allerde m tablet - Desloratadine (5mg) + Montelukast (10mg) medicine

Alorti-M Tablet: Complete Guide to Uses, Side Effects, and Safety

No reviews yet
🏭 East West Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and asthma.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden swelling of face, lips, or throat
  • Difficulty breathing or severe wheezing
  • Chest pain or fast, irregular heartbeat
  • New or worsening depression, agitation, or suicidal thoughts
  • Yellowing of skin or eyes, dark urine, or severe abdominal pain
  • Severe skin rash with blisters or peeling
  • Persistent headache or vision changes

If experiencing severe symptoms, call emergency services immediately.

What is allerde m tablet used for?

This medicine is a combination of Desloratadine (an antihistamine) and Montelukast (a leukotriene receptor antagonist) used to treat allergic rhinitis and asthma. It relieves sneezing, runny nose, and airway inflammation. Take one tablet daily as prescribed.

  • Generic Name: Desloratadine + Montelukast
  • Manufacturer: East West Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allerde m tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी राइनाइटिस और अस्थमा के इलाज के लिए इस्तेमाल की जाती है। यह छींक, नाक बहना, खुजली और आंखों में पानी आना कम करती है। यह सांस की नली में सूजन को भी कम करती है। यह दवा तीव्र अस्थमा हमले के लिए नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मुंह सूखना, थकान और हल्की नींद आना शामिल हैं। कुछ लोगों को पेट दर्द, मतली या दस्त हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन मूड में बदलाव, अवसाद या सूजन हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कम या ज्यादा न करें। तीव्र अस्थमा हमले के लिए यह दवा नहीं है। शराब न पिएं क्योंकि इससे नींद और चक्कर आ सकते हैं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 allerde m tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and nasal congestion associated with seasonal and perennial allergies.","evidence":"Well-established"},{"condition":"Asthma","description":"Used as add-on controller therapy to reduce airway inflammation and prevent asthma symptoms.","evidence":"Well-established"},{"condition":"Exercise-induced bronchoconstriction","description":"May help prevent narrowing of airways triggered by physical activity.","evidence":"Moderate"},{"condition":"Chronic urticaria","description":"Helps reduce itching and hives in some patients with chronic spontaneous urticaria.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Atopic dermatitis","description":"Sometimes prescribed off-label to reduce itching associated with eczema.","evidence":"Limited"},{"condition":"Sleep-related breathing disorders","description":"Occasionally used off-label in children with mild sleep apnea and allergic rhinitis.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis and asthma

Also treats: Exercise-induced bronchoconstriction, Chronic urticaria

📋 Drug Information

Generic Name(s)Desloratadine + Montelukast
Brand NameAlorti-M Tablet
ManufacturerEast West Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Leukotriene Receptor Antagonist
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine in the evening for best control of morning allergy symptoms.
2
Do not use this medicine for acute asthma attacks; always keep a rescue inhaler available.
3
Monitor for mood changes, depression, or suicidal thoughts, especially in patients with a history of psychiatric illness.
4
Avoid alcohol and driving until you know how this medicine affects you.
5
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
6
Do not stop this medicine suddenly without consulting your doctor, especially if you have asthma.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing and runny nose
This medicine is commonly prescribed for allergic rhinitis.
Likely Use
✅
Wheezing and shortness of breath
Used as controller therapy for asthma, not for acute attacks.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Acute asthma attack
This medicine is not for immediate relief of acute asthma attacks.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDesloratadine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 3 hours. Montelukast is also rapidly absorbed, with peak plasma concentrations in 3 to 4 hours for the 10 mg tablet. Food does not significantly affect the absorption of either component.
DistributionBoth Desloratadine and Montelukast are highly protein-bound and distribute into tissues. Desloratadine has a volume of distribution of approximately 14 L/kg. Montelukast has a volume of distribution of approximately 8 to 11 L. Neither component crosses the blood-brain barrier significantly at therapeutic doses.
Protein BindingDesloratadine is approximately 87% bound to plasma proteins. Montelukast is more than 99% bound to plasma proteins.
MetabolismDesloratadine is extensively metabolized in the liver, primarily by CYP2C8 and CYP3A4, to active metabolite 3-hydroxydesloratadine. Montelukast is extensively metabolized in the liver, primarily by CYP2C8 and CYP3A4, and to a lesser extent by CYP2C9.
Half-LifeDesloratadine has an elimination half-life of approximately 27 hours. Montelukast has an elimination half-life of approximately 2.7 to 5.5 hours.
ExcretionDesloratadine and its metabolites are excreted in urine and feces. Montelukast is excreted primarily in bile and feces.
BioavailabilityDesloratadine oral bioavailability is approximately 70% to 80%. Montelukast oral bioavailability is approximately 64% for the 10 mg tablet.
Onset of ActionDesloratadine begins to relieve allergy symptoms within 1 hour. Montelukast may take several days to reach full therapeutic effect for asthma control.
Peak Plasma TimeDesloratadine peak plasma concentration occurs at approximately 3 hours. Montelukast peak plasma concentration occurs at approximately 3 to 4 hours.
Duration of ActionDesloratadine provides 24-hour symptom relief. Montelukast provides 24-hour asthma control with once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Desloratadine is a selective peripheral histamine H1-receptor antagonist that blocks histamine from binding to H1 receptors on blood vessels and nerve endings, reducing allergy symptoms such as sneezing, itching, and runny nose. Montelukast is a selective leukotriene receptor antagonist that blocks cysteinyl leukotrienes (LTC4, LTD4, LTE4) from binding to CysLT1 receptors in the airways, reducing bronchoconstriction, mucus secretion, and airway inflammation. Together, they address both histamine-mediated and leukotriene-mediated pathways of allergic inflammation.

Mechanism Steps

1
Histamine H1 receptor blockade: Desloratadine binds to peripheral H1 receptors, preventing histamine from triggering allergic symptoms such as sneezing, itching, and vasodilation.
2
Leukotriene receptor blockade: Montelukast binds to CysLT1 receptors in the airways, blocking leukotriene-mediated bronchoconstriction and inflammation.
3
Reduced airway inflammation: By blocking leukotrienes, Montelukast reduces eosinophil infiltration, mucus production, and airway edema.
4
Symptom relief: The combined action leads to reduced nasal and ocular allergy symptoms and improved asthma control.

💡 How to Take allerde m tablet

Strength: Tablet containing Desloratadine 5 mg and Montelukast 10 mg.

1Take one tablet orally once daily, preferably in the evening.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food.
4Do not crush, chew, or break the tablet unless advised by your doctor.
5Follow your doctor's instructions exactly.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once daily, preferably in the evening. However, the dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is not for acute asthma attacks.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageNo specific dose adjustment is required for elderly patients, but use with caution due to potential for increased sensitivity to side effects. Individualize dose by a qualified clinician.
Renal ImpairmentNo dose adjustment is required for mild to moderate renal impairment. Use with caution in severe renal impairment. Individualize dose by a qualified clinician.
Hepatic ImpairmentDose adjustment may be needed in patients with hepatic impairment. Consult a qualified clinician for individualized dosing.
Maximum Daily DoseOne tablet (Desloratadine 5 mg + Montelukast 10 mg) once daily.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take at the same time daily
Food does not significantly affect absorption.
Grapefruit
Avoid or limit
May increase Desloratadine levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allerde m tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Dry mouth (Common (3-5%))
Stay hydrated and chew sugar-free gum. Consult doctor if bothersome.
Fatigue (Common (3-5%))
Rest if needed. Avoid driving if you feel drowsy.
Nausea (Uncommon (1-3%))
Take with food to reduce stomach upset.
Diarrhea (Uncommon (1-3%))
Stay hydrated. Consult doctor if it persists.

🚨 Serious Side Effects

Neuropsychiatric events (agitation, aggression, depression, suicidal thoughts) (Rare (<0.1%))
Seek immediate medical attention if you notice mood or behavior changes.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency care if you experience swelling of face, lips, throat, or difficulty breathing.
Palpitations or fast heartbeat (Rare (<0.1%))
Contact your doctor immediately if you experience irregular or fast heartbeat.
Liver problems (elevated liver enzymes) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor.

⚠️ Rare Side Effects

Churg-Strauss syndrome
Seek medical attention if you develop fever, rash, and worsening respiratory symptoms.
Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency care if you develop painful rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Warfarin Major
Benzodiazepines Moderate
Rifampin Moderate
Phenobarbital Moderate
Antacids Minor
Grapefruit juice Minor
CNS depressants Moderate
Clarithromycin Major
Erythromycin Moderate

🚨 Major Interactions

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • Warfarin

⚡ Moderate Interactions

  • CNS depressants (e.g., benzodiazepines, opioids)
  • Phenobarbital, rifampin

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Desloratadine, Montelukast, or any component of the tablet","Children under 15 years of age unless prescribed by a pediatrician","Acute asthma attack (not for rescue therapy)"]

⚠️ Warnings & Precautions

["Neuropsychiatric events: Montelukast may cause mood changes, depression, or suicidal thoughts. Monitor closely.","Not for acute asthma attacks: Always keep a rescue inhaler available.","Drowsiness: May impair ability to drive or operate machinery.","Alcohol: Avoid alcohol as it may increase drowsiness.","Liver disease: Use with caution; dose adjustment may be needed.","Pregnancy and breastfeeding: Consult doctor before use.","Do not stop asthma controller therapy abruptly without medical advice."]

🤱 Lactation Safety

Desloratadine and Montelukast may pass into breast milk. Consult your doctor before breastfeeding while taking this medicine.

💊 Overdose Management

Seek emergency medical attention if you suspect an overdose. Symptoms may include drowsiness, thirst, dry mouth, headache, nausea, and tachycardia. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. This medicine is not for immediate relief of an acute asthma attack; always keep a rescue inhaler available if prescribed. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines you are taking, especially pain relievers, blood thinners, and certain antibiotics. Do not stop taking this medicine suddenly without consulting your doctor, especially if you have asthma. Keep this medicine out of reach of children. Store it at room temperature away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Use with caution and monitor for falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy while taking this medicine. The safety profile during pregnancy is not fully established.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Identify and avoid allergy triggers such as dust, pollen, and pet dander.
🥗
Use air purifiers and keep windows closed during high pollen seasons.
😴
Maintain a healthy weight to reduce asthma severity.
💧
Practice regular breathing exercises to improve lung function.
🧘
Get adequate sleep to support immune health.
🌞
Stay hydrated to keep airways moist.

🏋️ Exercise Considerations

Exercise is generally safe while taking this medicine. However, if you have exercise-induced bronchoconstriction, take your rescue inhaler as prescribed before exercise. Avoid strenuous activity if you feel dizzy or drowsy.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Eat plenty of fruits and vegetables rich in antioxidants.
Reduce intake of processed and high-sugar foods.
Stay well hydrated throughout the day.
Avoid known food allergens.

💼 Impact on Daily Work & Life

This medicine may cause mild drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue normal daily activities, but caution is advised.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as mood changes, severe allergic reactions, or liver problems, seek immediate medical advice. Your doctor will determine if and when to stop the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well-tolerated. However, Montelukast has been associated with rare neuropsychiatric events. Regular monitoring of mood and behavior is advised. Liver function should be monitored if symptoms occur. Do not stop asthma controller therapy without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Allergen avoidance

Reducing exposure to allergens can help control symptoms.

Evidence: Well-established
Immunotherapy

Allergy shots or sublingual tablets can provide long-term relief.

Evidence: Well-established
Nasal saline irrigation

Helps clear nasal passages and reduce allergy symptoms.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. Continue routine vaccinations as recommended by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, continue taking once daily at your usual time. Check customs regulations for carrying prescription medicines. Keep enough supply for your entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with seasonal allergic rhinitis and mild asthma
She was prescribed this medicine once daily. After two weeks, her sneezing and runny nose improved significantly, and she had fewer asthma symptoms. She reported mild drowsiness initially, which resolved after a few days.
💡 Lesson: Consistent daily use improves both allergy and asthma control. Mild side effects often subside with continued use.
👤 A 45-year-old man with chronic urticaria and allergic rhinitis
He started this medicine and noticed reduced itching and hives within a week. He was advised to avoid alcohol and to report any mood changes. He experienced no serious side effects.
💡 Lesson: This medicine can effectively manage multiple allergic conditions simultaneously. Regular follow-up is important to monitor for rare side effects.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Desloratadine starts relieving allergy symptoms within 1 hour. Montelukast may take several days to reach full effect for asthma control.

Q: Can I take this medicine with food?

A: Yes, this medicine can be taken with or without food. Taking it with food may reduce stomach upset.

Q: Is it safe to take this medicine during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy. The safety profile is not fully established.

Q: Can I stop taking this medicine suddenly?

A: Do not stop this medicine suddenly without consulting your doctor, especially if you have asthma.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my liver function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allerde m tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used to treat acute asthma attacks.
    Fact: This medicine is not a rescue inhaler and should not be used for immediate relief of an acute asthma attack.
  • Myth: This medicine is safe for children under 15 years.
    Fact: This medicine is not recommended for children under 15 years unless prescribed by a pediatrician.
  • Myth: It is safe to drink alcohol while taking this medicine.
    Fact: Alcohol may increase drowsiness and dizziness; it is best to avoid alcohol.

🔄 Alternative Options

Generic Alternatives

  • Desloratadine + Montelukast combination tablets from other manufacturers

Brand Alternatives

  • Alorti-M Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Desloratadine + Montelukast","composition":"Desloratadine 5 mg + Montelukast 10 mg","onset":"1 hour for antihistamine; days for Montelukast","duration":"24 hours","notes":"Combined antihistamine and leukotriene blocker."},{"medicine":"Levocetirizine + Montelukast","composition":"Levocetirizine 5 mg + Montelukast 10 mg","onset":"1 hour for antihistamine; days for Montelukast","duration":"24 hours","notes":"Levocetirizine may cause more drowsiness."}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory