capofin 70mg injection - Uses, Price, Side Effects & Substitutes
What is capofin 70mg injection used for?
Asponet 50 Injection (Caspofungin) is used to treat OTHERS. It contains Caspofungin (70mg), which Inhibits synthesis of beta-(1,3)-D-glucan, an essential component of fungal cell. Always consult your doctor before use. Take as prescribed.
- Generic Name: Caspofungin
- Manufacturer: Intas Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ capofin 70mg injection Uses & Benefits
Invasive candidiasis, esophageal candidiasis, invasive aspergillosis (refractory or intolerant to other therapies), empirical therapy for febrile neutropenia.
Off-label uses: Candidemia in neonates, Endocarditis due to Candida, Osteomyelitis due to Candida
๐ Drug Information
| Generic Name(s) | Caspofungin |
| Brand Name | Asponet 50 Injection |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OTHERS |
| Action Class | Fungal cell wall synthesis inhibitor (Echiocandins) |
| Route of Administration | Intravenous infusion. |
| Storage | Store at 2-8ยฐC. Do not freeze. Protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits synthesis of beta-(1,3)-D-glucan, an essential component of fungal cell walls.
Mechanism Steps
๐ก How to Take capofin 70mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of capofin 70mg injection
โ Common Side Effects
- Fever
- Nausea
- Vomiting
- Diarrhea
- Headache
- Phlebitis
- Elevated liver enzymes
๐จ Serious Side Effects
- Anaphylaxis
- Hepatotoxicity
- Renal impairment
- Hemolytic anemia
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Pancreatitis
- Seizures
- Pulmonary edema
- Thrombotic thrombocytopenic purpura
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cyclosporine | Major | Increased risk of hepatotoxicity |
| Tacrolimus | Major | Reduced tacrolimus levels |
| Rifampin | Major | Reduced caspofungin efficacy |
| Efavirenz | Major | Reduced caspofungin levels |
| Nevirapine | Major | Reduced caspofungin levels |
| Phenytoin | Major | Reduced caspofungin levels |
| Dexamethasone | Major | Reduced caspofungin levels |
| Carbamazepine | Major | Reduced caspofungin levels |
| Sirolimus | Moderate | Possible increased sirolimus levels |
| Nifedipine | Moderate | Possible increased nifedipine levels |
| Midazolam | Moderate | Possible increased midazolam levels |
๐จ Major Interactions
- Cyclosporine
- Tacrolimus
- Rifampin
- Efavirenz
- Nevirapine
- Phenytoin
- Dexamethasone
- Carbamazepine
โก Moderate Interactions
- Sirolimus
- Nifedipine
- Midazolam
โน๏ธ Minor Interactions
- Itraconazole
- Posaconazole
- Voriconazole
๐ฝ๏ธ Food Interactions
None (IV administration).
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to caspofungin or any component.
๐ Monitoring Parameters
Liver function tests, renal function, complete blood count, signs of infusion reactions.
๐คฑ Lactation Safety
Unknown; caution advised.
๐ Overdose Management
Supportive care; no specific antidote. Hemodialysis not effective.
โฐ Missed Dose
Administer as soon as remembered; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for capofin 70mg injection
View AllAlternative brands with exact same active ingredient (Caspofungin (70mg)):
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Medical Note: Always consult your doctor before switching medications.