bentor eye drop - Betamethasone (0.1% w/w) + Neomycin (0.5% w/w) medicine

bentor eye drop - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Indoco Remedies Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is bentor eye drop used for?

Betasone N Eye/Ear Drops (Betamethasone + Neomycin) is used to treat OPHTHAL OTOLOGICALS. It contains Betamethasone (0.1% w/w) + Neomycin (0.5% w/w), which Betamethasone suppresses inflammation by inhibiting phospholipase A2, reducing p. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Betamethasone + Neomycin
  • Manufacturer: Indoco Remedies Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š bentor eye drop Uses & Benefits

Treatment of steroid-responsive inflammatory conditions of the eye and ear with concurrent bacterial infection or risk of infection.

Off-label uses: None commonly reported.

๐Ÿ“‹ Drug Information

Generic Name(s)Betamethasone + Neomycin
Brand NameBetasone N Eye/Ear Drops
ManufacturerIndoco Remedies Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL OTOLOGICALS
Action ClassCorticosteroid + Aminoglycoside Antibiotic
Route of AdministrationOphthalmic and otic topical.
StorageStore at 15-30ยฐC; protect from light; keep tightly closed.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption from ophthalmic/otic use; absorption increased with inflamed mucosa or prolonged use.
DistributionDistributes locally in eye/ear; systemic distribution negligible at recommended doses.
Protein BindingBetamethasone: ~64% bound to albumin; Neomycin: negligible binding.
MetabolismBetamethasone: Hepatic via CYP3A4; Neomycin: not metabolized.
Half-LifeBetamethasone: 36-54 hours; Neomycin: 2-3 hours (systemic).
ExcretionBetamethasone: Renal (primarily as metabolites); Neomycin: Renal (unchanged).
BioavailabilityLow systemic bioavailability due to topical administration.
Onset of ActionWithin 24-48 hours for anti-inflammatory effect.
Peak Plasma TimeNot applicable for topical use; systemic levels negligible.
Duration of ActionVaries; typically 4-6 hours for local effect.

How It Works

Betamethasone suppresses inflammation by inhibiting phospholipase A2, reducing prostaglandin and leukotriene synthesis. Neomycin binds to bacterial 30S ribosomal subunit, causing misreading of mRNA and inhibiting protein synthesis.

Mechanism Steps

1Betamethasone binds to glucocorticoid receptor (GR) in cytoplasm.
2GR-ligand complex translocates to nucleus and modulates gene transcription.
3Increases lipocortin synthesis, inhibiting phospholipase A2.

๐Ÿ’ก How to Take bentor eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bentor eye drop

โœ… Common Side Effects

  • Transient stinging or burning
  • Blurred vision
  • Ear discomfort

๐Ÿšจ Serious Side Effects

  • Secondary infection
  • Increased intraocular pressure
  • Glaucoma
  • Cataract
  • Ototoxicity
  • Nephrotoxicity

โš ๏ธ Rare Side Effects

  • Allergic contact dermatitis
  • Adrenal suppression (prolonged use)
  • Perforation of tympanic membrane

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate Possible increased INR with systemic absorption (rare).
Aminoglycosides (systemic) Major Additive ototoxicity and nephrotoxicity.
Loop diuretics Moderate Increased risk of ototoxicity.

๐Ÿšจ Major Interactions

  • Aminoglycosides (systemic)
  • Ototoxic drugs
  • Nephrotoxic drugs

โšก Moderate Interactions

  • Loop diuretics
  • Neuromuscular blocking agents

โ„น๏ธ Minor Interactions

  • Other topical medications

๐Ÿฝ๏ธ Food Interactions

None known.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to betamethasone, neomycin, or any component; viral, fungal, or tubercular infections; untreated bacterial infections; perforated tympanic membrane (for otic use).

๐Ÿ“Š Monitoring Parameters

Intraocular pressure (if prolonged use), signs of secondary infection, hearing (if otic use), renal function (if prolonged use).

๐Ÿคฑ Lactation Safety

Caution; minimal systemic absorption, but avoid prolonged use.

๐Ÿ’Š Overdose Management

Unlikely due to topical use; if ingested, supportive care; monitor for electrolyte imbalance and adrenal suppression.

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

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