bact o tablet - Ofloxacin (200mg) + Lactobacillus (60Million spores) medicine

Bact O Tablet: Complete Medicine Guide

No reviews yet
🏭 Domagk Smith Labs Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
🤰 Pregnancy Category Ofloxacin is not recommended during pregnancy unless the potential benefit justifies the potential risk to the fetus. Fluoroquinolones have been associated with cartilage damage in immature animals. Consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe or bloody diarrhea
  • Sudden pain or swelling in a tendon, especially the Achilles tendon
  • Numbness, tingling, or weakness in hands or feet
  • Seizures, confusion, or hallucinations
  • Rash, hives, or swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Irregular heartbeat or palpitations

If experiencing severe symptoms, call emergency services immediately.

What is bact o tablet used for?

This medicine is a combination of Ofloxacin, an antibiotic, and Lactobacillus, a probiotic. It is used to treat various bacterial infections and helps prevent antibiotic-associated diarrhea.

  • Generic Name: Ofloxacin + Lactobacillus
  • Manufacturer: Domagk Smith Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bact o tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ओफ्लोक्सासिन और लैक्टोबैसिलस का संयोजन है। ओफ्लोक्सासिन एक एंटीबायोटिक है जो बैक्टीरिया के संक्रमण का इलाज करता है, जैसे मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और प्रोस्टेटाइटिस। लैक्टोबैसिलस एक प्रोबायोटिक है जो आंतों में अच्छे बैक्टीरिया को बनाए रखने में मदद करता है और एंटीबायोटिक से होने वाले दस्त को रोकता है। यह दवा वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और नींद न आना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें टेंडन टूटना, तंत्रिका क्षति, दौरे, गंभीर एलर्जी और क्लोस्ट्रीडियम डिफिसाइल दस्त शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को एक गिलास पानी के साथ लें। एंटासिड, आयरन, जिंक या मैग्नीशियम सप्लीमेंट के साथ इस दवा को लेने से 2 घंटे पहले या बाद में लें। पर्याप्त पानी पिएं। धूप से बचें और सनस्क्रीन का उपयोग करें। चक्कर आने पर वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। शराब का सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 bact o tablet Uses & Benefits

[{"condition":"Urinary tract infections","description":"Used to treat uncomplicated and complicated urinary tract infections caused by susceptible bacteria such as Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against certain bacterial respiratory infections, including acute exacerbations of chronic bronchitis and community-acquired pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for bacterial skin infections such as cellulitis, abscesses, and wound infections caused by susceptible gram-positive and gram-negative bacteria.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"Used in the treatment of gonorrhea and chlamydia infections, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Prostatitis","description":"Ofloxacin penetrates prostate tissue well and is used to treat chronic bacterial prostatitis caused by susceptible bacteria.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for severe traveler's diarrhea caused by susceptible bacteria, though other antibiotics are often preferred.","evidence":"Limited"},{"condition":"Diverticulitis","description":"May be used off-label in combination with other antibiotics for mild diverticulitis, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Prostatitis, Gonorrhea

📋 Drug Information

Generic Name(s)Ofloxacin + Lactobacillus
Brand NameA Flox 100mg Tablet
ManufacturerDomagk Smith Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassFluoroquinolone antibiotic + Probiotic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food if it upsets your stomach.
2
Complete the full course even if you feel better after a few days.
3
Avoid taking antacids, iron, zinc, or magnesium supplements within 2 hours of this medicine.
4
Drink plenty of water throughout the day to stay hydrated.
5
Avoid alcohol while taking this medicine as it can increase dizziness and drowsiness.
6
Use sunscreen and avoid excessive sun exposure due to risk of photosensitivity.
7
Report any tendon pain, numbness, or tingling immediately.
8
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning during urination
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Cough with fever
May be used for bacterial respiratory infections.
Likely Use
❌
Runny nose and sneezing
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOfloxacin is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The bioavailability is approximately 98%. Food may slightly delay the time to peak concentration but does not significantly reduce the extent of absorption.
DistributionOfloxacin is widely distributed throughout the body. It penetrates well into many tissues and body fluids, including urine, bile, sputum, prostate, and skin. The apparent volume of distribution is approximately 1.5-2.5 L/kg. Protein binding is about 20-30%.
Protein BindingApproximately 20-30% bound to plasma proteins.
MetabolismOfloxacin undergoes limited metabolism in the liver. Only a small fraction is metabolized to inactive metabolites.
Half-LifeThe elimination half-life of ofloxacin is approximately 4-5 hours in patients with normal renal function. It is prolonged in patients with renal impairment.
ExcretionOfloxacin is primarily excreted unchanged in the urine by glomerular filtration and tubular secretion. About 70-80% of an oral dose is recovered in urine as unchanged drug. A small amount is excreted in feces.
BioavailabilityApproximately 98%
Onset of ActionOfloxacin begins to work within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma Time1-2 hours after oral administration.
Duration of ActionThe antibacterial effect lasts for approximately 12-24 hours, allowing for once or twice daily dosing.

How It Works

Ofloxacin is a synthetic fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By blocking these enzymes, ofloxacin prevents bacterial cell division and leads to bacterial death. Lactobacillus is a probiotic that helps maintain the natural gut flora, which can be disrupted by antibiotic therapy, thereby reducing the risk of antibiotic-associated diarrhea.

Mechanism Steps

1
Entry into bacterial cell: Ofloxacin penetrates the bacterial cell wall and enters the cytoplasm.
2
Inhibition of DNA gyrase: Ofloxacin binds to the DNA gyrase enzyme, preventing it from supercoiling bacterial DNA, which is necessary for replication.
3
Inhibition of topoisomerase IV: Ofloxacin also inhibits topoisomerase IV, which is involved in separating replicated DNA strands, leading to further disruption of DNA processes.
4
Bacterial cell death: The inhibition of these enzymes leads to double-strand DNA breaks and ultimately bacterial cell death.
5
Probiotic effect: Lactobacillus spores germinate in the gut and help restore beneficial bacteria that may be killed by the antibiotic.

💡 How to Take bact o tablet

Strength: Tablet containing Ofloxacin 200 mg and Lactobacillus 60 million spores.

1Take the tablet with a full glass of water.
2Swallow the tablet whole. Do not crush or chew.
3Take with or without food, but if it upsets your stomach, take with a meal.
4If you are taking antacids, sucralfate, or mineral supplements, take this medicine at least 2 hours before or 2 hours after them.
5Take at evenly spaced intervals as prescribed by your doctor.
6Complete the full course of therapy even if you feel better after a few days.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally every 12 hours or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney function, and other factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Complete the full course as prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Ofloxacin is generally not recommended for children under 18 years except in specific circumstances under specialist supervision.
Elderly DosageElderly patients may have reduced renal function and are at higher risk of tendon rupture, CNS effects, and QT prolongation. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For patients with creatinine clearance less than 50 mL/min, the dose may need to be reduced or the dosing interval increased. Consult your doctor for specific recommendations.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400 mg of ofloxacin, but this must be individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Separate by 2 hours
Calcium can reduce absorption of ofloxacin.
Fortified cereals
Separate by 2 hours
Iron and zinc can reduce absorption.
Caffeine
Limit intake
May increase caffeine effects.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of bact o tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. The Lactobacillus component may help. If diarrhea is severe or bloody, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Insomnia (Common (5-10%))
Take the medicine earlier in the day if possible. Practice good sleep hygiene.

🚨 Serious Side Effects

Tendinitis or tendon rupture (Rare (<0.1%))
Seek immediate medical attention if you experience pain, swelling, or inflammation in a tendon, especially the Achilles tendon.
Peripheral neuropathy (Rare (<0.1%))
Report symptoms such as numbness, tingling, burning, or weakness in the hands or feet to your doctor immediately.
Central nervous system effects (Rare (<0.1%))
Seek medical help if you experience seizures, confusion, hallucinations, or severe dizziness.
Severe allergic reactions (Rare (<0.1%))
Get emergency help if you have rash, hives, swelling of the face, lips, tongue, or throat, or difficulty breathing.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop severe, persistent diarrhea, abdominal pain, or fever.

⚠️ Rare Side Effects

Photosensitivity
Avoid excessive sun exposure and use sunscreen. Report any skin rash or sunburn-like reaction.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or right upper abdominal pain to your doctor.
Nephrotoxicity
Report decreased urine output or swelling. Your doctor may monitor kidney function.
Blood dyscrasias
Report unusual bleeding, bruising, or signs of infection. Blood tests may be needed.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Major
Warfarin Major
Theophylline Major
NSAIDs Major
Corticosteroids Major
Oral hypoglycemics Moderate
Probenecid Moderate
Cimetidine Moderate
Furosemide Moderate
Didanosine Minor

🚨 Major Interactions

  • Antacids, sucralfate, and mineral supplements (iron, zinc, magnesium, calcium)
  • Warfarin
  • Theophylline
  • NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids

⚡ Moderate Interactions

  • Oral hypoglycemics (e.g., glibenclamide)
  • Probenecid
  • Cimetidine
  • Furosemide

🍷 Alcohol Interaction

Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ofloxacin, other fluoroquinolones, or any component of the formulation","History of tendon disorders associated with fluoroquinolone use","Myasthenia gravis (may exacerbate muscle weakness)","Children under 18 years (except for specific indications under specialist supervision)","Pregnancy and breastfeeding (unless clearly needed)","Patients with known QT prolongation or uncorrected hypokalemia"]

⚠️ Warnings & Precautions

["Fluoroquinolones, including ofloxacin, have been associated with disabling and potentially irreversible serious adverse reactions, including tendinitis, tendon rupture, peripheral neuropathy, and CNS effects. Reserve use for patients with no alternative treatment options.","May cause dizziness and lightheadedness. Avoid driving or operating machinery until you know how this medicine affects you.","May cause photosensitivity. Avoid excessive sun exposure and use sunscreen.","May worsen muscle weakness in patients with myasthenia gravis. Avoid use in these patients.","May cause hypoglycemia, especially in diabetic patients. Monitor blood glucose closely.","May prolong QT interval. Use with caution in patients with risk factors.","Clostridium difficile-associated diarrhea may occur. If diarrhea develops, consider this diagnosis.","Do not use in patients with a history of tendon disorders related to fluoroquinolone use."]

🤱 Lactation Safety

Ofloxacin is excreted in breast milk. Because of the potential risk of serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, dizziness, and confusion. Treatment is symptomatic and supportive. Adequate hydration should be maintained. Ofloxacin is not effectively removed by hemodialysis or peritoneal dialysis.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop the course early, even if you feel better, as this can lead to antibiotic resistance. Take the tablet with a full glass of water, with or without food. Avoid taking antacids, sucralfate, or mineral supplements containing iron, zinc, or magnesium within 2 hours before or after this medicine, as they can reduce its absorption. Drink plenty of fluids to stay hydrated. Avoid excessive sunlight and use sunscreen, as ofloxacin can make your skin more sensitive to sunlight. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. Inform your doctor if you have kidney or liver problems, diabetes, myasthenia gravis, or a history of tendon problems. Avoid alcohol while taking this medicine. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, CNS effects, and QT prolongation. Dose adjustment may be needed based on renal function. Monitor closely for side effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Ofloxacin is not recommended during pregnancy unless clearly needed.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before certain procedures.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are usually needed, but it is important for your dentist to know your medication history.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water to help flush out the infection.
🥗
Maintain good hygiene, especially handwashing, to prevent reinfection.
😴
Get adequate rest to support your immune system.
💧
Eat a balanced diet rich in fruits and vegetables.
🧘
Avoid caffeine and alcohol as they can worsen side effects.
🌞
Use sunscreen and protective clothing when outdoors.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that put stress on tendons, especially the Achilles tendon, while taking this medicine. If you experience tendon pain, stop exercising and consult your doctor.

🥗 Diet Recommendations

Stay well hydrated by drinking water throughout the day.
Include probiotic-rich foods like yogurt to support gut health.
Avoid spicy and oily foods if you have stomach upset.
Limit caffeine intake to reduce jitteriness and insomnia.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, drowsiness, or confusion. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take it when you can rest if you experience these side effects.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately; they may advise you to stop.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to antibiotic resistance and may increase the risk of serious side effects such as tendon rupture, peripheral neuropathy, and Clostridium difficile infection. It should only be used for the prescribed duration. Regular monitoring of kidney and liver function may be needed if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Supplementing with probiotics can help maintain gut health during antibiotic therapy.

Evidence: Well-established
Increased fluid intake

Drinking plenty of water can help flush out bacteria in urinary tract infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics do not interact with vaccines. However, if you are acutely ill with a fever, your doctor may advise postponing vaccination until you recover.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or temperature extremes. Store at room temperature and protect from light and moisture. If crossing time zones, adjust dosing times gradually to maintain even intervals. Check local customs regulations for bringing prescription medications into the country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it twice daily with food and completed the 7-day course. Her symptoms improved within 3 days, and she did not experience any stomach upset, which she attributed to the Lactobacillus component. She emphasized the importance of finishing the entire course.
💡 Lesson: Taking the full course and taking with food can improve tolerability and outcomes.
👤 A 60-year-old man with chronic bronchitis
He was given this medicine for an acute exacerbation of chronic bronchitis. He was advised to avoid antacids within 2 hours of the dose. He completed the 10-day course and his cough and breathlessness improved significantly. He was monitored for tendon problems due to his age.
💡 Lesson: Elderly patients should be monitored for tendon and CNS side effects, and adherence to timing with other medications is crucial.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.

Q: What should I avoid while taking this medicine?

A: Avoid antacids, iron, zinc, magnesium supplements, and alcohol. Also avoid excessive sun exposure.

Q: Is this medicine safe for children?

A: Ofloxacin is generally not recommended for children under 18 years except in specific circumstances under specialist supervision.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for bact o tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription antibiotic and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Ofloxacin + Lactobacillus

Brand Alternatives

  • Bact O Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ofloxacin 200 mg + Lactobacillus 60 million spores","class":"Fluoroquinolone antibiotic + probiotic","primary_use":"Bacterial infections"},{"medicine":"Ciprofloxacin + Lactobacillus","composition":"Ciprofloxacin 500 mg + Lactobacillus","class":"Fluoroquinolone antibiotic + probiotic","primary_use":"Bacterial infections"},{"medicine":"Levofloxacin + Lactobacillus","composition":"Levofloxacin 500 mg + Lactobacillus","class":"Fluoroquinolone antibiotic + probiotic","primary_use":"Bacterial infections"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory