alcef lb 200 tablet - Cefixime (200mg) + Lactobacillus (2.5Million spores) medicine

Alcef LB 200 Tablet: Comprehensive Medicine Guide

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🏭 Southshourne Corporation India 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe watery diarrhea or diarrhea with fever and abdominal cramps
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or wheezing
  • Widespread rash, blistering, or peeling of the skin
  • Unusual bleeding or bruising
  • Decreased urine output or swelling in the legs
  • Yellowing of the skin or eyes
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is alcef lb 200 tablet used for?

This medicine is a combination of cefixime, an antibiotic, and lactobacillus, a probiotic. It is used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and ear infections. The antibiotic kills bacteria, while the probiotic helps protect gut health.

  • Generic Name: Cefixime + Lactobacillus
  • Manufacturer: Southshourne Corporation India
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alcef lb 200 tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफिक्सिम और लैक्टोबैसिलस का संयोजन है। यह बैक्टीरियल संक्रमण जैसे श्वसन तंत्र संक्रमण, मूत्र मार्ग संक्रमण और कान के संक्रमण के इलाज के लिए इस्तेमाल की जाती है। सेफिक्सिम बैक्टीरिया को मारता है और लैक्टोबैसिलस पेट के अच्छे बैक्टीरिया की रक्षा करता है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त या त्वचा पर चकत्ते हो सकते हैं। अगर कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को भोजन के साथ या बिना भोजन के ले सकते हैं। एंटासिड या आयरन सप्लीमेंट के साथ लेने से बचें। यदि आपको गंभीर दस्त, चकत्ते या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 alcef lb 200 tablet Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat bacterial bronchitis, pharyngitis, and tonsillitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Ear infections","description":"Prescribed for acute otitis media caused by susceptible bacteria like Haemophilus influenzae and Moraxella catarrhalis.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Used as a single-dose treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"},{"condition":"Prophylaxis in dental procedures","description":"Rarely used off-label for prevention of infective endocarditis in high-risk patients undergoing dental procedures, but not a standard recommendation.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Ear infections, Gonorrhea

📋 Drug Information

Generic Name(s)Cefixime + Lactobacillus
Brand NameAfix 200mg Tablet
ManufacturerSouthshourne Corporation India
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassThird-generation cephalosporin antibiotic + Probiotic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always complete the full prescribed course of this medicine, even if you start feeling better after a few days.
2
Take this medicine with food if it causes stomach upset.
3
Separate this medicine from antacids or iron supplements by at least 2 hours to ensure proper absorption.
4
Inform your doctor if you have kidney disease, as dose adjustment may be needed.
5
Watch for severe diarrhea, which could be a sign of a serious gut infection, and report it to your doctor immediately.
6
Do not use this medicine to treat viral infections like the common cold or flu.
7
If you are on oral contraceptives, use a backup method during and for 7 days after treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Urinary tract infection symptoms (burning urination, frequent urination)
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Respiratory tract infection symptoms (cough, fever, chest congestion)
This medicine is used for bacterial respiratory infections.
Likely Use
✅
Ear pain or discharge
This medicine is effective for bacterial ear infections.
Likely Use
❌
Common cold or flu
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract after oral administration. The presence of food does not significantly affect the extent of absorption, but it may slightly delay the time to peak concentration. The lactobacillus spores are resistant to stomach acid and reach the intestines where they germinate and become active.
DistributionCefixime distributes well into various body tissues and fluids, including the respiratory tract, urinary tract, and middle ear fluid. It does not penetrate the cerebrospinal fluid in significant amounts when the meninges are not inflamed. Lactobacillus remains primarily in the gastrointestinal tract and does not distribute systemically.
Protein BindingCefixime is approximately 65% bound to plasma proteins, primarily albumin. Lactobacillus does not bind to plasma proteins as it acts locally in the gut.
MetabolismCefixime is not significantly metabolized in the body and is excreted largely unchanged. Lactobacillus is not metabolized in the conventional sense; it acts locally in the intestines.
Half-LifeThe elimination half-life of cefixime is approximately 3 to 4 hours in healthy adults with normal kidney function. It may be prolonged in patients with renal impairment.
ExcretionCefixime is primarily excreted unchanged in the urine, with about 50% of an oral dose recovered in the urine within 24 hours. Lactobacillus is excreted in the feces as part of the natural gut flora.
BioavailabilityThe oral bioavailability of cefixime is approximately 40% to 50% when taken with or without food. The lactobacillus spores are designed to survive stomach acid and reach the intestines, but their bioavailability is not measured in the same way as systemic drugs.
Onset of ActionCefixime begins to kill susceptible bacteria within a few hours after the first dose, but noticeable improvement in symptoms of infection usually occurs within 24 to 48 hours. Lactobacillus may start to exert its probiotic effects within a few days of regular use.
Peak Plasma TimePeak plasma concentrations of cefixime are reached approximately 3 to 4 hours after oral administration. The lactobacillus component does not have a measurable plasma peak as it acts locally.
Duration of ActionThe antibacterial effect of cefixime lasts for about 12 to 24 hours after a dose, depending on the susceptibility of the bacteria and the site of infection. Lactobacillus provides ongoing support to gut flora as long as it is taken regularly.

How It Works

Cefixime, the antibiotic component of this medicine, works by binding to specific penicillin-binding proteins inside the bacterial cell wall. This binding inhibits the final step of peptidoglycan synthesis, which is essential for the strength and structure of the bacterial cell wall. As a result, the bacterial cell wall becomes weak and the bacterium eventually dies. Cefixime is bactericidal, meaning it kills bacteria directly. The lactobacillus component is a probiotic that helps maintain the natural balance of beneficial bacteria in the intestines, which can be disrupted by antibiotic therapy. Lactobacillus does not have antibacterial action against the infection itself but supports gut health during treatment.

Mechanism Steps

1
Binding to penicillin-binding proteins: Cefixime binds to specific penicillin-binding proteins located inside the bacterial cell wall.
2
Inhibition of cell wall synthesis: This binding blocks the cross-linking of peptidoglycan chains, which are essential for the bacterial cell wall structure.
3
Bacterial cell lysis: Without a proper cell wall, the bacterium cannot maintain its shape and internal pressure, leading to cell rupture and death.
4
Probiotic support: Lactobacillus colonizes the gut and produces lactic acid, which helps suppress harmful bacteria and restore the natural balance of intestinal flora.

💡 How to Take alcef lb 200 tablet

Strength: Each tablet contains Cefixime 200 mg and Lactobacillus 2.5 million spores.

1Take the tablet with a full glass of water.
2You can take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same time each day to maintain consistent levels.
5If you are also taking antacids or iron supplements, take them at least 2 hours apart from this medicine.
6Do not skip doses or stop the course early.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200 mg to 400 mg per day, taken as a single daily dose or divided into two doses every 12 hours, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a common dose is 200 mg twice daily or 400 mg once daily. For respiratory tract infections, 200 mg twice daily is often used. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription exactly.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may have reduced kidney function, which can affect the elimination of cefixime. Dose adjustment may be necessary based on renal function. Consult your doctor for personalized dosing.
Renal ImpairmentIn patients with renal impairment, the dose of cefixime may need to be reduced. For creatinine clearance between 20 and 40 mL/min, a dose of 200 mg once daily is often recommended. For creatinine clearance less than 20 mL/min, a dose of 200 mg every 48 hours or as directed by a doctor. Always consult a healthcare provider for dose adjustment.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment, as cefixime is not significantly metabolized by the liver. However, caution is advised in patients with both hepatic and renal impairment.
Maximum Daily DoseThe maximum recommended daily dose of cefixime is 400 mg. Do not exceed this dose unless directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Antacids
Avoid taking together
Reduces absorption of cefixime. Separate by 2 hours.
Iron supplements
Avoid taking together
Reduces absorption of cefixime. Separate by 2 hours.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of alcef lb 200 tablet

✅ Common Side Effects

Loose stools or mild diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. If diarrhea persists or becomes severe, consult your doctor.
Nausea (Common (5-10%))
Take the tablet with food to reduce nausea. If it continues, talk to your doctor.
Stomach pain or cramps (Common (5-10%))
Try taking the medicine with a meal. If pain is severe or persistent, seek medical advice.
Headache (Uncommon (1-5%))
Rest and stay hydrated. Consult your doctor if headache is severe or does not go away.
Mild skin rash (Uncommon (1-5%))
Monitor the rash. If it spreads or is accompanied by itching or swelling, contact your doctor immediately.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a widespread rash.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe watery diarrhea, fever, or abdominal cramps that do not improve.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek immediate medical attention if you notice a painful rash, blistering, or peeling of the skin.
Blood disorders (e.g., low platelet count) (Very rare (<0.01%))
Report any unusual bleeding or bruising to your doctor promptly.
Kidney problems (e.g., interstitial nephritis) (Very rare (<0.01%))
Inform your doctor if you notice decreased urine output or swelling in your legs.

⚠️ Rare Side Effects

Liver enzyme elevation
Your doctor may monitor liver function if you have risk factors. Report yellowing of eyes or skin.
Seizures
Seek immediate medical attention if seizures occur, especially in patients with kidney disease.
Hemolytic anemia
Report unusual tiredness, pale skin, or shortness of breath to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Carbamazepine Major
Antacids Moderate
Iron supplements Moderate
Probenecid Moderate
Oral contraceptives Minor
Live bacterial vaccines Minor

🚨 Major Interactions

  • Warfarin
  • Carbamazepine

⚡ Moderate Interactions

  • Antacids (aluminum or magnesium hydroxide)
  • Iron supplements
  • Probenecid

🍷 Alcohol Interaction

Alcohol does not directly interact with cefixime or lactobacillus, but drinking alcohol while you have an infection may worsen dehydration and slow recovery. It is best to avoid alcohol until you have completed the course and feel better.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cefixime, other cephalosporins, or any component of the formulation","History of severe allergic reaction to penicillin","Severe renal impairment without dose adjustment","Use in patients with a history of Clostridioides difficile-associated diarrhea"]

⚠️ Warnings & Precautions

["Use with caution in patients with penicillin allergy due to potential cross-reactivity.","May cause Clostridioides difficile-associated diarrhea; if severe diarrhea occurs, stop the medicine and consult a doctor.","Dose adjustment may be needed in patients with kidney disease.","May reduce the effectiveness of oral contraceptives; use backup contraception.","Do not use for viral infections as it is ineffective and may promote resistance.","Complete the full course as prescribed even if symptoms improve."]

🤱 Lactation Safety

Cefixime is excreted in small amounts in breast milk and is generally considered safe for breastfeeding mothers. Lactobacillus is also considered safe. However, monitor the infant for diarrhea or thrush. Consult your doctor before use.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, stomach pain, and diarrhea. In severe cases, it may lead to seizures, especially in patients with kidney disease. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases but is not routinely recommended.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better, because incomplete treatment can allow bacteria to become resistant. Take the tablet with a full glass of water, with or without food, but taking it with food may reduce stomach upset. Avoid taking antacids or iron supplements within two hours of this medicine, as they can reduce its absorption. If you are using other antibiotics or medications, inform your doctor. Do not share this medicine with others. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature, away from moisture and direct sunlight. Keep out of reach of children. If you experience severe diarrhea, rash, or difficulty breathing, seek medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function, which can affect the elimination of cefixime. Dose adjustment may be necessary. They should also be monitored for signs of allergic reactions and diarrhea.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Cefixime is generally considered safe during pregnancy, but the decision should be made with your healthcare provider.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with other medications used during surgery. Your doctor may advise you to stop it before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications or affect the procedure. Your dentist may recommend postponing non-urgent dental work until you complete the course.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water to help flush out the infection and stay hydrated.
🥗
Get adequate rest to support your immune system while fighting the infection.
😴
Eat a balanced diet rich in fruits and vegetables to boost your immunity.
💧
Practice good hygiene, such as washing hands frequently, to prevent the spread of infection.
🧘
Avoid sharing personal items like towels or utensils if you have an infection.
🌞
Complete the full course of antibiotics even if you feel better.

🏋️ Exercise Considerations

You can continue light to moderate exercise if you feel up to it, but avoid strenuous activities if you have fever, fatigue, or dizziness. Listen to your body and rest when needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to support gut health.
Stay well hydrated by drinking water, soups, and broths.
Eat light, easily digestible meals if you have stomach upset.
Avoid spicy or greasy foods that may irritate your stomach.
Include foods rich in vitamin C to support immune function.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or headache in some people. If you experience these side effects, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal daily activities while taking this medicine.

🛑 When to Stop This Medicine

Do not stop taking this medicine before completing the full prescribed course, even if you feel better. If you experience severe side effects such as severe diarrhea, rash, or difficulty breathing, stop the medicine and seek immediate medical attention. Always consult your doctor before stopping.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance and an imbalance in gut flora. If you need to take it for more than 2 weeks, your doctor should monitor your kidney and liver function. Always follow your doctor's advice regarding the duration of treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotic supplements

Can help maintain gut health during antibiotic treatment, but should be taken at least 2 hours apart from the antibiotic.

Evidence: Well-established
Increased fluid intake

Helps flush out bacteria from the urinary tract and supports recovery.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics like cefixime may reduce the effectiveness of live bacterial vaccines. Complete the antibiotic course before receiving live vaccines, or consult your doctor for timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Check local customs regulations regarding prescription medicines before you travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a urinary tract infection. She took it with food to avoid stomach upset and completed the 7-day course. Her symptoms improved within 3 days, and she felt back to normal by the end of the week. She also drank plenty of water as advised.
💡 Lesson: Taking the full course and staying hydrated helps ensure complete recovery and prevents recurrence.
👤 A 50-year-old man with bronchitis
He started this medicine for bronchitis and noticed improvement in his cough and breathing within 2 days. He experienced mild loose stools, which resolved after he started taking the tablet with meals. He completed the 10-day course and recovered fully.
💡 Lesson: Mild side effects like loose stools are common but manageable by taking the medicine with food. Completing the course is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: Cefixime is generally considered safe during pregnancy when prescribed by a doctor. Consult your doctor before taking any medicine during pregnancy.

Q: Can I drink alcohol while taking this medicine?

A: It is best to avoid alcohol until you complete the course and feel better, as alcohol may worsen dehydration and slow recovery.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other antibiotics?

🔄 Substitutes for alcef lb 200 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not work for viral infections.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full prescribed course to ensure all bacteria are killed and to prevent resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This is a prescription medicine. It should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Cefixime 200 mg + Lactobacillus 2.5 million spores tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cefixime 200 mg + Lactobacillus 2.5 million spores","key_feature":"Antibiotic with probiotic support"},{"medicine":"Cefixime 200 mg tablet","composition":"Cefixime 200 mg","key_feature":"Antibiotic only"},{"medicine":"Cefixime 200 mg + Ofloxacin 200 mg tablet","composition":"Cefixime 200 mg + Ofloxacin 200 mg","key_feature":"Dual antibiotic combination"}]

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