Agicof Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe headache, chest pain, or shortness of breath
- Irregular or rapid heartbeat
- Confusion, hallucinations, or unusual behavior
- Seizures or loss of consciousness
- Swelling of face, lips, tongue, or throat
- Difficulty urinating or no urine output
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is breath dx syrup used for?
This medicine is a combination of phenylpropanolamine and chlorpheniramine maleate used for temporary relief of nasal congestion, sneezing, and runny nose due to colds or allergies. It works by shrinking nasal blood vessels and blocking histamine. It can cause drowsiness, so avoid driving. Do not use for more than 7 days without medical advice.
- Generic Name: Phenylpropanolamine + Chlorpheniramine Maleate
- Manufacturer: Hippo Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 breath dx syrup के बारे में (Hindi Summary)
उपयोग: यह दवा आम सर्दी, एलर्जी और नाक बंद होने के लक्षणों से राहत दिलाने के लिए इस्तेमाल की जाती है। इसमें फेनिलप्रोपेनॉलामाइन नाक की भीड़ को कम करता है और क्लोरफेनिरामाइन मेलिएट छींक, खुजली और बहती नाक को रोकता है। यह सिरप के रूप में मौखिक रूप से ली जाती है। इसका उपयोग केवल अल्पकालिक राहत के लिए किया जाना चाहिए, आमतौर पर 7 दिनों से अधिक नहीं। इसे लेने से नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। उच्च रक्तचाप, हृदय रोग, ग्लूकोमा या पेशाब में रुकावट वाले रोगियों को इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुँह सूखना, चक्कर आना, धुंधली दृष्टि और हल्का पेट खराब होना शामिल है। कुछ लोगों को बेचैनी, घबराहट या अनिद्रा हो सकती है। दुर्लभ मामलों में दिल की धड़कन तेज होना, रक्तचाप बढ़ना या पेशाब करने में कठिनाई हो सकती है। गंभीर दुष्प्रभाव जैसे गंभीर एलर्जी प्रतिक्रिया, दौरे या मतिभ्रम बहुत दुर्लभ हैं, लेकिन तुरंत चिकित्सा सहायता की आवश्यकता होती है।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। शराब और अन्य नींद लाने वाली दवाओं से बचें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, वाहन न चलाएं। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या प्रोस्टेट की समस्या है तो अपने डॉक्टर को बताएं। 7 दिनों से अधिक इसका उपयोग न करें। बच्चों की पहुंच से दूर रखें।
💊 breath dx syrup Uses & Benefits
[{"condition":"Common cold with nasal congestion","description":"Provides temporary relief of nasal stuffiness and sneezing associated with the common cold.","evidence":"Established for short-term symptomatic relief"},{"condition":"Allergic rhinitis","description":"Helps reduce runny nose, sneezing, and itchy, watery eyes due to seasonal or perennial allergies.","evidence":"Established for short-term symptomatic relief"},{"condition":"Sinusitis with congestion","description":"May alleviate nasal congestion and pressure in acute sinusitis as an adjunct to other treatments.","evidence":"Limited, used for symptomatic relief"},{"condition":"Vasomotor rhinitis","description":"Can reduce nasal congestion and rhinorrhea in non-allergic rhinitis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Motion sickness","description":"Chlorpheniramine maleate may help prevent motion sickness due to its antihistamine effects.","evidence":"Limited"},{"condition":"Insomnia due to allergic symptoms","description":"The sedating effect of chlorpheniramine may help sleep in patients with allergic symptoms, but this is not a primary indication.","evidence":"Limited"}]
Primary treatment for: Common cold and allergic rhinitis
Also treats: Sinusitis, Vasomotor rhinitis
📋 Drug Information
| Generic Name(s) | Phenylpropanolamine + Chlorpheniramine Maleate |
| Brand Name | Axn Syrup |
| Manufacturer | Hippo Labs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Sympathomimetic + Antihistamine |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep the bottle tightly closed. Do not freeze. |
| Shelf Life | Not established from the available information. Refer to the product packaging for the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Phenylpropanolamine is a sympathomimetic amine that directly and indirectly stimulates alpha-adrenergic receptors, causing vasoconstriction of nasal mucosal blood vessels and reducing congestion. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing sneezing, itching, and rhinorrhea. Additionally, chlorpheniramine has anticholinergic properties that contribute to drying of secretions.
Mechanism Steps
💡 How to Take breath dx syrup
Strength: Not established from the available information.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 to 10 mL orally every 4 to 6 hours as needed for symptoms, not to exceed 6 doses in 24 hours. However, the exact dose must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications being taken. Do not self-medicate beyond the recommended duration. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine and the cardiovascular effects of phenylpropanolamine. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Do not exceed the dose recommended by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of breath dx syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Other sympathomimetics | Major | |
| Tricyclic antidepressants | Major | |
| Alcohol | Moderate | |
| CNS depressants | Moderate | |
| Anticholinergics | Moderate | |
| Beta-blockers | Moderate | |
| Caffeine | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Other sympathomimetics (e.g., pseudoephedrine, phenylephrine)
- Tricyclic antidepressants
⚡ Moderate Interactions
- Alcohol and CNS depressants (e.g., benzodiazepines, opioids)
- Anticholinergic drugs (e.g., atropine, oxybutynin)
- Beta-blockers
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impairment of judgment and motor skills. It may also enhance the central nervous system depressant effects of chlorpheniramine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to phenylpropanolamine, chlorpheniramine, or any component of the formulation","Uncontrolled hypertension","Severe coronary artery disease","Hyperthyroidism","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Use within 14 days of MAO inhibitor therapy","Newborns and premature infants"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until effects are known.","Use with caution in patients with cardiovascular disease, hypertension, diabetes, or thyroid disorders.","Do not exceed recommended dose or duration of use.","Avoid alcohol and other CNS depressants.","Consult a doctor before use in pregnancy, breastfeeding, or in children under 12 years.","May cause anticholinergic effects such as dry mouth, constipation, and blurred vision.","Do not use for persistent or chronic symptoms without medical evaluation."]
🤱 Lactation Safety
Not established from the available information. Both phenylpropanolamine and chlorpheniramine may pass into breast milk. Consult a doctor before use during breastfeeding.
💊 Overdose Management
Overdose may cause severe hypertension, tachycardia, arrhythmias, hallucinations, seizures, and respiratory depression. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide symptomatic care. Seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose or duration of use. Avoid alcohol and other central nervous system depressants because they can increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or prostate enlargement. Do not use this medicine for longer than 7 days without medical advice. Keep out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the sedative, anticholinergic, and cardiovascular effects of this medicine. Use with caution, and lower doses may be appropriate. Monitor blood pressure and mental status closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy is not well established.
🏥 Post-Surgery Considerations
This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery as advised by your doctor.
🦷 Dental Procedures
This medicine can cause dry mouth, which may increase the risk of dental caries and oral discomfort. Inform your dentist that you are taking this medicine, especially if you are undergoing dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may impair your ability to exercise safely. Avoid strenuous exercise or activities requiring balance until you know how the medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and impair concentration, which may affect your ability to work, drive, or operate machinery. It is best to avoid these activities until you know how the medicine affects you. Consider taking it at bedtime if your symptoms allow.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe headache, chest pain, palpitations, or difficulty urinating.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of decongestants like phenylpropanolamine can lead to rebound congestion, and antihistamines like chlorpheniramine may cause tolerance to sedative effects. Regular monitoring of blood pressure and heart rate is advised if used for extended periods under medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Using saline sprays or rinses can help relieve nasal congestion without medication.
Evidence: Well-establishedInhaling steam from a hot shower or bowl of hot water can temporarily ease nasal stuffiness.
Evidence: LimitedPrescription nasal antihistamines may be an alternative for allergic rhinitis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. This medicine does not interact with vaccines, but if you are acutely ill with a fever, consult your doctor about timing of vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, adjust dosing intervals as advised by your doctor. Check local customs regulations regarding carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving nasal congestion within 30 to 60 minutes after taking a dose.
A: The effects typically last about 4 to 6 hours, so it may need to be taken every 4 to 6 hours as directed.
A: You should avoid this medicine if you have uncontrolled high blood pressure unless your doctor specifically approves it, as it can raise blood pressure.
A: Pediatric dosing is not established from available information. Consult a pediatrician before giving this medicine to a child.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for breath dx syrup
View AllAlternative brands with exact same active ingredient:
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nircough dmr syrupNirlife Healthcare ₹5.00 88.1% CHEAPER
-
colkoff capsuleGlenmark Pharmaceuticals Ltd ₹12.50 70.4% CHEAPER
-
kop q d syrupKopran Ltd ₹14.48 65.7% CHEAPER
-
coldgesic dp syrupDew Drops Lab ₹17.53 58.4% CHEAPER
-
dexcoff syrupCipla Ltd ₹20.17 52.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take this medicine for weeks.
Fact: It should only be used for short-term relief, typically not more than 7 days, unless directed by a doctor. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with certain conditions like uncontrolled hypertension, heart disease, or glaucoma.