Benidin Trio Tablet - Uses, Price, Side Effects
What is benidin trio tablet used for?
Benidin Trio Tablet is a combination of Benidipine (a calcium channel blocker) and Telmisartan (an angiotensin receptor blocker) used to treat hypertension. It works by relaxing blood vessels, lowering blood pressure, and reducing the risk of stroke and heart attack.
- Generic Name: Benidipine + Telmisartan
- Manufacturer: Lloyd Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ benidin trio tablet Uses & Benefits
Hypertension, chronic stable angina (benidipine component).
Off-label uses: Heart failure (telmisartan), diabetic nephropathy (telmisartan).
๐ Drug Information
| Generic Name(s) | Benidipine + Telmisartan |
| Brand Name | Benitowa-TM Tablet |
| Manufacturer | Lloyd Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + Angiotensin II receptor blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Benidipine inhibits calcium influx into vascular smooth muscle, causing vasodilation; Telmisartan blocks angiotensin II AT1 receptors, reducing vasoconstriction and aldosterone secretion.
Mechanism Steps
๐ก How to Take benidin trio tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of benidin trio tablet
โ Common Side Effects
- Dizziness
- Headache
- Flushing
- Peripheral edema
- Cough
- Diarrhea
- Fatigue
๐จ Serious Side Effects
- Angioedema
- Hyperkalemia
- Renal impairment
- Hypotension
- Syncope
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Thrombocytopenia
- Leukopenia
- Stevens-Johnson syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Lithium | Moderate | Increased lithium toxicity risk |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Potassium-sparing diuretics | Major | Hyperkalemia risk |
๐จ Major Interactions
- Lithium
- Potassium-sparing diuretics
- ACE inhibitors
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampin)
โก Moderate Interactions
- NSAIDs
- Antidiabetic agents
- Digoxin
- Warfarin
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
Grapefruit juice (may increase benidipine levels), High-fat meal may reduce telmisartan absorption
๐ท Alcohol Interaction
May potentiate hypotensive effects; avoid excessive alcohol.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, pregnancy, bilateral renal artery stenosis, severe hypotension, cardiogenic shock, history of angioedema with ARBs.
๐ Monitoring Parameters
Blood pressure, heart rate, serum potassium, renal function, liver function.
๐คฑ Lactation Safety
Not recommended; avoid breastfeeding.
๐ Overdose Management
Symptomatic treatment; monitor blood pressure, heart rate; consider gastric lavage, activated charcoal; IV fluids and vasopressors if needed.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.