Embeta HT 50 Tablet ER: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Very slow or irregular heartbeat
- Fainting or severe dizziness
- Difficulty breathing or wheezing
- Swelling of the face, lips, tongue, or throat
- Chest pain or tightness
- Severe abdominal pain with nausea and vomiting
- Decreased urine output or extreme thirst
- Yellowing of the skin or eyes
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is metomac h 50mg/12.5mg tablet er used for?
This medicine is a combination of metoprolol succinate and hydrochlorothiazide used to treat high blood pressure. It works by slowing the heart rate and removing excess fluid from the body. It is a prescription medicine and should be taken exactly as directed by your doctor.
- Generic Name: Metoprolol Succinate (50mg) + Hydrochlorothiazide (12.5mg)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 metomac h 50mg/12.5mg tablet er के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह मेटोप्रोलोल सक्सिनेट और हाइड्रोक्लोरोथियाजाइड का संयोजन है। यह दिल की धड़कन को धीमा करती है और शरीर से अतिरिक्त पानी और नमक को बाहर निकालती है, जिससे रक्तचाप कम होता है। यह एंजाइना (सीने में दर्द) और दिल की विफलता में भी मदद कर सकती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में थकान, चक्कर आना, सिरदर्द, और धड़कन का धीमा होना शामिल हैं। कुछ लोगों को ठंडे हाथ-पैर, पेट की गड़बड़ी, या बार-बार पेशाब आना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन तुरंत डॉक्टर से संपर्क करना चाहिए। इनमें बहुत धीमी धड़कन, बेहोशी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और इलेक्ट्रोलाइट असंतुलन के लक्षण जैसे मांसपेशियों में ऐंठन, कमजोरी, या भ्रम शामिल हैं।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें, क्योंकि इससे एंजाइना या दिल का दौरा पड़ सकता है। इसे रोज एक ही समय पर लें। गोली को चबाएं या तोड़ें नहीं। अगर आपको मधुमेह है, तो ब्लड शुगर की निगरानी करें क्योंकि यह दवा लो ब्लड शुगर के लक्षणों को छिपा सकती है। शराब से बचें। पर्याप्त पानी पिएं। नियमित रूप से ब्लड प्रेशर, हृदय गति, गुर्दे की कार्यप्रणाली और इलेक्ट्रोलाइट स्तर की जांच कराएं।
💊 metomac h 50mg/12.5mg tablet er Uses & Benefits
- [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure when a combination of a beta-blocker and a diuretic is appropriate.
- It reduces both heart rate and fluid volume to achieve blood pressure control.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"Metoprolol reduces the heart's workload and oxygen demand, which can help prevent chest pain episodes.
- The diuretic component may be added if blood pressure control is also needed.","evidence":"Well-established"},{"condition":"Heart failure with reduced ejection fraction","description":"Metoprolol succinate is proven to improve survival in certain patients with heart failure.
- The addition of hydrochlorothiazide may be used to manage fluid retention and blood pressure.","evidence":"Well-established"},{"condition":"Post-myocardial infarction","description":"Beta-blockers like metoprolol are often prescribed after a heart attack to reduce the risk of future cardiovascular events.
- A diuretic may be added for blood pressure management.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Metoprolol is sometimes used off-label to prevent migraines, though it is not approved for this purpose. The combination with hydrochlorothiazide is not typically used for this indication.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Beta-blockers like metoprolol may be used off-label to reduce symptoms of performance anxiety, such as tremors and rapid heartbeat. This combination product is not intended for this use.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Heart failure, Post-myocardial infarction
📋 Drug Information
| Generic Name(s) | Metoprolol Succinate (50mg) + Hydrochlorothiazide (12.5mg) |
| Brand Name | metomac h 50mg/12.5mg tablet er |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Metoprolol succinate is a cardioselective beta-1 adrenergic receptor blocker. It reduces heart rate, contractility, and cardiac output, thereby lowering blood pressure and myocardial oxygen demand. Hydrochlorothiazide is a thiazide diuretic that inhibits the sodium-chloride symporter in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water. This reduces plasma volume and cardiac preload, contributing to blood pressure reduction. Over time, thiazides also reduce peripheral vascular resistance.
Mechanism Steps
💡 How to Take metomac h 50mg/12.5mg tablet er
Strength: Extended-release tablet containing 50 mg metoprolol succinate and 12.5 mg hydrochlorothiazide.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and electrolyte imbalances. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Hydrochlorothiazide may accumulate and cause electrolyte disturbances. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Metoprolol is metabolized in the liver; dose reduction may be required. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet of 50 mg metoprolol succinate and 12.5 mg hydrochlorothiazide. Higher doses may be prescribed by your doctor based on your condition. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of metomac h 50mg/12.5mg tablet er
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| Fluoxetine | Major | |
| Lithium | Major | |
| Ibuprofen | Moderate | |
| Digoxin | Moderate | |
| Corticosteroids | Moderate | |
| Antidiabetic drugs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Verapamil or diltiazem
- Clonidine
- Monoamine oxidase inhibitors (MAOIs)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- Lithium
⚡ Moderate Interactions
- NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Antidiabetic drugs
- Digoxin
- Other antihypertensives
🍷 Alcohol Interaction
Alcohol can enhance the blood pressure-lowering and dizziness-causing effects of this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Second- or third-degree heart block","Cardiogenic shock","Decompensated heart failure","Severe asthma or COPD","Anuria","Hypersensitivity to metoprolol, hydrochlorothiazide, or sulfonamide-derived drugs","Severe hepatic impairment","Severe renal impairment"]
⚠️ Warnings & Precautions
["Do not stop this medicine abruptly; taper gradually to avoid rebound angina or hypertension.","May mask symptoms of hypoglycemia in diabetic patients.","May worsen symptoms of peripheral vascular disease.","Can cause electrolyte imbalances; monitor regularly.","May increase blood sugar and uric acid levels.","Use with caution in patients with a history of severe allergic reactions.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
Metoprolol is excreted in breast milk in small amounts. Hydrochlorothiazide is also excreted in breast milk and may suppress lactation. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose of this medicine can cause severe bradycardia, hypotension, heart failure, bronchospasm, and electrolyte disturbances. Seek immediate medical attention. Treatment is supportive and may include activated charcoal, intravenous fluids, atropine for bradycardia, and electrolyte replacement. Hemodialysis may be considered for hydrochlorothiazide overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not stop taking this medicine suddenly, because abrupt withdrawal of metoprolol can worsen angina or lead to a heart attack. If you need to stop, your doctor will reduce the dose gradually over one to two weeks. Take this medicine with or without food, but try to take it at the same time each day. Swallow the tablet whole; do not crush, chew, or break it, because it is an extended-release formulation. If you have diabetes, be aware that this medicine can hide the signs of low blood sugar, such as fast heartbeat and shakiness. Check your blood sugar regularly and inform your doctor if you notice any changes. Avoid drinking alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Stay well hydrated, especially in hot weather or during exercise, to prevent dehydration from the diuretic component. Do not use potassium supplements or salt substitutes containing potassium without your doctor's approval. Keep all follow-up appointments and get your blood pressure, heart rate, kidney function, and electrolyte levels checked regularly. Inform any healthcare provider you see that you are taking this medicine, especially before surgery or dental procedures.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially dizziness, electrolyte imbalances, and slow heart rate. Start with a lower dose and monitor closely. Regular monitoring of renal function and electrolytes is important.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Metoprolol and hydrochlorothiazide may not be suitable during pregnancy. Your doctor may switch you to a safer alternative.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect heart rate and blood pressure. Your doctor may advise you to stop or adjust the dose before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with local anesthetics containing epinephrine and affect blood pressure and heart rate. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness and slow heart rate, especially when starting treatment or after dose changes. Avoid strenuous exercise until you know how the medicine affects you. Stay hydrated during exercise, as the diuretic component can cause fluid loss. If you experience chest pain, severe shortness of breath, or dizziness during exercise, stop and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tiredness, and slow heart rate, which can affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how the medicine affects you. Take the medicine in the morning to minimize nighttime urination. Inform your employer if your job involves operating machinery or driving.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your doctor decides to discontinue treatment, the dose will be gradually reduced over one to two weeks to prevent rebound hypertension, angina, or heart attack. If you need to stop for any reason, contact your doctor first.
📅 Long-Term Use Effects
Long-term use of this medicine requires regular monitoring of blood pressure, heart rate, kidney function, and electrolyte levels. It may increase blood sugar and uric acid levels, so diabetic and gout patients need close monitoring. Prolonged use of hydrochlorothiazide can lead to electrolyte imbalances, particularly low potassium and sodium. Metoprolol may cause fatigue, sexual dysfunction, and depression in some patients. Regular follow-up with your doctor is essential to adjust the dose and manage any side effects.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, or other beta-blockers may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip plus extra in case of delays. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 1-2 weeks. It may take several weeks to achieve optimal blood pressure control.
A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause serious complications.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Some medicines can interact with this medicine. Always inform your doctor about all medicines, supplements, and herbal products you are taking.
🤔 Common Patient Concerns
🔄 Substitutes for metomac h 50mg/12.5mg tablet er
View AllAlternative brands with exact same active ingredient:
-
betaloc h 50mg/12.5mg tabletAstraZeneca ₹30.80 53.1% CHEAPER
-
beboxia h tabletWings Biotech Ltd ₹50.21 23.6% CHEAPER
-
Topme-H 50/12.5 Tablet SRJohnlee Pharmaceuticals Pvt Ltd ₹60.94 7.3% CHEAPER
-
metonce h 50mg/12.5 mg tablet xlMSN Laboratories ₹65.00 1.1% CHEAPER
-
metolet h 50mg/12.5mg tablet xlIkon Remedies Pvt Ltd ₹69.84 6.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause serious complications. - Myth: This medicine causes kidney damage.
Fact: When used as prescribed and monitored, this medicine is safe. Regular monitoring helps prevent kidney problems. - Myth: You can take this medicine without a prescription.
Fact: This is a prescription medicine. It should only be taken under a doctor's supervision.
🔄 Alternative Options
Generic Alternatives
- Metoprolol succinate + hydrochlorothiazide (generic)
Brand Alternatives
- Embeta HT 50 Tablet ER