bdsure 11.25mg injection - Leuprolide (11.25mg) medicine

bdsure 11.25mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ BDR Pharmaceuticals Internationals Pvt ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is bdsure 11.25mg injection used for?

Agopride Injection (Leuprolide) is used to treat GYNAECOLOGICAL. It contains Leuprolide (11.25mg), which GnRH agonist; continuous stimulation downregulates pituitary GnRH receptors, red. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Leuprolide
  • Manufacturer: BDR Pharmaceuticals Internationals Pvt
  • Form: Allopathy
  • Pregnancy Category: X
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š bdsure 11.25mg injection Uses & Benefits

Endometriosis, uterine fibroids, central precocious puberty, prostate cancer (male), assisted reproduction

Off-label uses: Breast cancer, transgender hormone therapy, hirsutism

๐Ÿ“‹ Drug Information

Generic Name(s)Leuprolide
Brand NameAgopride Injection
ManufacturerBDR Pharmaceuticals Internationals Pvt
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassGNRH agonists/analogue
Route of AdministrationSubcutaneous or intramuscular injection
StorageStore at 20-25ยฐC; protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after subcutaneous or intramuscular injection
DistributionDistributes widely; volume of distribution ~27 L
Protein Binding~43-49% bound to plasma proteins
MetabolismMetabolized primarily by peptidases; not significantly hepatic
Half-Life~3 hours (single dose); prolonged with depot formulations
ExcretionRenal (primarily as metabolites)
Bioavailability~90% after subcutaneous injection
Onset of ActionInitial flare (1-2 weeks) then suppression (2-4 weeks)
Peak Plasma Time1-2 hours after injection
Duration of Action1 month (depot formulation)

How It Works

GnRH agonist; continuous stimulation downregulates pituitary GnRH receptors, reducing LH and FSH secretion, thereby suppressing gonadal steroid production

Mechanism Steps

1Binds to GnRH receptors on pituitary gonadotropes
2Initial stimulation causes LH and FSH release (flare effect)
3Continuous exposure desensitizes receptors

๐Ÿ’ก How to Take bdsure 11.25mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bdsure 11.25mg injection

โœ… Common Side Effects

  • Hot flashes
  • Sweating
  • Headache
  • Nausea
  • Injection site reactions
  • Vaginal dryness
  • Decreased libido

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Seizures
  • Pituitary apoplexy
  • Spinal cord compression
  • QT prolongation

โš ๏ธ Rare Side Effects

  • Osteoporosis
  • Hyperglycemia
  • Depression
  • Thromboembolism

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Estrogen-containing medications Major May counteract therapeutic effect
Progestins Major May counteract therapeutic effect
Gonadotropins Major May interfere with ovulation induction
Antidiabetic agents Moderate May alter glucose metabolism
Corticosteroids Moderate May increase risk of bone loss
Anticoagulants Moderate May increase bleeding risk

๐Ÿšจ Major Interactions

  • Estrogen-containing medications
  • Progestins
  • Gonadotropins

โšก Moderate Interactions

  • Antidiabetic agents
  • Corticosteroids
  • Anticoagulants

โ„น๏ธ Minor Interactions

  • None significant

๐Ÿฝ๏ธ Food Interactions

None known

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Pregnancy, lactation, undiagnosed vaginal bleeding, hypersensitivity to GnRH agonists

๐Ÿ“Š Monitoring Parameters

Hormone levels (LH, FSH, estradiol/testosterone), bone density, lipid profile, blood glucose

๐Ÿคฑ Lactation Safety

Not recommended; may suppress lactation

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote

โฐ Missed Dose

Administer as soon as remembered; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bdsure 11.25mg injection

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Alternative brands with exact same active ingredient (Leuprolide (11.25mg)):

Medical Note: Always consult your doctor before switching medications.

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