carion-e soft gelatin capsule - Uses, Price, Side Effects & Substitutes
What is carion-e soft gelatin capsule used for?
Carvi 500mg/50mg Tablet (Levocarnitine + Vitamin E) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Levo-carnitine (200mg) + Vitamin E (400IU), which Levocarnitine facilitates transport of long-chain fatty acids into mitochondria . Always consult your doctor before use. Take as prescribed.
- Generic Name: Levocarnitine + Vitamin E
- Manufacturer: Shinto Organics (P) Limited
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ carion-e soft gelatin capsule Uses & Benefits
Carnitine deficiency, primary and secondary; antioxidant therapy; adjunct in cardiovascular diseases; chronic fatigue syndrome.
Off-label uses: Male infertility, diabetic neuropathy, Alzheimer's disease (limited evidence).
๐ Drug Information
| Generic Name(s) | Levocarnitine + Vitamin E |
| Brand Name | Carvi 500mg/50mg Tablet |
| Manufacturer | Shinto Organics (P) Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Carnitine supplement; Antioxidant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Levocarnitine facilitates transport of long-chain fatty acids into mitochondria for beta-oxidation; Vitamin E acts as a lipid-soluble antioxidant, protecting cell membranes from oxidative damage.
Mechanism Steps
๐ก How to Take carion-e soft gelatin capsule
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of carion-e soft gelatin capsule
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Fishy body odor (levocarnitine)
- Abdominal cramps
๐จ Serious Side Effects
- Seizures (rare)
- Thrombocytopenia (Vitamin E high doses)
- Bleeding (with anticoagulants)
โ ๏ธ Rare Side Effects
- Allergic reactions
- Rash
- Hyperphosphatemia (in renal patients)
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk due to Vitamin E antagonism of Vitamin K |
| Orlistat | Moderate | Reduced absorption of Vitamin E |
| Cholestyramine | Moderate | Reduced absorption of Vitamin E |
| Thyroid hormones | Major | Levocarnitine may inhibit thyroid hormone action |
๐จ Major Interactions
- Warfarin
- Anticoagulants
- Thyroid hormones
โก Moderate Interactions
- Orlistat
- Cholestyramine
- Colestipol
โน๏ธ Minor Interactions
- Iron supplements
- Zinc supplements
๐ฝ๏ธ Food Interactions
High-fat meals increase Vitamin E absorption, Dairy products may reduce levocarnitine absorption
๐ท Alcohol Interaction
Alcohol may reduce levocarnitine levels and increase oxidative stress.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component; severe renal impairment (levocarnitine accumulation).
๐ Monitoring Parameters
Carnitine levels (plasma), liver function, renal function, coagulation profile (if on warfarin).
๐คฑ Lactation Safety
Levocarnitine is excreted in breast milk; Vitamin E is present in breast milk. Use with caution.
๐ Overdose Management
Gastric lavage if recent; symptomatic and supportive care; levocarnitine is dialyzable.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip missed dose if close to next dose.