function); prolonged in renal impairment.
ExcretionRenal (50-70% unchanged); some biliary excretion.
Bioavailability60-80% (oral); 100% (IV).
Onset of ActionOral: 0.5-2 hours; IV: 5-30 minutes.
Peak Plasma TimeOral: 2-6 hours; IV: 1-4 hours.
Duration of Action3-4 days (after steady state).

How It Works

Inhibits Na+/K+ ATPase, increasing intracellular sodium, which reduces calcium efflux via Na+/Ca2+ exchanger, leading to increased intracellular calcium and positive inotropy.

Mechanism Steps

1Binds to and inhibits Na+/K+ ATPase on cardiac myocytes.
2Increases intracellular sodium concentration.
3Reduces activity of Na+/Ca2+ exchanger (NCX), decreasing calcium efflux.

๐Ÿ’ก How to Take caxin 0.25mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of caxin 0.25mg tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Anorexia
  • Headache
  • Dizziness
  • Blurred vision
  • Yellow-green halos

๐Ÿšจ Serious Side Effects

  • Arrhythmias (ventricular tachycardia, AV block, atrial tachycardia with block)
  • Severe bradycardia
  • Heart block
  • Cardiac arrest

โš ๏ธ Rare Side Effects

  • Gynecomastia
  • Thrombocytopenia
  • Allergic reactions
  • Confusion
  • Depression

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Amiodarone Major Increased digoxin levels; risk of toxicity.
Verapamil Major Increased digoxin levels; bradycardia.
Quinidine Major Decreased digoxin clearance; toxicity risk.
Spironolactone Major Increased digoxin levels; may interfere with digoxin assay.
Clarithromycin Major Increased digoxin absorption; toxicity.
Itraconazole Major Increased digoxin levels.
Cyclosporine Major Increased digoxin levels.
Propafenone Major Increased digoxin levels.

๐Ÿšจ Major Interactions

  • Amiodarone
  • Verapamil
  • Quinidine
  • Spironolactone
  • Clarithromycin
  • Itraconazole
  • Cyclosporine
  • Propafenone

โšก Moderate Interactions

  • Alprazolam
  • Atorvastatin
  • Carvedilol
  • Diltiazem
  • Flecainide
  • Indomethacin
  • Nifedipine
  • Omeprazole
  • Tetracycline

โ„น๏ธ Minor Interactions

  • Acarbose
  • Aluminum hydroxide
  • Cholestyramine
  • Metoclopramide
  • Sulfasalazine

๐Ÿฝ๏ธ Food Interactions

High-fiber foods may reduce absorption; avoid taking with bran or pectin.

๐Ÿท Alcohol Interaction

No significant interaction; moderate use may be acceptable.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, Ventricular fibrillation, AV block (2nd/3rd degree), Wolff-Parkinson-White syndrome with atrial fibrillation, Hypertrophic obstructive cardiomyopathy, Hypokalemia, Hypercalcemia

๐Ÿ“Š Monitoring Parameters

Serum digoxin levels (therapeutic 0.5-2 ng/mL), ECG, renal function, electrolytes (K+, Mg2+, Ca2+), heart rate.

๐Ÿคฑ Lactation Safety

Limited data; use with caution; monitor infant for toxicity.

๐Ÿ’Š Overdose Management

Activated charcoal, digoxin-specific Fab antibody fragments (Digibind), correction of electrolyte imbalances, supportive care for arrhythmias.

โฐ Missed Dose

If within 12 hours, take missed dose; if >12 hours, skip and resume next scheduled dose; do not double.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for caxin 0.25mg tablet

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Alternative brands with exact same active ingredient (Digoxin (0.25mg)):

Medical Note: Always consult your doctor before switching medications.

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