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brigat 200mg tablet

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Gatifloxacin (200mg)

🏭 Briskon Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Jul 4, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Jul 04, 2026

What is brigat 200mg tablet used for?

Abgate (Gatifloxacin) is used to treat GASTRO INTESTINAL. It contains Gatifloxacin (200mg), which Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication a. Always consult your doctor before use. Take as prescribed.

Generic Name: Gatifloxacin
Manufacturer: Briskon Laboratories
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 brigat 200mg tablet Uses & Benefits

Treatment of acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute sinusitis, uncomplicated urinary tract infections, and pyelonephritis.

Off-label uses: Bacterial prostatitis, Gonorrhea, Traveler's diarrhea

📋 Drug Information

Generic Name(s)	Gatifloxacin
Brand Name	Abgate
Manufacturer	Briskon Laboratories
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Quinolones/ Fluroquinolones
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; bioavailability approximately 96%.

DistributionWidely distributed into tissues and fluids; high concentrations in lung, sinus, and urinary tract.

Protein BindingApproximately 20% bound to plasma proteins.

MetabolismMinimal hepatic metabolism; primarily excreted unchanged.

Half-Life7-14 hours

ExcretionPrimarily excreted unchanged in urine (70-80%) and feces.

Bioavailability96%

Onset of ActionRapid; within 1-2 hours.

Peak Plasma Time1-2 hours

Duration of ActionApproximately 12-24 hours

How It Works

Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and transcription.

Mechanism Steps

1Gatifloxacin enters bacterial cell via porin channels.

2Binds to DNA gyrase (topoisomerase II) and topoisomerase IV.

3Inhibits supercoiling and relaxation of bacterial DNA.

💡 How to Take brigat 200mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of brigat 200mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Headache
Dizziness
Insomnia

🚨 Serious Side Effects

Tendon rupture
QT prolongation
Hypoglycemia
Seizures
Peripheral neuropathy

⚠️ Rare Side Effects

Anaphylaxis
Stevens-Johnson syndrome
Hepatotoxicity
Clostridium difficile colitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Insulin	Major	Enhanced hypoglycemic effect
NSAIDs	Moderate	Increased risk of CNS stimulation and seizures
Antacids (Mg/Al)	Moderate	Reduced absorption of gatifloxacin
Corticosteroids	Moderate	Increased risk of tendon rupture

🚨 Major Interactions

Class IA antiarrhythmics
Class III antiarrhythmics
Insulin
Oral hypoglycemics

⚡ Moderate Interactions

NSAIDs
Corticosteroids
Antacids containing magnesium or aluminum
Sucralfate
Iron supplements
Zinc supplements

ℹ️ Minor Interactions

Caffeine
Theophylline

🍽️ Food Interactions

Avoid dairy products, antacids, and iron supplements within 2-4 hours of dosing.

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of CNS effects and hypoglycemia.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to gatifloxacin or any fluoroquinolone; history of tendon disorders; epilepsy; QT prolongation; uncorrected hypokalemia; concurrent use with Class IA or III antiarrhythmics.

📊 Monitoring Parameters

Renal function, blood glucose, ECG (QT interval), signs of tendonitis or CNS effects.

🤱 Lactation Safety

Excreted in breast milk; avoid use or discontinue breastfeeding.

💊 Overdose Management

Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis may remove drug.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Jul 04, 2026

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🔄 Substitutes for brigat 200mg tablet

View All

Alternative brands with exact same active ingredient (Gatifloxacin (200mg)):

Medical Note: Always consult your doctor before switching medications.

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📌 Quick Facts

Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Route	Oral
Pregnancy	Category C
Breastfeeding	Excreted in breast milk; avoid use or discontinue breastfeeding.
Alcohol	Avoid alcohol; may increase risk of CNS effects and hypoglycemia.
Onset of Action	Rapid; within 1-2 hours.
Half-Life	7-14 hours
Prescription	✅ Required

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