alcef lb 100 tablet - Cefixime (100mg) + Lactobacillus (2.5Million Spores) medicine

Alcef LB 100 Tablet: A Comprehensive Guide

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🏭 Southshourne Corporation India 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe, persistent diarrhea or bloody stools
  • Rash, itching, or swelling of the face, lips, or throat
  • Difficulty breathing or swallowing
  • Yellowing of the skin or eyes
  • Decreased urine output or swelling in the legs
  • Unusual bleeding or bruising
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is alcef lb 100 tablet used for?

This medicine is a combination antibiotic and probiotic used to treat bacterial infections such as urinary tract infections, respiratory tract infections, and gonorrhea. It works by killing bacteria and helping maintain gut health.

  • Generic Name: Cefixime (100mg) + Lactobacillus (2.5Million Spores)
  • Manufacturer: Southshourne Corporation India
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alcef lb 100 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफिक्सिम और लैक्टोबैसिलस का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमणों जैसे मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण और गोनोरिया के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर संक्रमण को रोकती है और आंतों में अच्छे बैक्टीरिया को बनाए रखने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको गंभीर दस्त, एलर्जी, या त्वचा पर चकत्ते दिखाई दें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। इसे भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। एंटासिड या आयरन सप्लीमेंट के साथ इस दवा को न लें, कम से कम 2 घंटे का अंतराल रखें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alcef lb 100 tablet Uses & Benefits

[{"condition":"Uncomplicated urinary tract infections","description":"This medicine is used to treat bacterial infections of the urinary tract caused by susceptible organisms such as Escherichia coli and Klebsiella pneumoniae.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"It is effective against bacterial bronchitis, pharyngitis, and tonsillitis caused by susceptible strains of Streptococcus pneumoniae and Haemophilus influenzae.","evidence":"Well-established"},{"condition":"Uncomplicated gonorrhea","description":"This medicine is indicated for the treatment of uncomplicated urethral, cervical, or rectal gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"},{"condition":"Otitis media","description":"It may be used to treat middle ear infections in children caused by susceptible bacteria, though other antibiotics are often preferred.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for severe traveler's diarrhea caused by susceptible bacteria, but not routinely recommended.","evidence":"Limited"},{"condition":"Prophylaxis in dental procedures","description":"Rarely used off-label for prevention of infective endocarditis in high-risk patients undergoing dental procedures, but not a standard recommendation.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Gonorrhea, Otitis media

📋 Drug Information

Generic Name(s)Cefixime (100mg) + Lactobacillus (2.5Million Spores)
Brand Namealcef lb 100 tablet
ManufacturerSouthshourne Corporation India
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always complete the full prescribed course of this medicine, even if symptoms improve early, to prevent antibiotic resistance.
2
Take this medicine with food to reduce the risk of stomach upset and diarrhea.
3
Avoid taking antacids or iron supplements within two hours of this medicine, as they can reduce its absorption.
4
Inform your doctor if you have kidney or liver problems, as dose adjustment may be needed.
5
Report any severe or persistent diarrhea, skin rash, or signs of allergic reaction immediately.
6
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning sensation during urination
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Fever with cough and phlegm
This medicine may be used for bacterial respiratory infections.
Likely Use
❌
Runny nose and sneezing
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract after oral administration. The absolute bioavailability of cefixime is approximately 40% to 50% and is not significantly affected by food. Lactobacillus spores are resistant to gastric acid and reach the intestines where they germinate.
DistributionCefixime distributes widely into body tissues and fluids, including the respiratory tract, urinary tract, and bile. It does not significantly penetrate the cerebrospinal fluid in the absence of inflammation. Lactobacillus remains primarily in the gastrointestinal tract.
Protein BindingCefixime is approximately 65% bound to plasma proteins, primarily albumin.
MetabolismCefixime is not significantly metabolized in the body. It is excreted largely unchanged.
Half-LifeThe elimination half-life of cefixime is approximately 3 to 4 hours in healthy adults with normal renal function.
ExcretionCefixime is excreted primarily unchanged in the urine, with about 50% of an oral dose recovered in the urine within 24 hours. Lactobacillus is excreted in the feces.
BioavailabilityThe absolute bioavailability of cefixime is approximately 40% to 50%.
Onset of ActionThe onset of action for cefixime is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations of cefixime are achieved approximately 2 to 4 hours after oral administration.
Duration of ActionThe duration of action for cefixime is approximately 12 to 24 hours, depending on the dose and the susceptibility of the bacteria.

How It Works

Cefixime, the antibiotic component of this medicine, works by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final transpeptidation step of peptidoglycan synthesis, which is essential for the structural integrity of the bacterial cell wall. As a result, the bacterial cell wall becomes weakened and the cell undergoes lysis and death. Lactobacillus, the probiotic component, helps to restore and maintain the natural balance of beneficial bacteria in the gastrointestinal tract, which can be disrupted by antibiotic therapy. This combination aims to treat the infection while reducing the risk of antibiotic-associated diarrhea.

Mechanism Steps

1
Binding to penicillin-binding proteins: Cefixime binds to specific penicillin-binding proteins (PBPs) on the inner membrane of the bacterial cell wall.
2
Inhibition of cell wall synthesis: This binding inhibits the transpeptidation reaction that cross-links peptidoglycan chains, which are essential for cell wall strength.
3
Bacterial cell lysis: Without a proper cell wall, the bacterial cell cannot maintain its shape and internal pressure, leading to cell lysis and death.
4
Probiotic effect of lactobacillus: Lactobacillus colonizes the gut and helps restore the natural balance of beneficial bacteria, potentially reducing antibiotic-associated diarrhea.

💡 How to Take alcef lb 100 tablet

Strength: Cefixime 100 mg + Lactobacillus 2.5 million spores immediate-release tablet

1Take this medicine orally with a full glass of water.
2You may take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed by your doctor.
5Complete the full course of therapy, even if you feel better after a few days.
6Do not take antacids or iron supplements within 2 hours of this medicine.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200 mg to 400 mg per day, taken as a single dose or in two divided doses, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a common dose is 200 mg twice daily or 400 mg once daily. For uncomplicated gonorrhea, a single 400 mg dose is often used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Dose must be individualized by a qualified clinician based on renal function.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) 20-40 mL/min, the dose should be reduced to 200 mg once daily. For CrCl less than 20 mL/min, the dose should be reduced to 200 mg every 48 hours or as directed by a physician. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is recommended for patients with hepatic impairment, but caution is advised. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Antacids
Avoid within 2 hours
May reduce absorption of cefixime.
Iron supplements
Avoid within 2 hours
May reduce absorption of cefixime.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alcef lb 100 tablet

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe or persistent, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.

🚨 Serious Side Effects

Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe, persistent diarrhea, abdominal cramps, or fever.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience rash, itching, swelling of face/lips/throat, difficulty breathing, or dizziness.
Stevens-Johnson syndrome (Very rare (<0.01%))
Seek immediate medical attention if you develop skin rash, blisters, or peeling skin with fever.
Liver enzyme abnormalities (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention if seizures occur.
Blood dyscrasias (e.g., thrombocytopenia, leukopenia)
Report unusual bleeding, bruising, or signs of infection to your doctor.
Interstitial nephritis
Report decreased urine output, swelling, or fatigue to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Antacids Moderate
Iron supplements Moderate
Probenecid Moderate
Oral contraceptives Minor
Loop diuretics Minor

🚨 Major Interactions

  • Warfarin
  • Carbamazepine

⚡ Moderate Interactions

  • Antacids (aluminum or magnesium hydroxide)
  • Iron supplements
  • Probenecid

🍷 Alcohol Interaction

Alcohol does not directly interact with cefixime, but it may worsen gastrointestinal side effects such as nausea and abdominal pain. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cefixime or other cephalosporin antibiotics","History of severe allergic reaction to penicillin","Porphyria","Severe renal impairment without dose adjustment"]

⚠️ Warnings & Precautions

["Serious allergic reactions, including anaphylaxis, can occur. Discontinue and seek immediate medical help if signs occur.","Clostridioides difficile-associated diarrhea can occur. Report severe or persistent diarrhea.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","Dose adjustment is required in patients with renal impairment.","Prolonged use may lead to overgrowth of non-susceptible organisms.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Cefixime is excreted in human breast milk in low concentrations. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks. Monitor the infant for diarrhea or thrush.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, abdominal pain, and diarrhea. There is no specific antidote. Treatment is symptomatic and supportive. In case of overdose, contact a poison control center or emergency room immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better. Take the tablet with a full glass of water, preferably with food to reduce stomach upset. Avoid taking antacids or iron supplements within two hours of this medicine, as they can reduce its absorption. Inform your doctor if you have kidney problems, a history of gastrointestinal disease, or if you are pregnant or breastfeeding. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and may require dose adjustment. Monitor renal function closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe but should be used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out bacteria.
🥗
Maintain good hygiene, especially handwashing, to prevent reinfection.
😴
Include probiotic-rich foods like yogurt in your diet to support gut health.
💧
Get adequate rest to help your body fight the infection.
🧘
Avoid sharing personal items like towels to prevent the spread of infection.

🏋️ Exercise Considerations

This medicine may cause dizziness in some people. Avoid strenuous exercise or driving if you feel dizzy. Otherwise, light to moderate exercise is generally safe.

🥗 Diet Recommendations

Drink plenty of water throughout the day.
Eat a balanced diet rich in fruits and vegetables.
Include yogurt or other probiotic foods to help maintain gut flora.
Avoid spicy and oily foods if you experience stomach upset.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or headache in some individuals. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it should not significantly impact your daily activities.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Complete the full prescribed course. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance and superinfection. Regular monitoring of renal and hepatic function may be required if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotic supplements

Can help maintain gut health during antibiotic therapy.

Evidence: Well-established
Increased fluid intake

Helps flush out bacteria in urinary tract infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines like the typhoid vaccine. Consult your doctor for timing of vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Keep it in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it with food as advised and completed the 7-day course. Her symptoms improved within 3 days, and she experienced only mild nausea that resolved after the first few doses.
💡 Lesson: Taking the medicine with food and completing the full course led to a successful outcome with minimal side effects.
👤 A 45-year-old man with bronchitis
He was prescribed this medicine for bacterial bronchitis. He initially felt better after 4 days and wanted to stop, but his doctor advised him to complete the 10-day course. He did so and recovered fully without recurrence.
💡 Lesson: Stopping antibiotics early can lead to relapse and resistance. Always complete the prescribed course.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: It is classified as Pregnancy Category B. Consult your doctor before taking it if you are pregnant or planning to become pregnant.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may worsen side effects like nausea and abdominal pain.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: Probiotics in antibiotics are unnecessary.
    Fact: The lactobacillus in this medicine helps restore beneficial gut bacteria and may reduce antibiotic-associated diarrhea.

🔄 Alternative Options

Generic Alternatives

  • Cefixime 100 mg + Lactobacillus 2.5 million spores tablet

Brand Alternatives

  • Alcef LB 100 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cefixime 100 mg + Lactobacillus 2.5M spores","strength":"100 mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Cefixime 200 mg + Lactobacillus","composition":"Cefixime 200 mg + Lactobacillus 2.5M spores","strength":"200 mg","dosage_form":"Tablet","route":"Oral"}]

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