Digitran 0.25mg Tablet (Digoxin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- A pulse that is very slow, very fast, or irregular
- Fainting or near-fainting
- Severe nausea, vomiting, or loss of appetite
- Blurred vision or seeing yellow-green halos around objects
- Confusion, unusual drowsiness, or hallucinations
- Chest pain or worsening breathlessness
- Swelling of the face, lips, or throat, or difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is sangoxin 0.25mg tablet used for?
This medicine contains Digoxin 0.25 mg and is used to treat heart failure and to control certain fast or irregular heart rhythms such as atrial fibrillation. It strengthens the heartbeat and slows conduction through the heart, but it has a narrow safety range, so regular blood tests and heart monitoring are essential.
- Generic Name: Digoxin (0.25mg)
- Manufacturer: Sanofi India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sangoxin 0.25mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डिगॉक्सिन 0.25 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग मुख्य रूप से हृदय विफलता (हार्ट फेल्योर) और अनियमित तथा तेज़ धड़कन जैसे एट्रियल फाइब्रिलेशन के इलाज में किया जाता है। यह हृदय की धड़कन को मज़बूत बनाती है और हृदय की ऊपरी कोठरियों से होकर जाने वाले विद्युत संकेतों को धीमा करती है, जिससे दिल की कार्यक्षमता बेहतर होती है और सांस फूलना, थकान तथा पैरों में सूजन जैसे लक्षण कम होते हैं। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए और इसकी खुराक बहुत सावधानी से तय की जाती है, क्योंकि इसका सुरक्षित स्तर बहुत संकीर्ण होता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, भूख न लगना, दस्त, चक्कर आना, सिरदर्द और थकान शामिल हैं। कुछ लोगों में स्तनों में कोमलता या बढ़ोतरी भी देखी जा सकती है। गंभीर दुष्प्रभावों में दिल की धड़कन में खतरनाक अनियमितता, धड़कन का बहुत धीमा हो जाना, भ्रम, धुंधली दृष्टि या पीले-हरे रंग के घेरे दिखना शामिल हैं। अगर धड़कन बहुत तेज़ या बहुत धीमी लगे, बेहोशी आए या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर द्वारा बताई गई खुराक और समय पर ही लें, और अपनी मर्जी से खुराक न बदलें। नियमित रूप से खून की जांच, ईसीजी और डॉक्टर के पास जांच कराते रहें, क्योंकि इस दवा का स्तर शरीर में बढ़ने पर नुकसानदायक हो सकता है। किसी भी नई दवा को शुरू करने से पहले अपने डॉक्टर को बताएं कि आप यह दवा ले रहे हैं। जी मिचलाना, उल्टी, दृष्टि में बदलाव, भ्रम या धड़कन का बहुत धीमा होना जैसे लक्षण दिखें तो तुरंत चिकित्सा सहायता लें। पोटैशियम की मात्रा इस दवा को प्रभावित करती है, इसलिए बिना डॉक्टर की सलाह के पोटैशियम सप्लीमेंट या नमक के विकल्प न लें।
💊 sangoxin 0.25mg tablet Uses & Benefits
[{"condition":"Heart failure with reduced ejection fraction","description":"This medicine is used to improve symptoms and reduce hospitalisations in selected patients with heart failure, usually in addition to other standard heart failure medicines.","evidence":"Well-established"},{"condition":"Atrial fibrillation with rapid ventricular response","description":"This medicine helps slow the heart rate in patients with atrial fibrillation, especially when other rate-control medicines are not fully effective or not tolerated.","evidence":"Well-established"},{"condition":"Atrial flutter with rapid ventricular response","description":"This medicine may be used to control the ventricular rate in atrial flutter when clinically appropriate.","evidence":"Established"},{"condition":"Supraventricular tachycardia","description":"This medicine can be used in selected cases to slow conduction and help control certain supraventricular tachycardias.","evidence":"Established"}]
Off-label uses: [{"condition":"Fetal supraventricular tachycardia","description":"In specialised fetal medicine settings, Digoxin may be used to treat certain fetal arrhythmias under expert supervision.","evidence":"Limited"},{"condition":"Rapid ventricular rate in critically ill patients with atrial fibrillation","description":"In some intensive care situations, Digoxin may be considered when other rate-control options are unsuitable.","evidence":"Limited"}]
Primary treatment for: Heart failure and atrial fibrillation
Also treats: Atrial flutter, Supraventricular tachycardia, Heart failure with reduced ejection fraction
📋 Drug Information
| Generic Name(s) | Digoxin (0.25mg) |
| Brand Name | sangoxin 0.25mg tablet |
| Manufacturer | Sanofi India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Cardiac glycosides |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15 and 30 degrees Celsius in a dry place, away from direct sunlight and moisture. Keep the tablets in their original container and out of reach of children. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture, depending on the manufacturer. Always check the expiry date printed on the pack before use. |
| WHO Guideline | Not established from the available information for this specific product. Digoxin remains an option in selected patients with heart failure and in rate control for atrial fibrillation according to major cardiology guidelines, but the exact recommendations should be checked in the latest official guideline documents. |
| ICMR Guideline | Not established from the available information for this specific product. Clinicians in India generally follow standard cardiology practice and national heart failure guidance when prescribing Digoxin. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Digoxin inhibits the sodium-potassium adenosine triphosphatase pump in cardiac cell membranes. This inhibition raises intracellular sodium, which reduces calcium extrusion through the sodium-calcium exchanger and increases intracellular calcium available to the contractile proteins. The result is a stronger force of cardiac contraction, known as a positive inotropic effect. Digoxin also increases vagal tone and slows conduction through the atrioventricular node, which helps control fast atrial rhythms such as atrial fibrillation.
Mechanism Steps
💡 How to Take sangoxin 0.25mg tablet
Strength: Immediate-release tablet containing Digoxin 0.25 mg
Dosage Information
| Adult Dosage | The usual adult maintenance dose of this medicine is individualised and commonly ranges from 0.125 mg to 0.25 mg once daily, but the exact dose depends on the indication, age, kidney function, other medicines, and Digoxin blood levels. Some patients, especially older adults or those with reduced kidney function, need lower doses such as 0.125 mg daily or every other day. A loading dose may sometimes be used in hospital under close supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and regular monitoring. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific product. Digoxin is used in children only under specialist supervision with carefully calculated weight-based doses. Consult a pediatrician or pediatric cardiologist. |
| Elderly Dosage | Older adults are more sensitive to Digoxin and are at higher risk of toxicity. Lower maintenance doses, such as 0.125 mg daily or less, are often used, and kidney function and Digoxin levels should be checked regularly. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Digoxin is eliminated mainly by the kidneys, so patients with reduced kidney function need lower doses and careful monitoring. The dose should be adjusted according to kidney function and Digoxin blood levels, and must be individualized by a qualified clinician. |
| Hepatic Impairment | Liver function has only a minor role in Digoxin elimination, so significant dose adjustment for liver disease alone is usually not required. However, any dose change should be made by a qualified clinician who considers the whole clinical picture. |
| Maximum Daily Dose | The maximum daily dose is individualised and must not exceed the dose determined by a qualified clinician based on the patient's condition, kidney function, and Digoxin blood levels. In most adults, maintenance doses above 0.25 mg daily are rarely used outside specialist supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sangoxin 0.25mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Verapamil | Major | |
| Quinidine | Major | |
| Potassium-losing diuretics | Major | |
| Diltiazem | Major | |
| Antacids | Moderate | |
| Macrolide antibiotics | Moderate | |
| Corticosteroids | Moderate | |
| Beta-blockers | Moderate | |
| High-fibre supplements | Minor |
🚨 Major Interactions
- Amiodarone
- Verapamil
- Quinidine
- Diuretics that cause potassium loss
- Calcium channel blockers such as diltiazem
⚡ Moderate Interactions
- Antacids
- Some antibiotics such as macrolides
- Corticosteroids
- Beta-blockers
🍷 Alcohol Interaction
Alcohol can worsen heart failure and may affect blood pressure and heart rhythm. It is best to avoid alcohol or limit it strictly while taking this medicine, and to discuss any alcohol use with your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to Digoxin or any component of the tablet","Ventricular fibrillation","Second or third degree heart block without a functioning pacemaker","Certain other severe bradyarrhythmias","Wolff-Parkinson-White syndrome with atrial fibrillation, unless managed by a specialist"]
⚠️ Warnings & Precautions
["Use with caution in older adults, who are more prone to Digoxin toxicity.","Dose adjustment is needed in patients with reduced kidney function.","Monitor potassium and magnesium levels closely, as abnormalities increase the risk of toxicity.","Use with caution in patients with thyroid disease, as both underactive and overactive thyroid can change Digoxin effects.","Avoid abrupt discontinuation without medical advice, because heart failure or rhythm problems may worsen.","Tell your doctor about all other medicines, including over-the-counter products and herbal supplements."]
🤱 Lactation Safety
Digoxin passes into breast milk in small amounts. It is generally considered compatible with breastfeeding, but the baby should be monitored and the decision should be made with a doctor.
💊 Overdose Management
Overdose of this medicine is a medical emergency and can cause severe heart rhythm disturbances, nausea, vomiting, confusion, and visual changes. If an overdose is suspected, contact emergency services immediately and go to the nearest hospital. Treatment is supportive and may include monitoring in a coronary care unit, correction of electrolyte abnormalities, and in severe cases the use of specific antidotes such as Digoxin immune Fab under specialist care. Do not try to treat an overdose at home.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if less than half the usual dosing interval has passed. If more than half the interval has passed, skip the missed dose and continue with your regular schedule. Never take two doses at the same time to make up for a missed dose, because this can cause dangerous Digoxin levels.
Additional Safety Advice
Take this medicine exactly at the dose and time advised by your doctor, and never change the dose on your own. Keep all appointments for blood tests, electrocardiograms, and clinical review, because the balance between benefit and harm can change quickly. Tell every doctor, dentist, or pharmacist who treats you that you are taking this medicine, especially before any new medicine is started. Learn the warning signs of too much Digoxin, such as nausea, vomiting, visual changes, confusion, or an unusually slow or irregular pulse, and seek medical help if they occur. Do not use salt substitutes or potassium supplements unless your doctor specifically prescribes them, because potassium levels strongly affect how this medicine works. Store the tablets safely away from children and check the expiry date before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are at higher risk of Digoxin toxicity because of reduced kidney function and other medicines. Lower doses are often needed, and regular checks of Digoxin levels, potassium, kidney function, and heart rate are especially important. Watch for confusion, falls, and loss of appetite, which may be signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, speak to your doctor before making any changes to this medicine. Digoxin may be used in pregnancy when needed, but the dose may need adjustment and close monitoring is required. Do not stop or start this medicine without medical advice.
🏥 Post-Surgery Considerations
After surgery, your doctor will decide when and how to continue this medicine. Inform the surgical and anaesthesia team that you take Digoxin, because it can affect heart rate and rhythm during and after surgery. Blood levels and heart monitoring may be needed in the postoperative period.
🦷 Dental Procedures
Tell your dentist that you take this medicine before any dental procedure. Some dental medicines and local anaesthetics can interact with heart medicines, and your dentist may need to consult your doctor. Keep taking your regular dose unless your doctor advises otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular physical activity is good for heart health, but you should follow the exercise plan advised by your doctor. Avoid strenuous or competitive exercise if you have heart failure or heart rhythm problems, and stop immediately if you feel chest pain, severe breathlessness, dizziness, or palpitations. Warm up and cool down gradually, and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness, tiredness, or visual changes in some people, which may affect driving or operating machinery. Avoid driving or hazardous tasks until you know how the medicine affects you. Most people can continue their usual work and daily activities once the dose is stable, but you should discuss any job that involves heavy physical exertion or safety-sensitive tasks with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Stopping suddenly can worsen heart failure or heart rhythm problems. Your doctor may reduce or stop the medicine if your condition changes, if side effects occur, or if blood levels become unsafe. Always discuss any decision to stop with your prescriber.
📅 Long-Term Use Effects
Long-term use of this medicine can be safe and effective when the dose is carefully adjusted and monitored. Regular blood tests for Digoxin levels, potassium, and kidney function are needed because the safe range is narrow. Over time, the dose may need to be changed if kidney function declines or if other medicines are added. Long-term use should be reviewed periodically by your doctor to confirm that the benefits still outweigh the risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines such as metoprolol or carvedilol are often used for heart failure and rate control and may be used instead of or with Digoxin.
Evidence: Well-establishedCertain calcium channel blockers can help control heart rate in atrial fibrillation when appropriate.
Evidence: Well-establishedA procedure that can control certain heart rhythm problems and reduce the need for long-term rate-control medicines in selected patients.
Evidence: EstablishedSalt restriction, daily weight monitoring, and supervised exercise support heart failure management alongside medicines.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no specific vaccine interaction with this medicine. However, people with heart failure should discuss influenza and pneumococcal vaccination with their doctor, as infections can worsen heart failure. Follow your doctor's advice on routine vaccinations.
📦 Storage Guide
✅ DO
Store at room temperature between 15 and 30 degrees Celsius
❌ DON'T
Do not store in the refrigerator unless the label says so
✅ DO
Keep the tablets in their original container
❌ DON'T
Do not transfer them to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original labelled packaging with a copy of your prescription, especially for air travel or international trips. Keep enough supply for the entire journey plus extra in case of delays. Store the tablets at room temperature and away from direct sunlight and moisture. If you cross time zones, keep your dosing schedule as close to every 24 hours as possible and ask your doctor in advance about any adjustments. Declare the medicine at customs if required and carry a doctor's letter listing your condition and medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some effects can be noticed within hours, but the full benefit for heart failure or heart rate control may take several days to a few weeks, depending on your condition and other treatments.
A: Nausea, vomiting, loss of appetite, blurred vision or yellow-green halos, confusion, and a very slow or irregular pulse can be signs of too much Digoxin. Seek medical help promptly if these occur.
A: No. This medicine is often needed long term, and stopping it suddenly can worsen heart failure or heart rhythm problems. Always speak to your doctor before making any change.
A: Yes. It can interact with several medicines, including amiodarone, verapamil, quinidine, some diuretics, and certain antibiotics. Always tell your doctor about all medicines you take.
A: Older adults are more sensitive to Digoxin and need lower doses with closer monitoring. Your doctor will adjust the dose based on your kidney function and blood levels.
🤔 Common Patient Concerns
🔄 Substitutes for sangoxin 0.25mg tablet
View AllAlternative brands with exact same active ingredient:
-
digitran 0.25mg tabletMacleods Pharmaceuticals Pvt Ltd ₹5.52 38.2% CHEAPER
-
cardioxin 0.25mg tabletNovartis India Ltd ₹7.10 20.5% CHEAPER
-
digoxin 0.25mg tabletGlaxo SmithKline Pharmaceuticals Ltd ₹7.25 18.8% CHEAPER
-
celoxin 0.25mg tabletCelon Laboratories Ltd ₹8.91 0.2% CHEAPER
-
geoxin 0.25mg tabletGeo Pharma Pvt Ltd ₹9.38 5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once you feel better.
Fact: This medicine is often needed long term, and stopping it suddenly can worsen heart failure or heart rhythm problems. Always speak to your doctor before stopping. - Myth: More of this medicine will make the heart stronger faster.
Fact: Taking more than the prescribed dose can cause serious heart rhythm problems and other toxic effects. The dose must be carefully individualised. - Myth: Blood tests are not needed if you feel fine.
Fact: Regular blood tests are essential because Digoxin levels can become unsafe even when you feel well. - Myth: This medicine is a general tonic for the heart.
Fact: This medicine is a specific cardiac glycoside used for particular heart conditions, not a general heart tonic.
🔄 Alternative Options
Generic Alternatives
- Digoxin 0.25 mg tablet
Brand Alternatives
- Digitran 0.25 mg tablet