biokinase 1500000iu injection - Streptokinase (1500000IU) medicine

biokinase 1500000iu injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Biological E Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 3, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 03, 2026

What is biokinase 1500000iu injection used for?

Allkinase 1500000IU Injection (Streptokinase) is used to treat CARDIAC. It contains Streptokinase (1500000IU), which Forms a complex with plasminogen, converting it to plasmin, which degrades fibri. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Streptokinase
  • Manufacturer: Biological E Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š biokinase 1500000iu injection Uses & Benefits

Acute myocardial infarction, pulmonary embolism, deep vein thrombosis, arterial thromboembolism.

Off-label uses: Peripheral arterial occlusion, thrombosed arteriovenous cannulae.

๐Ÿ“‹ Drug Information

Generic Name(s)Streptokinase
Brand NameAllkinase 1500000IU Injection
ManufacturerBiological E Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassFirst Generation Thrombolytics
Route of AdministrationIntravenous (IV) infusion or bolus.
StorageStore at 2-8ยฐC; protect from light; reconstituted solution stable for 24 hours at room temperature.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in immediate systemic availability.
DistributionDistributes throughout the extracellular fluid; not significantly bound to tissues.
Protein BindingMinimal protein binding.
MetabolismMetabolized primarily in the liver via proteolytic degradation.
Half-LifeApproximately 23 minutes (initial); prolonged after formation of antibodies.
ExcretionExcreted in urine as inactive metabolites.
Bioavailability100% (intravenous).
Onset of ActionImmediate (within minutes).
Peak Plasma TimeNot applicable (continuous infusion or bolus).
Duration of ActionUp to 12-24 hours due to prolonged fibrinolytic effect.

How It Works

Forms a complex with plasminogen, converting it to plasmin, which degrades fibrin clots.

Mechanism Steps

1Streptokinase binds to circulating plasminogen to form a streptokinase-plasminogen activator complex.
2This complex converts inactive plasminogen to active plasmin.
3Plasmin degrades fibrin clots, fibrinogen, and other coagulation factors (V, VIII).

๐Ÿ’ก How to Take biokinase 1500000iu injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of biokinase 1500000iu injection

โœ… Common Side Effects

  • Bleeding (minor)
  • Nausea
  • Vomiting
  • Hypotension
  • Fever

๐Ÿšจ Serious Side Effects

  • Intracranial hemorrhage
  • Major bleeding
  • Anaphylaxis
  • Reperfusion arrhythmias

โš ๏ธ Rare Side Effects

  • Cholesterol embolization
  • Allergic reactions (rash, urticaria)
  • Hemolytic uremic syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Heparin Major Increased bleeding risk
Aspirin Major Increased bleeding risk
Clopidogrel Major Increased bleeding risk
NSAIDs Moderate Increased bleeding risk
Corticosteroids Moderate Increased bleeding risk
Antifibrinolytics Moderate Reduced efficacy of streptokinase

๐Ÿšจ Major Interactions

  • Warfarin
  • Heparin
  • Aspirin
  • Clopidogrel
  • Other anticoagulants/antiplatelets

โšก Moderate Interactions

  • NSAIDs
  • Corticosteroids
  • Antifibrinolytic agents

โ„น๏ธ Minor Interactions

  • Herbal supplements with anticoagulant effects (e.g., ginkgo, garlic)

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

May increase bleeding risk; avoid excessive alcohol consumption.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Active internal bleeding, recent surgery/trauma, history of stroke, severe hypertension, known hypersensitivity to streptokinase.

๐Ÿ“Š Monitoring Parameters

Bleeding time, fibrinogen levels, PT/PTT, signs of bleeding, vital signs.

๐Ÿคฑ Lactation Safety

Not recommended; unknown if excreted in breast milk.

๐Ÿ’Š Overdose Management

Discontinue infusion; administer fresh frozen plasma, cryoprecipitate, or antifibrinolytics (e.g., tranexamic acid).

โฐ Missed Dose

Not applicable (given as a single dose or continuous infusion).

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 03, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for biokinase 1500000iu injection

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Alternative brands with exact same active ingredient (Streptokinase (1500000IU)):

Medical Note: Always consult your doctor before switching medications.

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