Aldome Capsule (Domperidone 20mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Palpitations, irregular heartbeat, or fainting
- Unusual muscle stiffness, spasms, or restlessness
- Severe abdominal pain or blood in vomit or stool
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes
- Severe dizziness or confusion
- Chest pain or difficulty breathing
If experiencing severe symptoms, call emergency services immediately.
What is casdom 20mg tablet used for?
This medicine contains Domperidone 20mg, which is used to treat nausea, vomiting, and symptoms of delayed stomach emptying such as bloating and fullness. It works by blocking dopamine receptors in the brain and gut. It is usually taken before meals for short periods. It should be avoided in people with certain heart conditions or liver disease.
- Generic Name: Domperidone
- Manufacturer: Casca Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 casdom 20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन 20 मिलीग्राम कैप्सूल के रूप में उपलब्ध है और मुख्य रूप से उल्टी, जी मिचलाना, पेट भारी लगना और पेट की गैस जैसी समस्याओं के इलाज के लिए इस्तेमाल की जाती है। यह दवा पेट और आंतों की गति को बढ़ाकर भोजन को जल्दी पचाने में मदद करती है और उल्टी की भावना को कम करती है। यह दवा आमतौर पर खाने से पहले ली जाती है और इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए। यह दवा उन लोगों के लिए नहीं है जिन्हें दिल की धड़कन से जुड़ी समस्या है, लीवर की गंभीर बीमारी है, या जिन्हें पेट में रक्तस्राव या रुकावट है। इस दवा को लंबे समय तक बिना डॉक्टर की सलाह के नहीं लेना चाहिए क्योंकि इससे दिल की धड़कन में गड़बड़ी हो सकती है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मुँह सूखना, सिरदर्द, पेट में हल्की ऐंठन, दस्त और नींद आना शामिल हैं। कुछ लोगों में स्तनों में दर्द, सूजन या दूध का स्राव हो सकता है, और महिलाओं में मासिक धर्म अनियमित हो सकता है। ये प्रभाव आमतौर पर दवा बंद करने पर ठीक हो जाते हैं। बहुत कम मामलों में यह दवा दिल की धड़कन में गंभीर गड़बड़ी, बेचैनी, मांसपेशियों में अकड़न या असामान्य हरकतें पैदा कर सकती है। अगर आपको धड़कन तेज होना, बेहोशी, चक्कर आना या मांसपेशियों में असामान्य हरकत महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर खाने से पहले। अपनी मर्जी से दवा की मात्रा न बढ़ाएँ और न ही लंबे समय तक लें। इस दवा के साथ शराब न पिएँ क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। अगर आपको दिल, लीवर या किडनी की बीमारी है, तो डॉक्टर को पहले बताएँ। गर्भवती या स्तनपान कराने वाली महिलाएँ बिना डॉक्टर की सलाह के यह दवा न लें। इस दवा को बच्चों की पहुँच से दूर रखें। अगर आपको धड़कन तेज होना, बेहोशी, मांसपेशियों में अकड़न या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से मिलें।
💊 casdom 20mg tablet Uses & Benefits
[{"condition":"Nausea and vomiting","description":"This medicine is used for the short-term relief of nausea and vomiting of various causes, including that associated with gastritis, migraine, or certain medicines.","evidence":"Well-established"},{"condition":"Delayed gastric emptying (gastroparesis) symptoms","description":"It helps to reduce symptoms such as bloating, early fullness, and upper abdominal discomfort by improving the coordination of stomach contractions.","evidence":"Moderate"},{"condition":"Functional dyspepsia","description":"Sometimes prescribed to relieve postprandial fullness and epigastric discomfort in people with functional dyspepsia.","evidence":"Limited"},{"condition":"Gastro-oesophageal reflux disease (GERD) adjunct","description":"May be used as an add-on to other treatments to reduce nausea and improve gastric emptying in some patients with GERD.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Occasionally used off-label to improve gastric emptying in diabetic patients with gastroparesis, but evidence is limited and other treatments are preferred.","evidence":"Limited"},{"condition":"Nausea in Parkinson's disease","description":"Sometimes used off-label for nausea in Parkinson's disease, but it must be used with caution because it can worsen parkinsonian symptoms.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting
Also treats: Gastroparesis, Functional dyspepsia, Gastro-oesophageal reflux disease
📋 Drug Information
| Generic Name(s) | Domperidone |
| Brand Name | Actidom 5mg Oral Suspension |
| Manufacturer | Casca Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Dopamine (D2) receptor antagonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture, or as stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Domperidone is a peripherally acting dopamine D2 receptor antagonist. It blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) located outside the blood-brain barrier, which reduces the nausea and vomiting signals. It also acts on D2 receptors in the stomach and duodenum to enhance gastric peristalsis and accelerate gastric emptying, while relaxing the pyloric sphincter. Because it does not readily cross the blood-brain barrier, it causes fewer central nervous system side effects than some other dopamine antagonists, although extrapyramidal effects can still occur, especially in children. Domperidone also increases prolactin release from the pituitary gland by blocking dopamine inhibition.
Mechanism Steps
💡 How to Take casdom 20mg tablet
Strength: Domperidone 20 mg immediate-release capsule
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mg to 20 mg taken up to three times a day before meals, depending on the indication and severity of symptoms. For nausea and vomiting, the usual dose is 10 mg to 20 mg every 4 to 6 hours as needed, but the maximum daily dose should not exceed 80 mg. For gastroparesis, the dose is typically 10 mg to 20 mg three to four times a day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration of treatment. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Domperidone is generally not recommended for children due to increased risk of extrapyramidal side effects. |
| Elderly Dosage | Elderly patients may be more sensitive to the cardiac and extrapyramidal effects of domperidone. Use with caution and consider starting at a lower dose. Dose must be individualized by a qualified clinician based on renal and hepatic function and concomitant medications. |
| Renal Impairment | In patients with severe renal impairment, the elimination half-life of domperidone may be prolonged. Dose reduction may be necessary. Consult your doctor for dose adjustment. |
| Hepatic Impairment | Domperidone is contraindicated in patients with moderate to severe hepatic impairment. In mild hepatic impairment, use with caution and consider dose reduction. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 80 mg per day for adults, but the lowest effective dose should be used for the shortest duration. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of casdom 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Amiodarone | Major | |
| Haloperidol | Major | |
| Ritonavir | Major | |
| Diltiazem | Moderate | |
| Fluoxetine | Moderate | |
| Rifampicin | Moderate | |
| Atropine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, fluconazole, voriconazole (azole antifungals)
- Clarithromycin, erythromycin, telithromycin (macrolide antibiotics)
- Amiodarone, sotalol, quinidine, disopyramide, dofetilide (antiarrhythmics)
- Haloperidol, chlorpromazine, thioridazine (antipsychotics)
- Ritonavir, saquinavir, indinavir (protease inhibitors)
⚡ Moderate Interactions
- Diltiazem, verapamil (calcium channel blockers)
- Fluoxetine, paroxetine (SSRIs)
- Rifampicin
- Anticholinergic medicines (e.g., atropine, hyoscine)
🍷 Alcohol Interaction
Alcohol may increase the sedative effects of domperidone and can worsen dizziness or drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone or any component of the capsule","Prolactin-releasing pituitary tumour (prolactinoma)","Gastrointestinal bleeding, mechanical obstruction, or perforation","Moderate to severe hepatic impairment","Known existing QT interval prolongation or congenital long QT syndrome","Concomitant use with potent CYP3A4 inhibitors that prolong QT interval (e.g., ketoconazole, clarithromycin)","Concomitant use with QT-prolonging drugs (e.g., amiodarone, sotalol)"]
⚠️ Warnings & Precautions
["Use the lowest effective dose for the shortest possible duration, as high doses and long-term use increase the risk of serious cardiac arrhythmias.","Avoid in patients with severe heart failure, electrolyte abnormalities, or bradycardia unless clearly necessary and under close monitoring.","Use with caution in elderly patients, who are more susceptible to cardiac and extrapyramidal side effects.","Domperidone may cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use in children without specialist advice due to increased risk of extrapyramidal reactions.","Inform your doctor if you have kidney or liver disease, as dose adjustment may be needed.","Avoid alcohol while taking this medicine as it may increase drowsiness.","Do not take this medicine for longer than 7 days without consulting your doctor."]
🤱 Lactation Safety
Domperidone is excreted in breast milk in small amounts. It is sometimes used off-label to increase milk supply, but this is not recommended due to potential cardiac risks to the mother. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of domperidone may cause drowsiness, disorientation, extrapyramidal reactions, and QT prolongation with risk of ventricular arrhythmias. There is no specific antidote. Treatment is supportive and symptomatic. Activated charcoal may be given if the overdose is recent. ECG monitoring is recommended. Contact a poison control centre or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually before meals, because food can slightly delay its absorption but improves its effect on stomach emptying. Do not take more than the recommended dose, and do not use it for longer than your doctor advises, as long-term high-dose use increases the risk of heart rhythm problems. Avoid drinking alcohol while taking this medicine because it can worsen drowsiness and dizziness. If you have heart disease, liver disease, kidney disease, or an electrolyte imbalance, tell your doctor before starting this medicine. Do not take this medicine if you are allergic to domperidone or any of the capsule ingredients. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of the reach of children. Do not share this medicine with others, even if they have similar symptoms. If you experience palpitations, fainting, unusual muscle movements, or severe abdominal pain, stop the medicine and contact your doctor immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the cardiac and extrapyramidal side effects of this medicine. Use with caution, start at a lower dose, and monitor for palpitations, dizziness, and muscle stiffness. Avoid concomitant use with other QT-prolonging drugs.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not fully established. It should only be used if clearly needed and prescribed by a doctor.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to treat nausea and vomiting, but it should be used with caution in patients with underlying heart disease or electrolyte imbalances. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain medicines used during dental procedures, and it can cause dry mouth, which may affect dental health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild to moderate exercise is generally safe while taking this medicine. However, if you experience dizziness, drowsiness, or palpitations, avoid strenuous exercise and consult your doctor. Do not start any new exercise regimen without medical advice if you have heart disease.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually taken before meals, so it may need to be scheduled around your work breaks. Inform your employer if your job involves operating machinery or driving.
🛑 When to Stop This Medicine
Stop taking this medicine if your doctor advises you to, or if you experience serious side effects such as palpitations, fainting, unusual muscle movements, or severe allergic reactions. Do not stop suddenly without consulting your doctor if you have been on long-term therapy. Always consult your doctor before stopping this medicine.
📅 Long-Term Use Effects
Long-term use of this medicine, especially at high doses, is associated with an increased risk of serious heart rhythm problems such as QT prolongation and ventricular arrhythmias. It may also cause persistent hyperprolactinaemia leading to breast tenderness, galactorrhoea, and menstrual irregularities. Regular monitoring of heart rhythm and prolactin levels may be required if long-term use is unavoidable. It is generally recommended to use this medicine for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, low-fat meals can help reduce nausea and bloating.
Evidence: Well-establishedGinger has antiemetic properties and may help reduce mild nausea.
Evidence: ModerateAcupuncture at the P6 point may help reduce nausea and vomiting.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually to match your new meal times, but do not take extra doses. Check the customs regulations of your destination country regarding prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: It is best taken 15 to 30 minutes before meals. Taking it after food may delay its effect.
A: It should only be taken for the duration prescribed by your doctor, usually short-term. Long-term use increases the risk of heart rhythm problems.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is advisable to avoid alcohol while taking this medicine as it can increase drowsiness and dizziness.
🤔 Common Patient Concerns
🔄 Substitutes for casdom 20mg tablet
View AllAlternative brands with exact same active ingredient:
-
dompil 20mg tabletPsychotropics India Ltd ₹3.12 91.8% CHEAPER
-
domperon 20mg tabletCadila Pharmaceuticals Ltd ₹17.77 53.2% CHEAPER
-
novadom 20mg tablet mdPacific Drugs & Chemicals ₹27.66 27.2% CHEAPER
-
vom 20mg tabletVintech Formulations ₹33.98 10.6% CHEAPER
-
makdom 20mg tabletTrimak Lifesciences ₹35.63 6.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Domperidone is a harmless medicine that can be taken for any stomach problem.
Fact: Domperidone can cause serious heart rhythm problems, especially at high doses or with certain other medicines. It should only be used when prescribed and for the recommended duration. - Myth: Domperidone is safe to take during pregnancy without any risk.
Fact: The safety of domperidone during pregnancy is not fully established. It should only be used if clearly needed and prescribed by a doctor. - Myth: Domperidone can be taken indefinitely for chronic stomach issues.
Fact: Long-term use of domperidone is not recommended due to the risk of cardiac side effects. It should be used for the shortest duration possible.
🔄 Alternative Options
Generic Alternatives
- Domperidone 20 mg capsule
- Domperidone 10 mg tablet
Brand Alternatives
- Domstal 20 mg capsule
- Vomikind 20 mg capsule
- Domperidone 20 mg capsule (various manufacturers)