allerde m tablet - Uses, Price, Side Effects & Substitutes
What is allerde m tablet used for?
Alorti-M Tablet (Desloratadine + Montelukast) is used to treat RESPIRATORY. It contains Desloratadine (5mg) + Montelukast (10mg), which Desloratadine: Selective peripheral H1-receptor antagonist; Montelukast: Selecti. Always consult your doctor before use. Take as prescribed.
- Generic Name: Desloratadine + Montelukast
- Manufacturer: East West Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ allerde m tablet Uses & Benefits
Seasonal allergic rhinitis, perennial allergic rhinitis, asthma prophylaxis.
Off-label uses: Urticaria, chronic idiopathic urticaria (desloratadine); exercise-induced bronchoconstriction (montelukast).
๐ Drug Information
| Generic Name(s) | Desloratadine + Montelukast |
| Brand Name | Alorti-M Tablet |
| Manufacturer | East West Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Leukotriene Receptor Antagonist |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Desloratadine: Selective peripheral H1-receptor antagonist; Montelukast: Selective leukotriene receptor antagonist (CysLT1).
Mechanism Steps
๐ก How to Take allerde m tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of allerde m tablet
โ Common Side Effects
- Headache
- Somnolence
- Fatigue
- Dry mouth
- Pharyngitis
๐จ Serious Side Effects
- Hypersensitivity reactions
- Angioedema
- Severe skin reactions
- Behavioral changes (montelukast)
โ ๏ธ Rare Side Effects
- Seizures
- Tachycardia
- Hepatitis
- Eosinophilic granulomatosis with polyangiitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | Increased desloratadine levels |
| Fluconazole | Major | Increased montelukast levels |
| Phenobarbital | Major | Decreased montelukast efficacy |
| Rifampin | Major | Decreased montelukast levels |
| Gemfibrozil | Moderate | Increased montelukast levels |
| Erythromycin | Moderate | Increased montelukast levels |
| Cimetidine | Minor | Slight increase in desloratadine levels |
| Theophylline | Minor | No significant interaction |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP2C9 inhibitors (e.g., fluconazole)
- Phenobarbital
- Rifampin
โก Moderate Interactions
- Gemfibrozil
- Itraconazole
- Erythromycin
โน๏ธ Minor Interactions
- Cimetidine
- Theophylline
๐ฝ๏ธ Food Interactions
Montelukast: Food may decrease absorption; take on empty stomach.
๐ท Alcohol Interaction
May increase CNS depression; avoid alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe hepatic impairment.
๐ Monitoring Parameters
Liver function tests, renal function, psychiatric symptoms (montelukast).
๐คฑ Lactation Safety
Desloratadine: Excreted in breast milk; caution. Montelukast: Excreted in breast milk; caution.
๐ Overdose Management
Symptomatic and supportive treatment; no specific antidote.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose.