benidin 4 tablet - Benidipine (4mg) medicine

benidin 4 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Lloyd Healthcare Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is benidin 4 tablet used for?

Benitowa 4 Tablet (Benidipine) is used to treat CARDIAC. It contains Benidipine (4mg), which Blocks voltage-dependent L-type calcium channels, inhibiting calcium influx into. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Benidipine
  • Manufacturer: Lloyd Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š benidin 4 tablet Uses & Benefits

Hypertension, angina pectoris

Off-label uses: Raynaud's phenomenon, chronic kidney disease

๐Ÿ“‹ Drug Information

Generic Name(s)Benidipine
Brand NameBenitowa 4 Tablet
ManufacturerLloyd Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blockers- Dihydropyridines (DHP)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration
DistributionWidely distributed; high affinity for vascular smooth muscle
Protein Binding>99%
MetabolismHepatic via CYP3A4
Half-Life20-30 hours
ExcretionFecal (60%) and renal (40%)
BioavailabilityApproximately 10-20% due to first-pass metabolism
Onset of Action1-2 hours
Peak Plasma Time2-4 hours
Duration of Action24 hours

How It Works

Blocks voltage-dependent L-type calcium channels, inhibiting calcium influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure.

Mechanism Steps

1Benidipine binds to L-type calcium channels on vascular smooth muscle and cardiac muscle cells.
2Inhibition of calcium influx prevents calcium-dependent contraction.
3Vascular smooth muscle relaxation leads to vasodilation and decreased peripheral vascular resistance.

๐Ÿ’ก How to Take benidin 4 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of benidin 4 tablet

โœ… Common Side Effects

  • Headache
  • Dizziness
  • Flushing
  • Peripheral edema
  • Palpitations

๐Ÿšจ Serious Side Effects

  • Severe hypotension
  • Angina exacerbation
  • Hepatotoxicity
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Gingival hyperplasia
  • Gynecomastia
  • Leukopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased benidipine plasma concentration
Rifampin Major Decreased benidipine efficacy
Grapefruit juice Moderate Increased benidipine levels
Beta-blockers Moderate Additive bradycardia and hypotension
Digoxin Moderate Increased digoxin levels
Cimetidine Minor Slight increase in benidipine levels
Antacids Minor Reduced absorption of benidipine

๐Ÿšจ Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole)
  • CYP3A4 inducers (e.g., rifampin, phenytoin)
  • Other antihypertensives (additive effect)

โšก Moderate Interactions

  • Grapefruit juice
  • Beta-blockers
  • Digoxin

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Antacids

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice increases plasma concentration; avoid concurrent use.

๐Ÿท Alcohol Interaction

May enhance hypotensive effect; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to benidipine or dihydropyridines, severe hypotension, cardiogenic shock, unstable angina, acute myocardial infarction

๐Ÿ“Š Monitoring Parameters

Blood pressure, heart rate, liver function tests, renal function

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; monitor blood pressure and heart rate; administer vasopressors if needed

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for benidin 4 tablet

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Alternative brands with exact same active ingredient (Benidipine (4mg)):

Medical Note: Always consult your doctor before switching medications.

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