baxmether 80mg/480mg tablet - Arteether (80mg) + Lumefantrine (480mg) medicine

baxmether 80mg/480mg tablet

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🏭 Baxton Pharmacia 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

What is baxmether 80mg/480mg tablet used for?

This medicine contains Arteether (80mg) + Lumefantrine (480mg) and is used to treat ANTI MALARIALS. Arteether: produces free radicals that damage parasite membranes; Lumefantrine: inhibits heme polyme. Always consult your doctor before use.

  • Generic Name: Arteether + Lumefantrine
  • Manufacturer: Baxton Pharmacia
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 baxmether 80mg/480mg tablet Uses & Benefits

Uncomplicated Plasmodium falciparum malaria

Off-label uses: Treatment of other Plasmodium species

📋 Drug Information

Generic Name(s)Arteether + Lumefantrine
Brand NameAlpha Num 80mg/480mg Tablet
ManufacturerBaxton Pharmacia
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial
Route of AdministrationOral
StorageStore at 25°C (77°F); protect from light and moisture
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionArteether is rapidly absorbed; Lumefantrine absorption is enhanced with food.
DistributionArteether widely distributed; Lumefantrine highly protein-bound.
Protein BindingArteether: ~95%; Lumefantrine: >99%
MetabolismArteether: hepatic via CYP3A4; Lumefantrine: hepatic via CYP3A4
Half-LifeArteether: ~23 hours; Lumefantrine: ~4-6 days
ExcretionArteether: feces and urine; Lumefantrine: primarily feces
BioavailabilityArteether: not well defined; Lumefantrine: increased with fat-rich food
Onset of ActionArteether: rapid; Lumefantrine: slower
Peak Plasma TimeArteether: 2-3 hours; Lumefantrine: 6-8 hours
Duration of ActionArteether: short; Lumefantrine: prolonged

How It Works

Arteether: produces free radicals that damage parasite membranes; Lumefantrine: inhibits heme polymerization

Mechanism Steps

1Arteether is activated by heme iron to produce free radicals
2Free radicals alkylate parasite proteins and membranes
3Lumefantrine inhibits heme polymerization
4Accumulation of toxic heme kills the parasite

💡 How to Take baxmether 80mg/480mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of baxmether 80mg/480mg tablet

✅ Common Side Effects

Headache
Nausea
Vomiting
Abdominal pain
Diarrhea

🚨 Serious Side Effects

QT prolongation
Severe allergic reactions
Hepatotoxicity

⚠️ Rare Side Effects

Hemolytic anemia
Neurotoxicity

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major Increased arteether/lumefantrine levels
Rifampin Major Decreased arteether/lumefantrine levels
Warfarin Major Increased bleeding risk

🚨 Major Interactions

  • CYP3A4 inhibitors
  • CYP3A4 inducers
  • Anticoagulants

⚡ Moderate Interactions

  • Anticonvulsants
  • Antiretrovirals
  • Macrolide antibiotics

🍷 Alcohol Interaction

Avoid alcohol; may increase hepatotoxicity risk

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to artemisinin derivatives or lumefantrine; severe hepatic impairment

🤱 Lactation Safety

Excreted in breast milk; caution advised

💊 Overdose Management

Symptomatic and supportive care; monitor ECG

⏰ Missed Dose

Take as soon as remembered; do not double dose

🔄 Substitutes for baxmether 80mg/480mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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