biojoint 50mg tablet - Diacerein (50mg) medicine

Biojoint 50mg Tablet - Uses, Price, Side Effects

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๐Ÿญ Elfin Pharma Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is biojoint 50mg tablet used for?

Biojoint 50mg Tablet contains Diacerein, a disease-modifying agent for osteoarthritis. It inhibits interleukin-1, reducing inflammation and slowing cartilage breakdown. It is used to relieve pain and improve joint function in osteoarthritis patients. Take with food to avoid stomach upset.

  • Generic Name: Diacerein
  • Manufacturer: Elfin Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š biojoint 50mg tablet Uses & Benefits

Symptomatic treatment of osteoarthritis, particularly of the hip and knee.

Off-label uses: Rheumatoid arthritis (limited evidence), Ankylosing spondylitis

๐Ÿ“‹ Drug Information

Generic Name(s)Diacerein
Brand NameArtrodar 50mg Capsule
ManufacturerElfin Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassProteoglycan synthesis Stimulator
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionAbsorbed slowly after oral administration; peak plasma concentrations achieved in about 2-4 hours.
DistributionDistributes widely in tissues; crosses the blood-brain barrier to a limited extent.
Protein BindingApproximately 90% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via deacetylation to rhein, the active metabolite; also undergoes glucuronidation.
Half-LifeApproximately 7-8 hours for diacerein; rhein half-life is about 4-5 hours.
ExcretionExcreted primarily in urine (about 60%) as metabolites and unchanged drug; remainder in feces.
BioavailabilityAbout 35-56% due to first-pass metabolism.
Onset of ActionMay take 2-4 weeks for symptomatic relief.
Peak Plasma Time2-4 hours after oral administration.
Duration of ActionApproximately 24 hours; sustained effect with regular dosing.

How It Works

Inhibits interleukin-1 beta (IL-1ฮฒ) production and activity, thereby reducing cartilage degradation and inflammation.

Mechanism Steps

1Inhibition of IL-1ฮฒ production by chondrocytes and synovial cells
2Reduction of IL-1ฮฒ-induced matrix metalloproteinase (MMP) expression
3Decreased degradation of proteoglycans and collagen in cartilage

๐Ÿ’ก How to Take biojoint 50mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of biojoint 50mg tablet

โœ… Common Side Effects

  • Diarrhea
  • Soft stools
  • Abdominal pain
  • Nausea
  • Headache

๐Ÿšจ Serious Side Effects

  • Severe diarrhea leading to dehydration
  • Hepatotoxicity
  • Allergic reactions

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Angioedema

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Diuretics Moderate Reduced diuretic efficacy
Lithium Moderate Increased lithium toxicity

๐Ÿšจ Major Interactions

  • Warfarin
  • Anticoagulants

โšก Moderate Interactions

  • Diuretics
  • NSAIDs
  • Methotrexate

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 receptor antagonists

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption; take with or without food consistently.

๐Ÿท Alcohol Interaction

Avoid alcohol as it may increase risk of hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to diacerein or any excipients; severe hepatic impairment; inflammatory bowel disease; pregnancy and lactation.

๐Ÿ“Š Monitoring Parameters

Liver function tests, renal function, gastrointestinal symptoms.

๐Ÿคฑ Lactation Safety

Not recommended; excretion in breast milk unknown.

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; symptomatic and supportive treatment.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for biojoint 50mg tablet

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Alternative brands with exact same active ingredient (Diacerein (50mg)):

Medical Note: Always consult your doctor before switching medications.

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