bethadoxin 12 injection
What is bethadoxin 12 injection used for?
Axcob Forte Injection (Methylcobalamin + Thiamine) is used to treat VITAMINS MINERALS NUTRIENTS. It contains Methylcobalamin (500mcg) + Thiamine(Vitamin B1) (50mg), which Methylcobalamin acts as a cofactor for methionine synthase and methylmalonyl-CoA. Always consult your doctor before use. Take as prescribed.
- Generic Name: Methylcobalamin + Thiamine
- Manufacturer: Biological E Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bethadoxin 12 injection Uses & Benefits
Peripheral neuropathy, diabetic neuropathy, vitamin B12 deficiency, thiamine deficiency, neuralgia
Off-label uses: Chronic fatigue syndrome, fibromyalgia
๐ Drug Information
| Generic Name(s) | Methylcobalamin + Thiamine |
| Brand Name | Axcob Forte Injection |
| Manufacturer | Biological E Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | VITAMINS MINERALS NUTRIENTS |
| Action Class | Vitamins |
| Route of Administration | Intramuscular injection |
| Storage | Store at 20-25ยฐC, protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Methylcobalamin acts as a cofactor for methionine synthase and methylmalonyl-CoA mutase; Thiamine acts as a cofactor for several enzymes involved in carbohydrate metabolism
Mechanism Steps
๐ก How to Take bethadoxin 12 injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bethadoxin 12 injection
โ Common Side Effects
- Injection site pain
- Redness
- Swelling
๐จ Serious Side Effects
- Anaphylaxis
- Peripheral vascular thrombosis
โ ๏ธ Rare Side Effects
- Hypersensitivity reactions
- Urticaria
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Chloramphenicol | Major | May reduce efficacy of methylcobalamin |
| 5-Fluorouracil | Major | May decrease thiamine levels |
| Oral contraceptives | Moderate | May decrease thiamine levels |
| Loop diuretics | Moderate | May increase thiamine excretion |
| Alcohol | Minor | May reduce thiamine absorption |
| Caffeine | Minor | May increase thiamine excretion |
๐จ Major Interactions
- Chloramphenicol
- 5-Fluorouracil
โก Moderate Interactions
- Oral contraceptives
- Loop diuretics
โน๏ธ Minor Interactions
- Alcohol
- Caffeine
๐ฝ๏ธ Food Interactions
No significant food interactions
๐ท Alcohol Interaction
Alcohol may reduce thiamine absorption and increase excretion
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to any component
๐ Monitoring Parameters
Neurological function, vitamin B12 and thiamine levels
๐คฑ Lactation Safety
Safe; excreted in breast milk in small amounts
๐ Overdose Management
No specific antidote; supportive care
โฐ Missed Dose
Administer as soon as remembered; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.