benidin m 4mg/25mg tablet sr
What is benidin m 4mg/25mg tablet sr used for?
Benidin M 4mg/25mg Tablet SR (Benidipine + Metoprolol Succinate) is used to treat CARDIAC. It contains Benidipine (4mg) + Metoprolol Succinate (25mg), which Benidipine: Blocks L-type calcium channels, causing vasodilation; Metoprolol: Se. Always consult your doctor before use. Take as prescribed.
- Generic Name: Benidipine + Metoprolol Succinate
- Manufacturer: Lloyd Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ benidin m 4mg/25mg tablet sr Uses & Benefits
Hypertension, angina pectoris.
Off-label uses: Migraine prophylaxis, essential tremor (metoprolol).
๐ Drug Information
| Generic Name(s) | Benidipine + Metoprolol Succinate |
| Brand Name | Benidin M 4mg/25mg Tablet SR |
| Manufacturer | Lloyd Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + Beta-blocker |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Benidipine: Blocks L-type calcium channels, causing vasodilation; Metoprolol: Selectively blocks beta-1 adrenergic receptors, reducing heart rate and contractility.
Mechanism Steps
๐ก How to Take benidin m 4mg/25mg tablet sr
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of benidin m 4mg/25mg tablet sr
โ Common Side Effects
- Dizziness
- Fatigue
- Bradycardia
- Headache
- Edema
- Nausea
๐จ Serious Side Effects
- Heart block
- Severe bradycardia
- Hypotension
- Bronchospasm
- Heart failure exacerbation
โ ๏ธ Rare Side Effects
- Thrombocytopenia
- Hepatitis
- Stevens-Johnson syndrome
- Lupus-like syndrome
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | Increased risk of bradycardia and heart block |
| Clonidine | Major | Rebound hypertension on withdrawal |
| Digoxin | Major | Increased digoxin levels, risk of toxicity |
| NSAIDs | Moderate | Reduced antihypertensive effect |
| Grapefruit juice | Moderate | Increased benidipine concentration |
๐จ Major Interactions
- Verapamil
- Diltiazem
- Clonidine
- Digoxin
- Antiarrhythmics
โก Moderate Interactions
- CYP2D6 inhibitors
- CYP3A4 inhibitors
- NSAIDs
- Antihypertensives
โน๏ธ Minor Interactions
- Cimetidine
- Rifampin
๐ฝ๏ธ Food Interactions
Avoid grapefruit juice (increases benidipine levels).
๐ท Alcohol Interaction
May potentiate hypotensive effect.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Sick sinus syndrome, heart block (2nd/3rd degree), cardiogenic shock, severe bradycardia, hypotension, decompensated heart failure, asthma, COPD.
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, signs of heart failure, renal function.
๐คฑ Lactation Safety
Metoprolol excreted in breast milk; benidipine unknown. Caution advised.
๐ Overdose Management
Supportive care; atropine for bradycardia, vasopressors for hypotension, glucagon for beta-blocker overdose.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.