brumol kid 100 mg/125 mg tablet - Ibuprofen (100mg) + Paracetamol (125mg) medicine

Acefen 100 mg/125 mg Tablet: Complete Medicine Guide

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🏭 Southshourne Corporation India 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Consult your doctor before use, especially in the third trimester. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for short-term pain and fever relief.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
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When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is brumol kid 100 mg/125 mg tablet used for?

This medicine is a combination of Ibuprofen 100 mg and Paracetamol 125 mg used for short-term relief of mild to moderate pain and fever. It works by reducing pain and inflammation. Take it with food and do not exceed 6 tablets in 24 hours.

  • Generic Name: Ibuprofen + Paracetamol
  • Manufacturer: Southshourne Corporation India
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 brumol kid 100 mg/125 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा इबुप्रोफेन 100 मिलीग्राम और पैरासिटामोल 125 मिलीग्राम का संयोजन है। इसका उपयोग हल्के से मध्यम दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों में दर्द, मासिक धर्म में ऐंठन और सर्दी-जुकाम से जुड़े बुखार में राहत देती है। इसे भोजन के साथ लें और 24 घंटे में 6 गोलियों से अधिक न लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, चक्कर आना और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन पेट में रक्तस्राव, गुर्दे की समस्या, एलर्जी प्रतिक्रिया और लीवर की क्षति हो सकती है। यदि काला मल, खून की उल्टी, गंभीर पेट दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या आंखों या त्वचा का पीलापन दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन या दूध के साथ लें ताकि पेट की परेशानी कम हो। खाली पेट न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे पेट में रक्तस्राव और लीवर की क्षति का खतरा बढ़ जाता है। पैरासिटामोल या इबुप्रोफेन युक्त अन्य दवाएं बिना डॉक्टर की सलाह के न लें। यदि आपको गुर्दे की बीमारी, लीवर की बीमारी, हृदय की विफलता या अस्थमा है तो डॉक्टर को बताएं। बुखार के लिए 3 दिन से अधिक और दर्द के लिए 10 दिन से अधिक इस दवा का उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 brumol kid 100 mg/125 mg tablet Uses & Benefits

[{"condition":"Mild to moderate pain","description":"Relieves pain from headache, toothache, muscle ache, back pain, and menstrual cramps.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces fever associated with common cold, flu, or other infections.","evidence":"Well-established"},{"condition":"Inflammatory conditions","description":"Helps reduce pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling in conditions like arthritis, sprains, and strains.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Post-operative pain","description":"May be used off-label for short-term post-operative pain management under medical supervision.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Toothache, Muscle ache, Menstrual cramps, Arthritis, Cold and flu

📋 Drug Information

Generic Name(s)Ibuprofen + Paracetamol
Brand NameAdiflam Plus 400 mg/500 mg Tablet
ManufacturerSouthshourne Corporation India
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNonsteroidal Anti-inflammatory Drug (NSAID) + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore below 30°C in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce stomach upset.
2
Do not exceed 6 tablets in 24 hours.
3
Avoid alcohol while taking this medicine.
4
Do not use for more than 3 days for fever or 10 days for pain without medical advice.
5
Consult your doctor if you have kidney disease, liver disease, heart failure, or asthma.
6
Report any unusual bleeding or bruising immediately.
7
Do not take other medicines containing paracetamol or ibuprofen without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Headache
This medicine is commonly prescribed for this.
Likely Use
✅
Fever
This medicine is used to reduce fever.
Likely Use
✅
Toothache
This medicine can relieve toothache.
Likely Use
✅
Muscle ache
This medicine helps with muscle pain.
Likely Use
✅
Menstrual cramps
This medicine is effective for menstrual pain.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIbuprofen is rapidly absorbed from the gastrointestinal tract after oral administration. Paracetamol is also rapidly and almost completely absorbed from the small intestine. Food may delay the absorption of both drugs but does not significantly reduce the extent of absorption.
DistributionIbuprofen is highly bound to plasma proteins and distributes into synovial fluid, breast milk, and across the placenta. Paracetamol distributes widely into most body tissues and fluids, with a volume of distribution of about 0.9 L/kg.
Protein BindingIbuprofen is approximately 99% bound to plasma proteins. Paracetamol is only about 10-25% bound to plasma proteins.
MetabolismIbuprofen is metabolized in the liver by CYP2C9 to inactive metabolites. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation; a small fraction is metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of ibuprofen is about 2 hours. The elimination half-life of paracetamol is about 2-3 hours.
ExcretionIbuprofen metabolites are excreted mainly in the urine. Paracetamol metabolites are excreted in the urine, with about 90% of the dose excreted within 24 hours.
BioavailabilityIbuprofen oral bioavailability is approximately 80-90%. Paracetamol oral bioavailability is approximately 80-100%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations of ibuprofen occur about 1-2 hours after oral administration. Paracetamol peaks about 30-60 minutes after oral administration.
Duration of ActionPain relief and fever reduction last about 4-6 hours.

How It Works

This medicine combines two active ingredients with different mechanisms. Ibuprofen is a non-steroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing the production of prostaglandins which are mediators of pain, inflammation, and fever. Paracetamol acts mainly in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis. Together they provide additive pain relief and fever reduction.

Mechanism Steps

1
Ibuprofen inhibits COX enzymes: Ibuprofen binds reversibly to COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This leads to decreased levels of prostaglandins, which are responsible for pain, inflammation, and fever.
3
Paracetamol acts centrally: Paracetamol inhibits prostaglandin synthesis in the brain and may activate descending inhibitory pathways, reducing pain perception and fever.
4
Additive analgesic and antipyretic effect: The combined actions of ibuprofen and paracetamol produce greater pain relief and fever reduction than either alone.

💡 How to Take brumol kid 100 mg/125 mg tablet

Strength: Tablet containing Ibuprofen 100 mg and Paracetamol 125 mg.

1Take this medicine by mouth with a full glass of water.
2Take it with food or milk to reduce stomach upset.
3Swallow the tablet whole. Do not crush or chew.
4Take it at the same times each day if prescribed regularly.
5Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 1-2 tablets every 4-6 hours as needed for pain or fever. Do not exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use the lowest effective dose for the shortest duration. Consult your doctor for dose adjustment.
Renal ImpairmentUse with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseDo not exceed 6 tablets in 24 hours.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of stomach bleeding and liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of brumol kid 100 mg/125 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk. If nausea persists, consult your doctor.
Stomach pain or heartburn (Common (5-10%))
Take with food. Avoid alcohol. If severe, consult your doctor.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.
Headache (Uncommon (1-5%))
Usually resolves on its own. If persistent, consult your doctor.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Liver damage (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe fatigue.
Kidney problems (Rare (<0.1%))
Seek medical attention if you notice decreased urine output, swelling, or confusion.
Severe allergic reaction (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, or throat, difficulty breathing, or rash.

⚠️ Rare Side Effects

Severe skin reactions such as Stevens-Johnson syndrome
Aseptic meningitis
Pancreatitis
Hepatitis
Acute renal failure

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
ACE inhibitors Major
Corticosteroids Moderate
Diuretics Moderate
SSRIs Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • ACE inhibitors and ARBs

⚡ Moderate Interactions

  • Corticosteroids
  • Diuretics
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding from ibuprofen and liver damage from paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active stomach ulcer or history of recurrent ulcers","Severe kidney disease","Severe liver disease","Asthma triggered by aspirin or other NSAIDs","Allergy to ibuprofen, paracetamol, or any ingredient","Third trimester of pregnancy","Children under 12 years"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Do not exceed the recommended dose.","Do not use for more than 3 days for fever or 10 days for pain without medical advice.","Avoid alcohol while taking this medicine.","Consult your doctor if you have kidney disease, liver disease, heart failure, or asthma.","Do not take other medicines containing paracetamol or ibuprofen without consulting your doctor.","Stop use and consult your doctor if you experience severe stomach pain, black stools, or vomiting blood."]

🤱 Lactation Safety

Ibuprofen and paracetamol are considered compatible with breastfeeding in usual doses. However, consult your doctor before use.

💊 Overdose Management

Overdose can cause severe liver damage from paracetamol and kidney damage from ibuprofen. Seek immediate medical attention. Treatment includes activated charcoal, acetylcysteine for paracetamol toxicity, and supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Always take this medicine with food or a glass of milk to protect your stomach. Do not take it on an empty stomach. Do not drink alcohol while taking this medicine because it increases the risk of stomach bleeding and liver damage. Do not take other medicines containing paracetamol or ibuprofen without asking your doctor, as this can lead to overdose. If you have kidney disease, liver disease, heart failure, or asthma, tell your doctor before taking this medicine. Do not use this medicine for more than 3 days for fever or 10 days for pain unless your doctor advises otherwise. Keep out of reach of children. Store below 30°C in a dry place.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy or are pregnant. Avoid use in the third trimester.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may increase bleeding risk and interact with other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Stay well hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have pain or fever. Rest and gentle movement are recommended until symptoms improve.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed food intake.
Stay well hydrated.
Avoid alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve after 3 days for fever or 10 days for pain, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, and liver damage. It should only be used short-term unless prescribed by a doctor. Regular monitoring of liver and kidney function may be required with prolonged use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Hot and cold compresses

Can help relieve localized pain and inflammation.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it below 30°C and away from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with menstrual cramps
She took this medicine as prescribed for menstrual pain. She noticed relief within 45 minutes. She made sure to take it with food to avoid stomach upset.
💡 Lesson: Taking this medicine with food improves tolerability and ensures better pain relief.
👤 A 50-year-old man with fever and body ache
He took this medicine for fever and body ache. His fever reduced within an hour. He was advised not to take it for more than 3 days without consulting a doctor.
💡 Lesson: Short-term use is safe, but persistent fever requires medical evaluation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30-60 minutes after taking this medicine.

Q: Can I take it on an empty stomach?

A: No, it should be taken with food or milk to reduce stomach upset.

Q: Is it safe for children?

A: This medicine is not recommended for children under 12 years without medical advice.

Q: Can I take it with other painkillers?

A: Do not take other medicines containing paracetamol or ibuprofen without consulting your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for brumol kid 100 mg/125 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken on an empty stomach.
    Fact: It should be taken with food or milk to reduce stomach upset.
  • Myth: It is safe to take this medicine for long periods without medical advice.
    Fact: It should only be used short-term unless prescribed by a doctor.

🔄 Alternative Options

Generic Alternatives

  • Ibuprofen 100 mg + Paracetamol 125 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ibuprofen 100 mg + Paracetamol 125 mg","strength":"Low dose","use":"Mild pain and fever"},{"medicine":"Ibuprofen 200 mg + Paracetamol 325 mg","composition":"Ibuprofen 200 mg + Paracetamol 325 mg","strength":"Moderate dose","use":"Moderate pain and fever"}]

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