Levosulpiride 25mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Palpitations, fainting, or chest discomfort
- High fever with severe muscle stiffness or confusion
- Uncontrolled movements of the face, tongue, or limbs
- Yellowing of the eyes or skin, or dark urine
- Severe abdominal pain or persistent vomiting
- Swelling of the face, lips, or throat, or difficulty breathing
- Unusual bruising or bleeding
- Decreased urine output or swelling in the legs
If experiencing severe symptoms, call emergency services immediately.
What is c-pride 25mg tablet used for?
This medicine contains Levosulpiride 25mg, a dopamine D2 receptor antagonist with prokinetic action. It is used to treat nausea, vomiting, functional dyspepsia, and diabetic gastroparesis. It works by blocking dopamine receptors in the brain and gut, which reduces nausea and helps the stomach empty faster. It is usually taken before meals, and the dose must be individualized by a doctor.
- Generic Name: Levosulpiride
- Manufacturer: Cause & Cure Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 c-pride 25mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसल्पिराइड 25mg से बनी है और मुख्य रूप से उल्टी, जी मिचलाना, पेट भरा-भरा लगना, अपच और डायबिटीज से जुड़ी पेट की धीमी खाली होने की समस्या में दी जाती है। यह दवा पेट और दिमाग में डोपामिन नाम के रसायन को रोककर काम करती है, जिससे उल्टी कम होती है और पेट जल्दी खाली होता है। इसे डॉक्टर की सलाह पर ही लेना चाहिए और खाने से पहले लेना बेहतर होता है।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, सिरदर्द, मुँह सूखना और कब्ज शामिल हैं। कुछ लोगों को थकान या पेट में हल्की गड़बड़ी भी हो सकती है। कभी-कभी स्तनों में दर्द या दूध जैसा स्राव, माहवारी में बदलाव, या मांसपेशियों में अकड़न जैसी समस्या हो सकती है। अगर दिल की धड़कन तेज या अनियमित लगे, बुखार के साथ मांसपेशियों में अकड़न हो, या बेकाबू हरकतें हों, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, अपने मन से मात्रा न बढ़ाएँ और न घटाएँ। इसे पानी के साथ निगलें, आमतौर पर खाने से पहले लेना बेहतर होता है। जब तक पता न चले कि इस दवा से आपको कैसा लगता है, गाड़ी चलाने या मशीन चलाने से बचें, क्योंकि इससे नींद और चक्कर आ सकते हैं। इस दवा के साथ शराब न पिएँ। अपने डॉक्टर को अपनी सभी दवाओं और बीमारियों के बारे में बताएँ, खासकर दिल, किडनी या लीवर की बीमारी हो तो। डॉक्टर की सलाह के बिना दवा अचानक बंद न करें।
💊 c-pride 25mg tablet Uses & Benefits
[{"condition":"Nausea and vomiting","description":"This medicine is used to prevent and treat nausea and vomiting by blocking dopamine D2 receptors in the brain's vomiting centre.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It helps relieve symptoms such as upper abdominal fullness, early satiety, bloating, and discomfort after meals by improving stomach emptying and reducing reflux.","evidence":"Well-established"},{"condition":"Diabetic gastroparesis","description":"This medicine improves delayed stomach emptying in people with diabetes by enhancing coordinated gastric contractions.","evidence":"Moderate"},{"condition":"Gastro-oesophageal reflux disease (GERD) as add-on therapy","description":"It may be added to standard acid-suppressing treatment to reduce regurgitation and improve gastric emptying in some patients.","evidence":"Limited"},{"condition":"Non-ulcer dyspepsia","description":"It is sometimes prescribed when no ulcer is found but the patient still has persistent indigestion-like symptoms.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Premature ejaculation","description":"Levosulpiride has been studied off-label for delaying ejaculation because of its effect on dopamine receptors, but it is not approved for this use.","evidence":"Limited"},{"condition":"Depression augmentation","description":"In some countries it has been used off-label as an add-on to antidepressants, but this is not a standard approved indication.","evidence":"Limited"}]
Primary treatment for: Functional dyspepsia and nausea/vomiting
Also treats: Diabetic gastroparesis, Gastro-oesophageal reflux disease, Non-ulcer dyspepsia
📋 Drug Information
| Generic Name(s) | Levosulpiride |
| Brand Name | Aurlev 75 Tablet |
| Manufacturer | Cause & Cure Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Atypical Antipsychotics |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the tablets in their original container, tightly closed. |
| Shelf Life | Typically 24 months from the date of manufacture, but always check the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Levosulpiride is a substituted benzamide that acts primarily as a selective antagonist at dopamine D2 receptors. In the brain, it blocks D2 receptors in the chemoreceptor trigger zone and the vomiting centre, which reduces nausea and vomiting. In the gastrointestinal tract, it enhances the release of acetylcholine from the myenteric plexus by blocking inhibitory dopamine D2 receptors, leading to stronger and more coordinated gastric and intestinal contractions. This dual action explains both its antiemetic effect and its prokinetic effect on the upper gut.
Mechanism Steps
💡 How to Take c-pride 25mg tablet
Strength: Levosulpiride 25mg immediate-release tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 25mg taken two to three times a day before meals, but the exact dose and frequency depend on the condition being treated, the severity of symptoms, and the patient's kidney and liver function. Some patients may need a lower dose if they have kidney or liver problems or if they are elderly. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and movement disorders. A lower starting dose may be advised, and kidney function should be checked before and during treatment. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no specific dose adjustment is usually required, but caution is advised. In severe kidney impairment, this medicine is contraindicated or should be used only under close specialist supervision with possible dose reduction. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no specific dose adjustment is usually required, but caution is advised. In severe liver impairment, this medicine is contraindicated or should be used only under close specialist supervision. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is generally 75mg to 150mg per day in divided doses, but this must be confirmed by the prescribing doctor. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of c-pride 25mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Metoclopramide | Major | |
| Haloperidol | Major | |
| Erythromycin | Major | |
| Levodopa | Major | |
| Amiodarone | Major | |
| Benzodiazepines | Moderate | |
| Opioids | Moderate | |
| Antihypertensives | Moderate | |
| Antacids | Minor | |
| Paracetamol | Minor |
🚨 Major Interactions
- Other dopamine antagonists (e.g., metoclopramide, antipsychotics)
- QT-prolonging drugs (e.g., erythromycin, amiodarone, haloperidol)
- Levodopa and other dopamine agonists
⚡ Moderate Interactions
- Antihypertensives
- Central nervous system depressants (e.g., benzodiazepines, opioids)
- Anticholinergic drugs
🍷 Alcohol Interaction
Do not drink alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of low blood pressure. It may also worsen movement-related side effects. If you drink alcohol regularly, discuss this with your doctor before starting this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to Levosulpiride or other benzamide medicines","Pheochromocytoma","Severe kidney impairment","Severe liver impairment","Epilepsy or seizure disorders","History of long QT syndrome or serious heart rhythm problems","Concurrent use with levodopa or dopamine agonists","Pregnancy and breastfeeding unless clearly advised by a doctor"]
⚠️ Warnings & Precautions
["This medicine can cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.","Do not drink alcohol while taking this medicine.","Use with caution in elderly patients, who may be more sensitive to side effects.","Use with caution in people with heart disease, electrolyte imbalance, or those taking other QT-prolonging medicines.","Tell your doctor if you have kidney or liver disease, as dose adjustment may be needed.","Do not stop this medicine suddenly without consulting your doctor, especially after long-term use.","Report any unusual muscle movements, high fever, or palpitations immediately.","Keep out of reach of children."]
🤱 Lactation Safety
Levosulpiride may pass into breast milk. Because it can affect dopamine levels and may suppress prolactin, it is generally not recommended during breastfeeding unless the doctor decides it is essential. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
If you suspect an overdose of this medicine, seek emergency medical care immediately. Overdose may cause severe drowsiness, dizziness, low blood pressure, abnormal heart rhythms, or uncontrolled muscle movements. Treatment is supportive and may include monitoring of vital signs, ECG, and electrolyte levels. There is no specific antidote. Do not try to induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, provided there is still a long time before your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as your doctor has prescribed, and do not increase or decrease the dose on your own. Swallow the tablet whole with a glass of water, preferably before meals, because taking it on an empty stomach helps it work better for nausea and stomach emptying. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not drink alcohol while taking this medicine, because alcohol can increase drowsiness and may worsen some side effects. Tell your doctor about all other medicines you take, especially medicines for heart rhythm problems, antidepressants, antipsychotics, and antibiotics such as erythromycin. If you have kidney or liver disease, your doctor may need to adjust the dose or monitor you more closely. Do not stop this medicine suddenly without talking to your doctor, especially if you have been taking it for a long time. Keep all follow-up appointments so your doctor can check your response and watch for any unwanted effects.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience drowsiness, dizziness, and movement disorders from this medicine. They may also have reduced kidney function, which can increase drug levels. A lower starting dose and close monitoring are advised. Regular review of the need for continued treatment is important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor before conception. The safety of Levosulpiride in pregnancy is not well established, and it should be used only if clearly needed. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used to treat nausea and vomiting or to improve stomach emptying. However, it can interact with other medicines used during surgery, such as anaesthetics and painkillers. Inform your surgeon and anaesthetist that you are taking this medicine.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental problems. Maintain good oral hygiene and stay hydrated. Inform your dentist that you are taking this medicine, especially if you are having surgery or procedures that require anaesthesia.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, so avoid strenuous exercise or activities that require high alertness until you know how it affects you. Light to moderate exercise such as walking is generally safe and can help digestion. If you feel dizzy or weak during exercise, stop and rest.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, which may affect your ability to drive, operate machinery, or perform tasks that require concentration. It is best to avoid these activities until you know how the medicine affects you. Most people can continue their usual desk work, but if your job involves safety-sensitive tasks, discuss with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your symptoms and response. If you experience serious side effects such as uncontrolled movements, palpitations, or high fever with muscle stiffness, stop the medicine and seek medical help immediately. For planned discontinuation, your doctor may reduce the dose gradually.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of movement disorders such as tardive dyskinesia and extrapyramidal symptoms, as well as raised prolactin levels leading to breast changes or menstrual irregularities. Rarely, it can affect heart rhythm. Regular review by your doctor is important, and the lowest effective dose should be used for the shortest possible time. Do not continue this medicine for months without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent, low-fat meals can reduce symptoms of dyspepsia and gastroparesis.
Evidence: Well-establishedRelaxation techniques and counselling can help reduce functional gastrointestinal symptoms.
Evidence: ModerateDomperidone, metoclopramide, or itopride may be alternatives depending on the condition and patient factors.
Evidence: Well-establishedSome studies suggest acupuncture may help with functional dyspepsia, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive routine vaccinations while taking this medicine unless your doctor advises otherwise.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the label intact
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a doctor's letter, especially for international travel, as some countries may have restrictions on certain medicines. Store the tablets in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Do not pack it in checked luggage; keep it in your hand baggage. Check customs rules of your destination before travelling.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts reducing nausea within 30 to 60 minutes after a dose. Improvement in fullness and bloating may take a few days of regular use.
A: It is best taken before meals, as food may slightly delay absorption. Follow your doctor's instructions about timing.
A: If you remember soon after the missed dose, take it. If it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not double dose.
A: Long-term use should be under medical supervision because of the risk of movement disorders and raised prolactin levels. Your doctor will decide how long you need it.
A: No, alcohol should be avoided because it increases drowsiness, dizziness, and other side effects.
A: The safety of this medicine during pregnancy is not well established. It should be used only if your doctor decides the benefit clearly outweighs the risk.
🤔 Common Patient Concerns
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Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller. It is used for nausea, vomiting, and stomach emptying problems. - Myth: This medicine can be taken for any stomach upset.
Fact: This medicine is prescribed for specific conditions such as functional dyspepsia and gastroparesis. It is not for ordinary indigestion or gas. - Myth: More dose means faster relief.
Fact: Taking more than the prescribed dose does not give faster relief and can increase the risk of serious side effects. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol should be avoided because it increases drowsiness, dizziness, and other side effects.
🔄 Alternative Options
Generic Alternatives
- Levosulpiride 25mg tablet (generic)
Brand Alternatives
- Avopride 25mg tablet