Betaloc H 50mg/12.5mg Tablet: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heartbeat (below 50 beats per minute)
- Difficulty breathing or wheezing
- Chest pain or worsening angina
- Severe abdominal pain or vomiting
- Signs of electrolyte imbalance: muscle cramps, weakness, irregular heartbeat
- Yellowing of skin or eyes
- Decreased urine output
- Sudden swelling of face, lips, or throat
If experiencing severe symptoms, call emergency services immediately.
What is betaloc h 50mg/12.5mg tablet used for?
This medicine is a combination of metoprolol succinate (a beta-blocker) and hydrochlorothiazide (a diuretic) used to treat high blood pressure. It works by slowing the heart rate and removing excess fluid from the body. It is taken once daily, usually in the morning, and must be prescribed by a doctor.
- Generic Name: Metoprolol Succinate + Hydrochlorothiazide
- Manufacturer: AstraZeneca
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 betaloc h 50mg/12.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें मेटोप्रोलोल सक्सिनेट और हाइड्रोक्लोरोथियाजाइड दो दवाएं शामिल हैं। मेटोप्रोलोल दिल की धड़कन को धीमा करता है और रक्तचाप को कम करता है, जबकि हाइड्रोक्लोरोथियाजाइड शरीर से अतिरिक्त नमक और पानी को बाहर निकालता है। यह दवा अकेले दवा से रक्तचाप नियंत्रित न होने पर दी जाती है। इसे रोजाना सुबह एक बार लेना चाहिए। इसे डॉक्टर के परामर्श के बिना बंद न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, धीमी हृदय गति, कम रक्तचाप, मतली और बार-बार पेशाब आना शामिल हैं। गंभीर दुष्प्रभावों में गंभीर ब्रैडीकार्डिया, हृदय रुकावट, दिल की विफलता का बिगड़ना, ब्रोंकोस्पाज्म, गंभीर इलेक्ट्रोलाइट असंतुलन, तीव्र गाउट, अग्नाशयशोथ और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि दुष्प्रभाव लगातार बने रहें तो डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अचानक बंद न करें क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। नियमित रूप से रक्तचाप और नाड़ी की जांच करें। पर्याप्त पानी पिएं लेकिन अगर डॉक्टर ने तरल पदार्थ प्रतिबंधित किया है तो सावधानी बरतें। शराब से बचें क्योंकि इससे चक्कर और कम रक्तचाप बढ़ सकता है। पोटेशियम सप्लीमेंट या नमक के विकल्प डॉक्टर की सलाह के बिना न लें। यदि आपको मधुमेह, अस्थमा, गुर्दे या यकृत रोग है तो डॉक्टर को बताएं।
💊 betaloc h 50mg/12.5mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"Used to lower blood pressure in patients whose blood pressure is not controlled by a single agent.
- The combination reduces cardiovascular risk.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Metoprolol component helps reduce angina attacks by decreasing heart rate and myocardial oxygen demand.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"Metoprolol succinate is indicated for stable heart failure, but the combination with hydrochlorothiazide is not typically used for this indication alone.","evidence":"Well-established for metoprolol component"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Beta-blockers like metoprolol are sometimes used off-label to prevent migraines, but the combination with hydrochlorothiazide is not standard for this purpose.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Beta-blockers may be used off-label for situational anxiety, but this combination is not recommended due to the diuretic component.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Heart failure with reduced ejection fraction (metoprolol component)
📋 Drug Information
| Generic Name(s) | Metoprolol Succinate + Hydrochlorothiazide |
| Brand Name | Betaloc H 50mg/12.5mg Tablet |
| Manufacturer | AstraZeneca |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Antihypertensive (Beta-blocker + Thiazide diuretic) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Metoprolol succinate selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output. It also suppresses renin release from the kidneys. Hydrochlorothiazide inhibits the sodium-chloride symporter in the distal convoluted tubule of the nephron, increasing excretion of sodium, chloride, and water. This reduces plasma volume and cardiac preload, leading to lowered blood pressure. The two agents work synergistically to reduce blood pressure through complementary mechanisms.
Mechanism Steps
💡 How to Take betaloc h 50mg/12.5mg tablet
Strength: Tablet containing metoprolol succinate 50 mg and hydrochlorothiazide 12.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet of metoprolol succinate 50 mg and hydrochlorothiazide 12.5 mg taken orally once daily, preferably in the morning. The dose may be adjusted by your doctor based on blood pressure response and tolerability. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and hypotension. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, hydrochlorothiazide may accumulate and cause electrolyte disturbances. Metoprolol dose may need adjustment. Consult your doctor for dose adjustments based on creatinine clearance. |
| Hepatic Impairment | In patients with hepatic impairment, metoprolol metabolism may be reduced, leading to increased effects. Start with a lower dose and monitor closely. Consult your doctor for dose adjustments. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of metoprolol succinate 50 mg and hydrochlorothiazide 12.5 mg. Higher doses may be prescribed by your doctor based on clinical response, but do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of betaloc h 50mg/12.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Digoxin | Major | |
| Clonidine | Major | |
| MAOIs | Major | |
| Lithium | Major | |
| NSAIDs | Major | |
| Fluoxetine | Moderate | |
| Rifampin | Moderate | |
| Corticosteroids | Moderate | |
| Antidiabetic drugs | Moderate |
🚨 Major Interactions
- Verapamil or diltiazem
- Digoxin
- Clonidine
- Monoamine oxidase inhibitors (MAOIs)
- Lithium
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- CYP2D6 inducers (e.g., rifampin)
- Corticosteroids
- Antidiabetic drugs
- Other antihypertensives
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering and central nervous system effects of this medicine, leading to dizziness, fainting, and increased risk of falls. It is advisable to avoid alcohol or limit intake significantly while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second- or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Sick sinus syndrome without pacemaker","Severe peripheral arterial disease","Anuria","Sulfonamide allergy","Severe renal impairment (eGFR
⚠️ Warnings & Precautions
["Do not stop abruptly; taper gradually to avoid rebound angina or hypertension.","Use with caution in patients with asthma or COPD; may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetics.","Can cause electrolyte imbalances; monitor potassium and sodium.","May worsen psoriasis and Raynaud's phenomenon.","Use caution in patients with myasthenia gravis.","Avoid in patients with pheochromocytoma unless alpha-blockade is established.","May cause photosensitivity; use sun protection.","Can increase blood glucose and uric acid levels.","Use with caution in elderly patients; increased risk of falls."]
🤱 Lactation Safety
Metoprolol is excreted in breast milk in small amounts; hydrochlorothiazide is also excreted in breast milk and may suppress lactation. Consult your doctor before breastfeeding; monitoring of infant for signs of beta-blockade is advised.
💊 Overdose Management
Overdose may cause severe bradycardia, hypotension, heart failure, bronchospasm, and electrolyte disturbances. Treatment is supportive and symptomatic. For metoprolol overdose, consider glucagon, atropine, or pacemaker. For hydrochlorothiazide overdose, monitor electrolytes and hydrate. Seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not stop suddenly because abrupt withdrawal of metoprolol can worsen angina or cause a heart attack. Monitor your blood pressure and pulse regularly. Stay hydrated but avoid excessive fluid intake if your doctor has restricted fluids. Avoid alcohol as it can worsen dizziness and low blood pressure. Do not take potassium supplements or salt substitutes without consulting your doctor. Inform your doctor if you have diabetes, asthma, kidney disease, or liver disease. Use caution while driving or operating machinery until you know how this medicine affects you.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to dizziness, hypotension, and electrolyte imbalances. Start with a lower dose and monitor closely. Regular assessment of renal function and electrolytes is important. Falls risk may be increased.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before conception. This medicine is generally not recommended during pregnancy. Your doctor may switch you to a safer alternative. Use effective contraception while taking this medicine unless otherwise advised.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Your doctor may advise temporary discontinuation or dose adjustment.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or increase bleeding risk. Your dentist may need to take precautions, especially if you are also taking blood thinners.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is generally safe and beneficial, but avoid strenuous activities initially as this medicine may cause dizziness or fatigue. Stay hydrated, especially if exercising in hot weather. Monitor your heart rate and stop if you feel dizzy or short of breath.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause increased urination, so plan bathroom breaks. Most people can continue their normal activities with dose adjustment.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor may decide to stop or change the medicine if you experience severe side effects, your blood pressure is well controlled for a long time, or you develop contraindications. Abrupt withdrawal can cause rebound hypertension, angina, or heart attack.
📅 Long-Term Use Effects
Long-term use may require regular monitoring of blood pressure, heart rate, electrolytes, kidney function, and blood sugar. Prolonged use of hydrochlorothiazide may increase the risk of electrolyte imbalances, gout, and skin cancer. Metoprolol may cause fatigue and sexual dysfunction. Regular follow-up with your doctor is essential to adjust the dose and monitor for complications.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, or other beta-blockers may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine. Annual flu vaccination is recommended for patients with cardiovascular disease.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. If traveling across time zones, consult your doctor about adjusting the timing. Store at room temperature and protect from moisture. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but it may take 1-2 weeks to see the full effect. Your doctor will monitor your blood pressure regularly.
A: No, do not stop without consulting your doctor. High blood pressure often requires long-term treatment, and stopping suddenly can cause rebound hypertension or angina.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Consult your doctor. This medicine is generally not recommended during pregnancy, especially in the second and third trimesters, as it may harm the fetus.
A: It is advisable to avoid alcohol as it can worsen dizziness and low blood pressure.
🤔 Common Patient Concerns
🔄 Substitutes for betaloc h 50mg/12.5mg tablet
View AllAlternative brands with exact same active ingredient:
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beboxia h tabletWings Biotech Ltd ₹50.21 63% COSTLIER
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Topme-H 50/12.5 Tablet SRJohnlee Pharmaceuticals Pvt Ltd ₹60.94 97.9% COSTLIER
-
metonce h 50mg/12.5 mg tablet xlMSN Laboratories ₹65.00 111% COSTLIER
-
metomac h 50mg/12.5mg tablet erMacleods Pharmaceuticals Pvt Ltd ₹65.71 113.3% COSTLIER
-
metolet h 50mg/12.5mg tablet xlIkon Remedies Pvt Ltd ₹69.84 126.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often requires long-term treatment. Stopping suddenly can cause rebound hypertension or angina. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: When used as prescribed and monitored, this medicine is safe for most people. It may affect kidney function in some patients, so regular monitoring is important. - Myth: You can take this medicine without a prescription.
Fact: This is a prescription-only medicine. It should only be taken under a doctor's supervision.
🔄 Alternative Options
Generic Alternatives
- Metoprolol succinate + hydrochlorothiazide generic tablets
Brand Alternatives
- Betaloc H 50mg/12.5mg tablet