btc kit - Fluconazole (150mg) + Azithromycin (1000mg) medicine

btc kit - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Lincoln Pharmaceuticals Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is btc kit used for?

Azithral XP 150mg/1000mg/1000mg Tablet (Fluconazole + Azithromycin) is used to treat GYNAECOLOGICAL. It contains Fluconazole (150mg) + Azithromycin (1000mg), which Fluconazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing ergoste. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Fluconazole + Azithromycin
  • Manufacturer: Lincoln Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š btc kit Uses & Benefits

Treatment of vaginal candidiasis with concurrent bacterial vaginosis or cervicitis; mixed gynecological infections.

Off-label uses: Treatment of pelvic inflammatory disease (PID) when fungal co-infection suspected.

๐Ÿ“‹ Drug Information

Generic Name(s)Fluconazole + Azithromycin
Brand NameAzithral XP 150mg/1000mg/1000mg Tablet
ManufacturerLincoln Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassAntifungal + Antibiotic
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; azithromycin absorption is rapid, fluconazole absorption is almost complete.
DistributionWidely distributed into tissues and fluids; azithromycin concentrates intracellularly, fluconazole penetrates CSF.
Protein BindingFluconazole: 11-12%; Azithromycin: 7-50% (concentration-dependent).
MetabolismFluconazole: minimally hepatic (CYP2C9, CYP3A4); Azithromycin: not extensively metabolized.
Half-LifeFluconazole: ~30 hours; Azithromycin: ~68 hours (terminal).
ExcretionFluconazole: primarily renal (80% unchanged); Azithromycin: primarily biliary/fecal.
BioavailabilityFluconazole: >90%; Azithromycin: ~37% (oral).
Onset of ActionFluconazole: 1-2 hours; Azithromycin: 2-3 hours.
Peak Plasma TimeFluconazole: 1-2 hours; Azithromycin: 2-3 hours.
Duration of ActionFluconazole: 24-48 hours; Azithromycin: up to 24 hours.

How It Works

Fluconazole inhibits fungal cytochrome P450 14ฮฑ-demethylase, preventing ergosterol synthesis; Azithromycin binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis.

Mechanism Steps

1Fluconazole selectively inhibits fungal cytochrome P450 14ฮฑ-demethylase, blocking conversion of lanosterol to ergosterol.
2Depletion of ergosterol disrupts fungal cell membrane integrity and function.
3Azithromycin binds to the 50S ribosomal subunit of bacteria, inhibiting translocation of peptides.

๐Ÿ’ก How to Take btc kit

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of btc kit

โœ… Common Side Effects

  • Nausea
  • Diarrhea
  • Abdominal pain
  • Headache
  • Vaginal discharge

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Hepatotoxicity
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Thrombocytopenia
  • Pancreatitis
  • Hearing loss
  • Tinnitus

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased INR and bleeding risk
Cisapride Major Risk of cardiac arrhythmias
Terfenadine Major Risk of QT prolongation
Astemizole Major Risk of QT prolongation
Pimozide Major Risk of cardiac toxicity
Quinidine Major Risk of QT prolongation
Ergotamine Major Risk of ergotism
Oral hypoglycemics Moderate Increased hypoglycemic effect
Phenytoin Moderate Increased phenytoin levels
Rifampin Moderate Decreased fluconazole levels
Cyclosporine Moderate Increased cyclosporine levels
Theophylline Moderate Increased theophylline levels
Digoxin Moderate Increased digoxin levels
Oral contraceptives Minor Possible reduced efficacy
Antacids Minor Reduced azithromycin absorption
H2 antagonists Minor Reduced azithromycin absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Cisapride
  • Terfenadine
  • Astemizole
  • Pimozide
  • Quinidine
  • Ergotamine

โšก Moderate Interactions

  • Oral hypoglycemics
  • Phenytoin
  • Rifampin
  • Cyclosporine
  • Theophylline
  • Digoxin

โ„น๏ธ Minor Interactions

  • Oral contraceptives
  • Antacids
  • H2 antagonists

๐Ÿฝ๏ธ Food Interactions

Azithromycin absorption may be reduced with food; fluconazole unaffected.

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to azithromycin, fluconazole, or other azoles; concurrent use with cisapride, terfenadine, astemizole, pimozide, quinidine, ergotamine.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, ECG (if risk factors), signs of superinfection.

๐Ÿคฑ Lactation Safety

Fluconazole and azithromycin are excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Supportive care; gastric lavage if recent; monitor ECG for QT prolongation; hemodialysis may remove fluconazole.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

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